1.Non-aneurysmal perimesencephalic subarachnoid hemorrhage
International Journal of Cerebrovascular Diseases 2015;23(4):301-305
As a special type of subarachnoid hemorrhage,the prognosis of non-aneurysmal perimesencephalic subarachnoid hemorrhage (NAPSAH) is good.In recent years,with the development and popularization of neuroimaging technology,people have gradually deepened the awareness of the disease.This article reviews the progress in the diagnosis and treatment of NAPSAH.
2.Research on visualization of ultrasonic rhinitis therapeutic apparatus based on V4L2.
Qiang ZHAO ; Deping ZENG ; Yi ZHANG
Journal of Biomedical Engineering 2014;31(5):1127-1131
This paper reports the study and design of a visualization system of the ultrasonic rhinitis therapeutic apparatus with the function of endoscopic sinus. On Linux operating platform, we captured the video data of a video capture card that connected the endoscopic sinus using Video4Linux (V4L2) that was provided by the operating system. The video images were displayed by Qt. The visualization system solved the problem that the current ultrasonic rhinitis therapeutic apparatus had to rely on the large and expensive endoscopy equipment. And this simplified the doctors' operation, met the need of monitoring nasal cavity in the process of operating, greatly reduced the costs of treatment and would contribute to the promotion of the instrument. As a result, it has been tested that the nasal endoscopic image achieved by the system is clear and smooth, and fully meet the clinical needs of ultrasonic treatment of rhinitis.
Endoscopy
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Equipment Design
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Humans
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Nasal Cavity
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surgery
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Rhinitis
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therapy
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Software
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Ultrasonics
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instrumentation
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Video Recording
3.Expressions and roles of long non-coding RNA UCA1 in tumors
Yi ZHAO ; Xingxing ZHANG ; Min XU
Journal of International Oncology 2015;(7):519-521
Urothelial carcinoma associated antigen 1(UCA1)is a highly bladder cancer-specific long non-coding RNA(lncRNA),and it does not have the function of encoding protein. UCA1 differentially expre-sses in various fetal tissues,but its expression is turned off in most adult tissues. It reactivates during tumori-genesis. Researches indicate that UCA1 may regulate cell proliferation,apoptosis,metastasis and chemoresis-tance of tumors,such as bladder cancer,breast cancer and hepatocellular cancer.
4.Research progress of long non-coding RNA in tumor epithelial-mesenchymal transition
Yi ZHAO ; Xingxing ZHANG ; Min XU
Journal of International Oncology 2015;(8):599-601
Long non-coding RNA (lncRNA)is a kind of RNA molecule which is longer than 200 nucleotides and has no capacity of coding proteins.Accumulating evidences have indicated that several lncRNAs,such as HOTAIR,MALAT-1 ,H1 9 and BANCR may promote tumor metastasis by inducing epitheli-al-mesenchymal transition.
5.Design studies and discussions of online blood volume monitoring system in hemodialysis patient data information management
Liping ZHAO ; Feihong ZHANG ; Yi ZHOU
China Medical Equipment 2014;(3):25-28
Objective: According to the relevant principles of blood volume monitoring and monitoring methods, to apply online monitoring data information management in the blood volume monitoring for hemodialysis patients. Methods:through the relevant technical form and its function of monitoring data to study and analyze of treatment parameters of hemodialysis patients described in online blood volume monitor, to achieve data analyzed by using information management system. Results: the blood volume can be visually monitored during the hemodialysis to understand changes in the blood volume of hemodialysis patients, it helps to avoid the occurrence of hypotension and evaluation of patients with dry weights during the hemodialysis. The data can be downloaded, exported, and edited at the same the while fully access to treatment data by effective using of blood volume monitoring data management system (BVMS), in order to achieve data analyzed by using information management system. Conclusion:by understanding the correlation betweenΔBV and blood pressure screen composition can help to speculate the reasons for drop in blood pressure;by combining the examination data can help to control dry weight management, by fully accessing to data can help to manage hemodialysis patient data information management system, and according to patients expression and display of blood volume monitoring to determine the appropriate amount of ultrafiltration, adjust dry weight and develop an appropriate treatment plan.
6.Study Progress in Apolipoprotein A-I's Gene Polymorphism and Its Relationship with Reverse Cholesterol Transport
Yi ZHANG ; Jing ZHAO ; Siyuan PAN
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(7):1649-1654
Apolipoprotein A-I (apoA-I) is a member of the apolipoprotein A family, which was discovered the earli-est. It has an important role in the regulation of lipid metabolism, which mainly includes cholesterol synthesis and transfer. Therefore, apoA-I is closely related to hyperlipidemia and atherosclerosis. Clinically, serum ApoA-I/ApoB has been used as one of the indexes of hyperlipidemia. This article reviewed the study progress in ApoA-I's gene polymorphism and its relationship with reverse cholesterol transport (RCT).
7.Effects of Sinomenine on Proliferation of Human Fibroblast-like Synoviocyte and Expression of MMP-3 mRNA from Patients with Rheumatoid Arthritis
Juan ZHANG ; Juan LI ; Yi ZHAO
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(03):-
Objective To observe the effect of sinomenine on the proliferation of fibroblast-like synoviocytes (FLS) and expression level of MMP-3 secreted by FLS in rheumatoid arthritis in vitro. Methods FLS were obtained by digesting synovial tissues with collagens and were divided into four groups:sinomenine high, middle, low concentration and control group. The proliferation of FLS was assessed by methyl- thiazolyl-tetrazolium (MTT) assay and the mRNA expression of MMP-3 was measured by semi-quantitative RT-PCR respectively after treated by sinomenine. Results The rate of FLS proliferation was significantly reduced in groups treated by sinomenine. Compared with control group, the mRNA expression of MMP-3 markly decreased in sinomenine groups (P
8.Laparoscopic Hernioplasty using Autologous Tissues for Inguinal Hernia in Adults
Yi PENG ; Yanlong ZHAO ; Fengtao ZHANG
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To explore the feasibility of repairing and strengthening the posterior wall of the inguinal canal with laparoscopic hernioplasty using autologous anterior abdominal wall tissues.Methods From January 2001 to September 2007,173 adult patients with inguinal hernia(141 cases of indirect hernia,28 cases of direct hernia,3 cases of femoral hernia,and 1 case of obturator hernia)were treated by laparoscopic hernioplasty with autologous tissues obtained from the median,internal,and lateral umbilical folds,and the U-shape fold.Three trocars were used to perform the laparoscopy by one surgeon,who completed the intracavity suturing using two hands.Results All the 173 operations were completed without converting to open surgery.Among the 152 cases of unilateral hernia,the mean operation time was 25 min(10-40 min),while in the 21 cases of bilateral hernia,the mean operation time was 40 min(20-60 min).Postoperative complications included retroperitoneal hematoma(1 case),scrotal swelling(3),testicular hydrocele(1),subcutaneous hemorrhage at the inguinal area(2),and scrotitis(1).The patients were followed up for 1-84 months(mean 35 months),during which 3 patients had recurrence.Conclusions Laparoscopic hernioplasty with autologous tissues is feasible and safe for adult patients with inquinal hernia with advantages of short hospitalization,minimal surgical trauma,quick recovery,and low rate of recurrence.
9.Clinical Application of Radiofrequency Ablation Technology in Treatment of Meniscus Injury Under Arthroscopy
Yi ZHANG ; Xinjian ZHAO ; Jianshao TAN
Journal of Chinese Physician 2001;0(06):-
Objective To investigate the efficacy of radiofrequency ablation in the treatment of meniscus injury. Methods 42 cases of damaged meniscus of knee joint were treated with radiofrequency ablation under arthroscopy. Results After 15 to 30 months(mean 25.2 months) follow-up, 38 knees ( 90%) were evaluated as excellent, and 4 (10%) as good. Conclusion Radiofrequency ablation was a safe, simple and effective technology for the treatment of meniscus injury of knee joints.
10.Application of sub-anesthetic doses of ketamine and fentanyl assisted regional anaesthesia
Jianli ZHANG ; Yi ZHOU ; Dongyin ZHAO
Chinese Journal of Primary Medicine and Pharmacy 2013;20(8):1178-1180
Objective To observe the clinical effect and safety of subanesthetic doses of ketamine and fentanyl assisted regional anesthesia.Methods 90 children received abdominal operation or limbs operation were selected in our hospital.They were randomly divided into A,B and C group with 30 children in each group.The children in group A received sub-anesthetic doses of ketamine and fentanyl in nerve block anesthesia; the children in group B received sub-anesthetic doses of ketamine and fentanyl anesthesia aided;while the children in group C accepted traditional ketamine anesthesia.The indexes of respiratory frequency,mean arterial pressure,heart rate and oxygen saturation and other basic vital signs as well as anesthesia adverse events of situation were compared.Results The respiratory frequency,mean arterial pressure and heart rate in group A and B were lower than those in group C,the difference was statistically significant(all P <0.05),whereas no difference was observed on the oxygen saturation between two groups(P >0.05).The respiratory rate,mean arterial pressure and heart rate in group A and B showed no significant difference (all P > 0.05).In adverse reactions,the muscle relaxants was in good condition in group A and B,no obvious body movement and gastrointestinal adverse events observed either.Group C with muscle relaxants in good condition,but body movement and some gastrointestinal adverse reaction can be observed occasionally.Conclusion Subanesthetic doses of ketamine and fentanyl has good anesthetic effect on regional anesthesia,and can effectively reduce the occurrence of adverse reactions,which is worthy of clinical application.