1.Training doctors specifically for the suburban and rural areas
Chinese Journal of Hospital Administration 1996;0(10):-
The cultivation of medical and health personnel in the rural areas is currently confronted with severe challenges: very few graduating students go and work in the poverty-stricken or mountainous areas and there is a shortage of rural medical and health personnel. An effective mechanism for solving the problem in a short time has been the establishment of medical and health personnel training centers that recruit students specifically from the mountainous and poverty-stricken areas and assign them back there upon graduation. It has promoted the development of unique curriculums designed specifically for the training of personnel specializing in clinical medicine from rural grassroots. The establishment of long-term mechanisms that ensure the support of the development of the rural medical and health cause by urban medical and health human resources strongly guarantees the development of rural in-service education and non-academic training.
2.In vitro labeled neural stem cells of fetal rats:MRI observation
Zhaofeng ZHENG ; Rongfang WANG ; Qi WANG
Chinese Journal of Tissue Engineering Research 2015;(32):5225-5230
BACKGROUND:It is necessary to dynamicaly monitor the survival, recognition and migration of neural stem cels after implantation.
OBJECTIVE:Toin vitro label fetal rat neural stem cels using MRI technology so as to provide applied evidence of neural stem cels in nervous system repair.
METHODS:Fetal rat neural stem cels were isolated, cultured and labeled folowed by identification and cel viability detection. A rat model of cerebral ischemia-reperfusion injury was established. Fetal neural stem cels labeled by superparamagnetic iron oxide particlesin vitro were transplanted into the left brain of model rats, and unlabeled fetal rat neural stem cels transplanted into the right brain. Prussian blue staining was used to observe the colonization and migration of implanted neural stem cels. MRI tracing was employed to monitor the signal changes of neural stem cels dynamicaly afterin vivo transplantation.
RESULTS AND CONCLUSION:Over 95% fetal rat neural stem cels were labeled successfuly by superparamagnetic iron oxide particles, and under electron microscope, there were iron particles in labeled neural stem cels, which were concentrated in the lysosome and endosome. MRI results showed that the labeled neural stem cels had a changing trend of low signals. No difference was found in the cel viability between labeled and unlabeled cels, but T2WI and T2*WI signals were reduced in labeled neural stem cels. These findings confirm that superparamagnetic iron oxide-labeled fetal rat neural stem cels can highly express, and MRI tracing can be used forin vivo monitoring of neural stem cels.
3.Treatment of enchondroma of the hand with porous calcium phosphate bone bioceramic
Zhaofeng ZHANG ; Hua SHEN ; Yongchun WANG
Orthopedic Journal of China 2006;0(07):-
[Objective]To report the results of treatment of enchondroma of the hand with curettage and porous bioceramic bone grafting. [Methods]Fifteen patients with digital enchondroma were reviewed.The average follow-up period was 30 months.The final function and radiographic appearance of the surgically treated digits were analyzed.[Results]At final evaluation the bony incorporation was uneventful in all patients.The mean functional Muskuloskeletal Tumor Society Score was 29.Radiographs showed apparent partial absorption of bioceramic bone in only two patients.All digits achieved full range of motion after surgery.No complication was found.[Conclusion]Porous bioceramic bone is safe and effective as a bone-filling substance after curettage of enchondroma of the hand.
4.Nature index-based analysis of scientific research outputs in life science of some domestic colleges and universities
Lu MA ; Ting WANG ; Zhaofeng LU
Chinese Journal of Medical Library and Information Science 2015;(7):1-4
After the indexes of article count, fraction count, weighted fraction count, and domestic and interna-tional collaboration ratio were calculated using the 2014 nature index of life science issued by British Nature Pub-lishing Group as the data source, the 2014 scientific research outputs in life science of some domestic colleges and universities were analyzed with certain suggestions put forward for reducing the gap in scientific research strength between China and USA.
5.Analysis on the service capacity of village clinics in the suburb of Beij ing based on the theory of multiple stream
Xiting ZHANG ; Xiaoyan WANG ; Zhaofeng LYU
Chinese Journal of Hospital Administration 2016;32(11):863-866
The theory of multiple streams,a vehicle of public policy analysis in the West,was used to analyze the policy development at Beijing′s suburban village clinics.This approach can clarify the issue steams,policy streams,and political streams,as well as the links between them,as a reference for standardized and quickened development such clinics.
6.Spinal canal volume change and clinical significance of cervical minimally invasive lamionplasty with specimen simulation
Chunlin ZHANG ; Zhaofeng ZENG ; Hengtao TANG ; Xu YAN ; Chuangjian WANG
Chinese Journal of Tissue Engineering Research 2013;(26):4849-4856
10.3969/j.issn.2095-4344.2013.26.014
7.Application of voice acoustic analysis in microlaryngoscopic surgery
Zhaofeng ZHU ; Yuejian WANG ; Weixiong CHEN ; Ruikai CHEN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2001;(3):118-119
Objective:To evaluate the relationship between the effect of microlaryngoscopic surgery of vocal polyp and the change of all-parameters.Method:Acoustic parameters of 80 patients with vocal polyp were measured by Dr .Speech Sciente for Windows, and analyzed preoperatively and postoperatively.Result:The jitter, shimmer and NNE were different significantly between preoperative and postoperative,the NNE and shimmer were more sensitive than jitter.Conclusion:The NNE and shimmer of acoustic parameter are objective parameter to evaluate the effect of the microlaryngoscopic surgery of vocal polyp.
8.Service provision by township hospitals in Beijing
Yingchun PENG ; Zhaofeng LV ; Xiaoyan WANG ; Wei PENG ; Xiaoxia SONG
Chinese Journal of Hospital Administration 2010;26(9):681-684
Objective To probe into the current services and outcomes of township hospitals following their transformation, and their future positioning of functionality. Methods Pinpointing townships A, B and C as samples from a district in Beijing, in which field surveys were made in the township hospitals to learn their services, service provision methods and outcomes. Results Among the current services provided by these three hospitals, those of public health and primary healthcare nature in hospital A account for 50% each; those in hospital B account for 70% and 30% respectively; those in hospital C account for 60% and 40% respectively. Recommendable services provided in these hospitals include universal coverage of medical files, management of infectious diseases, public health emergency management, and immunization. Conclusion Township hospitals as the center of the 3-tier rural health service network, deserve a repositioning of their functionality to fit the health needs of residents at large.
9.The activity of DNA photolyase in vitro
Lei XU ; Wanmeng MU ; Zhaofeng LUO ; Yuzhen WANG
Chinese Pharmacological Bulletin 2003;0(10):-
Aim To study the mechanism of Escherichia coli DNA photolyase(EC 4.1.99.3) in repairing the ultraviolet induced pyrimidine dimmer lesions in DNA.Methods UV-Vis Specturum was used to measure the relationships between the enzyme activity and different state flavin ademine denucleotide(FAD).Results It was shown that the enzyme activity was the highest when FAD chromophore was in reduced state and lowest when it was in oxidated state,while the activity ranked between when the enzyme was in radical state.Partial denature was observed when the enzyme was in oxidated state and under over 30℃,yet the enzyme activity remained unchanged.The presence of MTHF chromophore enhanced the enzyme activity.Conclusion These findings provide clues for clinical application of DNA photolyase in the future.
10.Government Shoulder Heavy Responsibilities in the Establishment of Harmony Doctor-Patient Relationship
Zhaofeng LV ; Xiaoyan WANG ; Yang LU ; Lina WU
Chinese Medical Ethics 1994;0(06):-
It is shown by the typical investigation on the status of doctor-patient relationship in ten cities of China that the government should shoulder heavy responsibilities in the establishment of harmony doctor-patient relationship.On the basis of this investigation,this article reviews the governmental measure in health management and policy,analyzes the factors of governmental responsibility and presents some proposal of it.