2.Fixation of displaced proximal humeral fractures with proximal humeral internal locking plate in the elderly
Quan JI ; Liangyuan WEN ; Qingyun XUE ; Lilian ZHAO ; Gongyi HUANG
Chinese Journal of Geriatrics 2011;30(9):749-752
Objective To investigate the treatment effect of the proximal humeral internal locking system (PHIL()S) on the elderly patients with displaced proximal humeral fractures.MethodsFrom Feb 2004 to Mar 2007, 36 patients (mean age: 72.2 years) with proximal humeral fractures were treated with PHILOS plate fixation which included 14 cases with 2-part, 17 cases with three-part and 5 cases with four-part fractures according to Neer classification.Operation time,intraoperative blood loss, blood transfusion, perioperative complications and function evaluation of the operated shoulder joint were calculated with 14.5 months follow-up at average.Results The average operation time and blood loss were (61.5± 11.6) min and ( 165.2±91.2) ml, respectively. 1 case with accidents of blood vessel and 1 case with pneumonia were found without neurovascular injuries. All fractures were radiographically healed in an average of 3-5 months.No necrosis of humeral head appeared and 30 (83.3%) cases were excellent or good according to Neer scoring system. Two part fracture and early operation ( within 3 days after operation) might improve the postoperative function of shoulder joint, but the patient's age, gender and ASA score were not statistically with Neer score.Conclusions PHILOS plate fixation is a suitable procedure for displaced proximal humeral fractures via stable fixation and early rehabilitation, especially for elderly patients combined with osteoporosis.
5.A clinical study on the influence of the fish oil fatty acid actting on the cellular immune and inflammatory response of perioperative patients of gastrointestinal tumors
Jianqiang HUANG ; Quan ZHENG ; Jianhui ZHAO ; Kuncai ZHENG
Chongqing Medicine 2013;(35):4289-4291
Objective To investigate the influence of the fish oil fatty acid (rich in ω-3 polyunsaturated fatty acids ) acting on the cellular immune and inflammatory response of perioperative patients of gastrointestinal tumors .Methods 79 gastrointestinal tumors patients who took total parenteral nutrition (TPN)after operation are divided into 2 groups randomly(collected from July 2010 to June 2012) .39 patients in study group are supplied with fish oil fatty acid within 24 h after operation and 7 d in total .40 pa-tients in the control group are supplied with ordinary long chain fat emulsion within 24 h after operation ,7 d as a course .The per-centage and the ratio of T lymphocyte subsets(CD3 ,CD4 ,CD8) ,monocyte human leukocyte antigen DR(HLA-DR) expression(per-centage) and the number of monocytes of 2 groups were test by blood test at 1st and 8th day after operation .Results The ratio of CD3、CD4、CD8、CD4/CD8 ,monocyte(HLA-DR) expression(percentage) and the number of monocytes in the study group were sig-nificantly higher than that of control group after received fish oil fat emulsion (P<0 .05) .There was no significant difference be-tween two groups on the 1st day after operation of C reactive protein (CRP) ,interleukin-1β(IL-1β) ,IL-6) ,IL-2 and IL-12(P>0 .05) .However ,compared with their results shown that they all had obvious difference respectively by a eight-day observation(P<0 .05) .compared with the first day the CRP in the control group at 8th day after operation were significantly higher than that of the 1st day ,the study group at 8th day was obviously decreased ,the difference was statistically significant (P<0 .05);IL-1βand IL-6 of the two groups were decreased at 8th day after operation and the study group decreased more obviously than the control group (P<0 .05) .IL-2 and IL-12 of the 2 groups at 8th day after operation were decreased than that of the 1st day ,but the difference between the two groups was not statistically significant (P>0 .05) .Conclusion Given the fat emulsion of fish oil which is rich in ω-3 poly-unsaturated fatty acid can significantly improve the cellular immune function of postoperative patients and release the inflammatory response after operation in patients of gastrointestinal tumors .
6.Cerebral fMRI study of the normal adult on electro-acupuncture Guangming point (GB37) under the vision stimulation condition
Quan ZHOU ; Peng GAO ; Canghuan ZHAO ; Xinjie HUANG ; Jie LI
Chinese Journal of Pathophysiology 1989;0(05):-
AIM:To study the human brain hemodynamics responses induced by acupuncturing foot shaoyang gallbladder meridian point GB37 and visual stimulation,and to analyze the effect of acupuncture to activate the cerebral functional area in visual stimulus. METHODS:Twenty five normal subjects were divided into two groups:15 subjects for electro -acupuncture GB37 in visual stimulus group and 10 subjects for electro-acupuncture GB37 groups. The blood oxygen level dependent functional magnetic resonance imaging (BOLD-fMRI) was carried out under the condition of two dif-ferent stimulation patterns (including a vision stimulation task and point GB37 acupuncture under the vision stimulation condition). A scintillating chessboard grid was applied as the vision stimulation task and the frequency was 8 Hz. The activation of cerebral functional areas of tested people under the conditions of the vision stimulation task and acupuncture were analyzed,respectively. RESULTS:Out of 15 subjects of electro -acupuncture GB37 in visual stimulus groups,twelve health volunteers were enrolled. When the vision stimulation task was carried out,the alarge area of brainstem and posterior lobe of cerebellum was seen to be activated. The areas of limbic lobe,hippocampus,middle temporal gyrus and inferior temporal gyrus were also activated. Under the condition of acupuncture only,the areas of posterior central gyrus,inferior parietal lobule,parietal lobe precuneus and the middle frontal gyrus were activated. When doublesided points of gallbladder meridian of foot-shao-yang were electroacupunctured under the visual stimulus status,the areas of superior frontal gyrus,inferior frontal gyrus,parietal precuneus and occipital gyrus lingualis were activated. CONCLUSION:The functional MRI shows the activation of cerebral functional area after acupuncture. Visual stimulus causes significant changes of brain conduction path connection. Under the visual stimulus status,the acupuncture to the points of gallbladder meridian of foot -shao -yang,GB37 has an extent of influence to conduction path conformity of the vision system and with the treat-ment of ophthalmocace. Furthermore,the external stimulation has prominent influence to the acupuncture therapy possibly.
7.Clinical features of and therapeutic analysis on 54 transferred patients with open injuries combined with infection in Chinese Wenchuan earthquake
Minpeng LU ; Dianming JIANG ; Zhengxue QUAN ; Wei HUANG ; Weidong NI ; Zenghui ZHAO ; Hong CHEN
Chinese Journal of Trauma 2008;24(9):763-765
Objective To analyze the clinical features of patients with open injuries combined with infections in Chinese Wenchuan earthquake and summarize the therapeutic experience. Methods An analysis was done on 54 patients with open injuries combined with infection transferred to our depart-ment from May 13, 2008 to June 10, 2008. Thorough debridement was performed based on general sup-porting management and anti-bacterial thempies done on the basis of results of bacteria culture and sus-ceptibility test. In the meantime, other managements including high-pressure oxygen therapy and external fixation were done for open fractures. Results Infection could be found in all open injuries, primarily combined infections with G+ coccus and G- bacillus or anaerobic. Moreover, most of the patients were infected by anaerobia. Of all, 1 patient with amputation received multiple debridement and repair because of severe infection of the amputation site and no death occurred. All patients recovered uneventfully, with sound wound healing, except for 2 patients. External fixation was stable and in good position. Conclu-sions The repeated and thorough debridement and the timely closure of wounds on the basis of energeti-cally anti-infection measures are key to diminishing the mortality rate and mutilation rate. Appropriate ad-junctive therapy can dramatically improve the curative effect.
8.Methods of HPV detection in exfoliated cells and tissue specimens approved by the United States Food and Drug Administration.
Cheng-quan ZHAO ; Huai-tao YANG ; Zhi-dan TIAN ; Wen-bin HUANG
Chinese Journal of Pathology 2012;41(12):855-857
Cervical Intraepithelial Neoplasia
;
diagnosis
;
virology
;
DNA, Viral
;
isolation & purification
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Female
;
Human papillomavirus 16
;
genetics
;
isolation & purification
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Human papillomavirus 18
;
genetics
;
isolation & purification
;
Humans
;
Molecular Diagnostic Techniques
;
methods
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Papillomaviridae
;
genetics
;
isolation & purification
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Papillomavirus Infections
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diagnosis
;
virology
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RNA, Messenger
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metabolism
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United States
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United States Food and Drug Administration
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Uterine Cervical Neoplasms
;
diagnosis
;
virology
9.Correlation between p53 gene mutations and p53 protein overexpression in esophageal squamous cell carcinoma.
Guang LI ; Zhao-xia LIU ; Jing HUANG ; Jun-mei WANG ; Quan-hong WANG
Chinese Journal of Pathology 2005;34(12):802-804
Adult
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Aged
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Carcinoma, Squamous Cell
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genetics
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metabolism
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Esophageal Neoplasms
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genetics
;
metabolism
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Female
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Gene Expression Regulation, Neoplastic
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Genes, p53
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Humans
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Loss of Heterozygosity
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Male
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Middle Aged
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Point Mutation
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Tumor Suppressor Protein p53
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genetics
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metabolism
10.Anomalous origin of the right coronary artery from the left coronary sinus of valsalva with an interarterial course: dual-source CT evaluation
Longjiang ZHANG ; Guangming LU ; Wei HUANG ; Changsheng ZHOU ; Peng CHEN ; Yane ZHAO ; Quan LIANG
Chinese Journal of Radiology 2009;43(9):938-941
clues for interpretation of myocardial ischemia.