Objective To evaluate laparoscopic radical of serum TNF-α, TGF-β1 and IL-17 affects the surgery. Methods A total of 75 cases elderly colon cancer patients were divided into two groups according to surgical, control group (n=37) and the observation group (n=38), respectively, to expand the use of open and laparoscopic radical resec-tion extended radical mastectomy treatment. The intraoperative and postoperative conditions, serum TNF-α, TGF-β1 and IL-17 levels before and after surgery, quality of life scores before and after treatment were compared. Results (1)Surgical patients in the observation group time, blood loss, postoperative exhaust time and hospital stay were signifi-cantly lower than the control group (P<0.05); (2) 1 d postoperative serum TNF-α, TGF-β1 and IL-17 levels were sig-nificantly higher than before surgery (P<0.05), and the index levels of 5 d in observation group were significantly lower than control group after 5 d level, the differences were statistically significant (P<0.05). Conclusion Laparoscopic extended radical mastectomy and extended radical mastectomy can open an increase in serum TNF-α, TGF-β1 and IL-17 levels, but over time, the expansion of radical laparoscopic surgery in patients with serum gradually returned to the index preoperative level, but open extended radical mastectomy in patients with serum above indicators slow recovery;laparoscopic extended radical mastectomy can improve prognosis for patients.

Objective: To explore the practicability and reproducibility of judgment method and assessment indexes for the end point of double eyelid surgery using 4+ 1 photography in supine position. Methods: From 2017 October to 2018 October, 158 patients were included and randomly divided into 2 groups. Photos were taken by 4 + 1 photography in supine position of 79 patients, while other 79 patients in control group were evaluated by traditional observation. By 4+ 1 photography in supine position, the surgeon stood at the head side of the patient, taking photos with eyes movement: looking straight forward, looking up, looking downward and eye-closed. It was to observe the upper eyelid creases, upper and lower tissues of double eyelid creases, and upper and lower eyelid margo palpebrae. In addition, the surgeon looked from patient′s feet to observe the indexes such as upper margo palpebrae, to make a decision whether the surgery could finish. In control group, the surgeon observed the upper eyelid creases, upper and lower tissues of double eyelid creases and upper and lower eyelid margo palpebrae. The patient has to sit if necessary. Results: All 158 patients were performed double eyelid surgery successfully. Average times of valuating end point was 1.20 by 4+ 1 Photography in supine position, and 1.53 in control group. The operation time of 4+ 1 photography group is (151.65±21.58) s, and control group were (241.53±33.53) s. The satisfaction level was increased to 89.87% in 4+ 1 photography group, compared to 78.48% in control group. Conclusions The 4+ 1 Photography method is simple and easy to practice. The observation indexes are accurate and comprehensive. It is useful in determining the end point of double eyelid plasty in supine position.