Objective: To observe the influence of treatment with combiration of sodium ferulate and(astragalus) injection(黄芪注射液) on changes of hemorrheology and renal function in patients with early(diabetic) nephropathy(DN).Methods: One hundred and forty patients with early DN were(randomly) divided into two groups.The control group(n=70) was treated with conventional therapy for (diabetes) and diet(control) method,while the treatment group(n=70) was treated with sodium ferulate(combined) with(astragalus) injection additionally.The therapeutic course was 3 weeks.Results: In the(treatment) group,the hemorrheological parameters were(significantly) decreased(P