Objective:To explore the effect of cascade training appraisal effect in improving the young nurses ethics humanities cultivated manners.Methods:Since 2013 within three years of the new nursing staff in hospital, through simple after complex first, after the first standardized routine training characteristic simulation and case op-eration step training appraisal method, comparing before paramedics humanistic literacy assessment, evaluation of excellence and patient satisfaction.Results:New training evaluation method for young nurses in the clinical opera-tion assessment obviously improving the patient-centered nursing service consciousness, appraisal excellence rate of 31.25%, higher than a year before the inspection the excellence rate of 19.82%, with significant difference (P<0.05);In patients to nursing staff satisfaction survey comparison, has significant advantage (P<0.05).Con-clusions:New training appraisal method significantly improves the young nurses′own quality and medical ethics ac-complishment, can better pay attention to the humanistic care in the clinical practice, communicate with the nurse, improve the judgment in the work of the nurses in the clinical ability, emergency ability, communication ability, flexible ability and emergency ability of emergency response.For young nurses in practice to deal with the doctor-patient relationship, medical international relations, improving clinical practice ability and the patient′s comprehen-sive satisfaction has important value.

Hepatitis B ; Humans ; Th17 Cells

The growing teratoma syndrome (GTS) is defined as the development of mature low-grade elements in the absence of a recurrent non-germinomatous germ-cell tumor (NGGCT) after partial response to multimodal treatment. It is uncommon and may occur in intracranial NGGCTs. Here, we report that a 7-year-old boy with intracranial NGGCT presented with precocious puberty and developed growing teratoma syndrome only 2 weeks after the first cycle of chemotherapy.
Child ; Combined Modality Therapy ; Humans ; Pineal Gland ; Puberty, Precocious ; Teratoma

OBJECTIVE: To present the surgical outcomes of advanced epithelial ovarian cancer (AEOC) since the implementation of a personalized approach and to validate multiple predictive models for R0 resection. METHODS: Personalized strategies included: 1) Non-invasive model: preoperative clinico-radiological assessment according to Suidan criteria with a predictive score for all individuals. Patients with a score 0–2 were recommended for primary debulking surgery (PDS, group A), or otherwise were counseled on the choices of PDS, neoadjuvant chemotherapy (NAC, group B) or staging laparoscopy (S-LPS). 2) Minimally invasive model: S-LPS with a predictive index value (PIV) according to Fagotti. Individuals with a PIV < 8 underwent PDS (group C) or otherwise received NAC (group D). Intraoperative assessment (with Eisenkop, peritoneal cancer index [PCI], and Aletti scores) and surgical results were prospectively collected. RESULTS: Between September 2015 and August 2017, 161 pathologically confirmed epithelial ovarian cancer patients were included. A total of 52 (32.3%) patients had a predictive score of 0–2, and 109 (67.7%) patients had a score ≥ 3. Among these individuals, 41 (25.5%) patients received S-LPS. Finally, 110 (68.3%) patients underwent PDS (A+C), and 51 (31.7%) patients received NAC (B+D). The R0 resection rates in PDS and NAC patients were 56.4% and 60.8%, respectively. The area under the curve (AUC) of Suidan criteria was 0.548 for group (A+C). The AUC of Fagotti score was 0.702 for group C. The AUC of Eisenkop, PCI, and Aletti scores were 0.808, 0.797, and 0.524, respectively. CONCLUSION: The Suidan criteria were not effective in these AEOC patients. S-LPS was helpful in decision-making for PDS and should be endorsed in the future.
Area Under Curve ; Cohort Studies* ; Drug Therapy ; Humans ; Laparoscopy ; Ovarian Neoplasms* ; Prospective Studies* ; Research Design ; Triage*