1.Investigation on Quantitative Diagnosis of Clinical Manifestations of TCM Heart Disease Diagnosed on the Basis of Differentiation of Blood and Qi
Zhaokai YUAN ; Xiaoqing ZHOU ; Fuyuan FAN
Journal of Traditional Chinese Medicine 1993;0(05):-
In the light of mathematical maximum likily hood method, the conditioned probability of clinical manifestations in TCM syndrome of asthenic heart qi - and blood and control group were calculated to establish a " List of Quantitative Diagnostic Index of TCM Manifestations Differentiation for Qi and Blood in Heart Disease". Based on the scoring of the above list, the rate of coincidence of retro - spective test of the three signs were 92. 70%, 93. 20%, 94. 98% respectively, and that of prospective test were 84. 61%, 81.82%, 87. 50% respectively. Authors' address: Institute of diagnostics, Hunan College of TCM, Changsha, Hunan 410027
2.Meta-analysis on Relationship between Serum Total Cholesterol and Coronary Heart Disease of Phlegm and Blood Stasis Syndrome
Songren YU ; Li ZHOU ; Shaomin CHENG ; Zhaokai YUAN
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(6):1383-1387
This study was aimed to find out the relationship between the serum total cholesterol ( TC ) and coronary heart disease ( CHD ) of phlegm and blood stasis syndrome . Meta -analysis was used on the comprehensive analysis of ten research literatures on TC content of CHD patients with phlegm-turbid syndrome, blood-stasis syndrome and normal control . The results showed that the content of TC was 0.99-2.426 times h igher standard deviation in the blood-stasis syndrome patients than in the normal control, Totalcombined = 0.71. And the 95% confidence intervals of Totalcombined was 0.16-1.25. And the content of TC was 1.019-3.761 times higher standard deviation in the phlegm-turbid syndrome than in the normal control, Totalcombined= 1 . 05 . And the 95% confidence intervals of Totalcombined was 0 . 43-1 . 68 . It was concluded that there were significant variations of TC content in CHD patients with blood-stasis and phlegm-turbid syndrome compared to normal control . Therefore , abnormal changes of TC content can be used as one of the objective CHD diagnostic criteria of phlegm and blood stasis syndrome .
3.Advances in the relationship between obstructive sleep apnea and enuresis in children
International Journal of Pediatrics 2023;50(2):81-85
Enuresis(NE)and obstructive sleep apnea(OSA)are common diseases in children, which often cause various social and psychological problems and the coexistence of both seriously affects the physical and mental health of children.At present, there have been many speculations about whether OSA can cause NE and the specific pathogenesis.OSA may be susceptible to NE due to abnormal secretion of humoral factors, sleep-wake disorders, bladder dysfunction, obesity, and psychosomatic factors, among which abnormal secretion of humoral factors and sleep-wake disorders may play a crucial role.In addition, it has been suggested that adenotonsillectomy may be the best treatment option for children suffering from OSA with NE when upper airway obstruction is present.This article summarizes the relationship between NE and OSA and how to treat them, aiming to provide a reference for the clinical treatment of OSA and NE.
4.Differentiation and Treatment of Bipolar Disorder based on Qi, Phlegm, Fire and Deficiency
Yunfeng YU ; Gang HU ; Manli ZHOU ; Xiaoxin LUO ; Xiahui ZHOU ; Weixiong JIAN ; Zhaokai YUAN
Journal of Traditional Chinese Medicine 2023;64(19):2037-2040
Bipolar disorder (BD) is considered to be mainly related to qi, phlegm, fire and deficiency. Binding constraint of liver qi is the initial cause, while phlegm and qi interact obstruction as well as phlegm and fire interact binding is the key pathogenesis of the transformation between depression and mania, and deficiency of both qi and yin is the main reason of the protracted course of disease. In clinical practice, BD is divided into binding constraint of liver qi pattern, phlegm and qi interact obstruction pattern, phlegm and fire interact binding pattern, and deficiency of both qi and yin pattern, which can be treated with Jinyu Shugan Powder (金玉疏肝散), Kaiyu Wendan Decoction (开郁温胆汤), Qingxin Huatan Decoction (清心化痰汤), and Baihe Shengmai Beverage (百合生脉饮) in their modifications respectively; moreover, Guanye Jinsitao (Herba Hyperici Perforati) is usually used to rectify qi, relieve phlegm and clear heat. It is also suggested to put focus on the prevention and treatment of qi, phlegm and heat simultaneously, and modify the medicinals flexibly in accordance with the pathogenesis evolution and the abnormal exuberance.
5.Voiding diary predicts the therapeutic effects on primary monosymptomatic nocturnal enuresis
Shuai LI ; Shuai YANG ; Zhaokai ZHOU ; Yanping ZHANG ; Jing YANG ; Guoxian ZHANG ; Qingwei WANG ; Wei LU ; Jianguo WEN
Journal of Modern Urology 2023;28(4):283-286
【Objective】 To investigate the possibility of using voiding diary (VD) to predict desmopressin diacetate arginine vasopressin (DDAVP) and enuresis alarm (EA) in the treatment of primary monosymptomatic nocturnal enuresis (PMNE). 【Methods】 A total of 100 children (aged 6 to 14 years) with PMNE treated during Jan.2018 and Oct.2022 were involved. Bladder type was classified with two-week VD. Pseudo-randomization was performed using the Danish REDCap system to group patients into the randomized group and VD group. All patients were treated for 8 weeks. 【Results】 A total of 82 cases met the inclusive criteria. The effective rate was 82.50% (33/40) and 59.52% (25/42) in the VD and randomized groups, respectively, with significant difference (χ2=5.224, P=0.022). In the randomized group, if VD was not considered, the effective rate in the DDAVP and EA subgroups was 81.82% (18/22) and 25.00% (5/20), respectively, with significant difference (χ2=13.625, P=0.000). 【Conclusion】 VD can predict the therapeutic effects of PMNE. It is necessary to record VD for two weeks before selecting appropriate treatment methods. For patients who choose treatment without reference to VD, DDAVP shows better response than EA, but the recurrence rate after discontinuation of treatment requires further follow-up.