ObjectiveTo investigate the correlation between the surgical effect and clinical factors in retinal detachments with macular hole patients.Methods71 patients were picked up from the rhegmatogenous retinal detachment (RRD) database in our hospital. All patients were well informed with clinical data and followed up. Logistic regression statistical analysis was performed to analyze correlation between the effect of operation and clinical factors.ResultsAll patients obtained successful retinal replacement and macular hole closure, but retinal detachment was relapsed in 10 patients from 3 days to 3 years after operation. Effect of retinal replacement was related with proliferative vitreoretinopathy (PVR) grade and course (P<0.05), while eyesight improvement was related with PVR grade, age and course (P<0.05).ConclusionAge, PVR grade and course affect the surgical effect.

Objective: To study the effective treatment methods of arteriovenous malformation(AVM) in jaw bone through retrospective review. Methods:33 patients with jaw AVM were analyzed by history, treatment methods and outcome. Results: Among the 33 patients 6 were treated by embolization only, 12 by curretting, 10 by resection of the bone lesions. The cure rate in the three groups was 2/6,11/12 and 10/10 respectively. Conclusions: Embolization combined with curretting may be the effective methods to treat facial bone AVM without resection of bone.

Objective: To compare the expression of multidrug resistant gene( mdr 1 ) in oral squamous cell carcinoma (SCC) before and after chemotherapy. Methods: Mdr 1 gene expression in 21 cases of oral SCC was detected before and after chemotherapy by dot blot hybridization, Results: Before and after sigle drug chemotherapy mdr1 mRNA(?10 5 copies/?g) in SCC tissue was 1.98?1.72 and 3.74?3.24( P

Clinical data of 28 cases of childhood bronchiolitis obliterans treated from September 2008 to November 2010 were retrospectively analysis.Pulmonary high-resolution CT (HRCT) showed that bronchial wall thicken was seen in all 28 patients,the mosaic pattern in 26 cases,patchy shadows in 18 cases,bronchiectasis with typical signet ring sign in 2 cases,atelectasis in 2 cases without pleural effusion.Pulmonary function tests and flexible bronchofiberscopy were performed in 6 cases,which showed the inflammation in bronchial tunica intima and obstruction of small airway.Blood routine,blood sedimentation,c-reaction protein,TORCH,hepatic function,renal function and immune function were normal.Patients received comprehensive treatment with methylprednisolone,clarithromycin and montelukast.The clinical conditions of 28 cases were improved with varying degrees after treatment and no significant side effects were observed.

Objective To observe the effect of Yiqi Huoxue TCM combined with L-OHP+CF+5-FU regimen in treating advanced colorectal cancer patients. Methods 68 advanced colorectal cancer patients were randomly assigned to treatment group (38 patients, treated by Yiqi Huoxue TCM combined with L-OHP+CF+5-FU) and control group (30 patients, treated with L-OHP+CF+5-FU regimen). The therapeutic effects of two groups were observed. Result Clinical beneficial rate (CR+PR+SD) of treatment group and control group were 78.9% and 53.3% respectively (P

Objective: To investigate the prevalence of Internet addiction among primary and middle school students in Jiaxing City, so as to provide insights into the development of interventions for Internet addiction among primary and middle school students. Methods: A total of 1 701 students were sampled from two primary schools, two junior high schools, two senior high schools and two vocational high schools in Jiaxing City during the period between September and October, 2021, using the stratified cluster sampling method. The Internet addiction status was evaluated using the Internet Addiction Test, and the depression status was tested using the Patient Health Questionnaire-9 (PHQ-9), while the anxiety was assessed with the Generalized Anxiety Disorder Scale (GAD-7). Results: The participants included 783 men (46.03%) and 918 women (53.97%), and 873 rural students (51.32%) and 828 urban students (48.68%). The overall detection of Internet addiction was 6.53% among the participants, and the prevalence of moderate and severe Internet addiction was 5.88% and 0.65%, respectively. A higher prevalence of Internet addiction was detected in rural students (χ2=4.695, P<0.05), junior high school students (χ2=65.337, P<0.05), students with a poor relationship with family members (χ2=39.231, P<0.05), teachers (χ2=28.799, P<0.05) and classmates (χ2=36.341, P<0.05). The prevalence of depressive and anxiety symptoms was 23.81% and 21.52%, respectively, and the prevalence rates of depressive and anxiety symptoms were both higher among primary and middle school students with Internet addiction (68.47% and 56.76%) than among those without Internet addiction (χ2=130.556 and 87.327, both P<0.05). Conclusion The prevalence of Internet addiction is high among primary and middle school students living in rural areas and with poor interpersonal relationships in Jiaxing City. Students with Internet addiction are more likely to develop depressive and anxiety symptoms.

Objective:To study the relationship between preoperative serum carbohydrate antigen 19-9 (CA19-9) levels and long-term prognosis after partial hepatectomy in patients with hepatocellular carcinoma (HCC).Methods:The clinical data of 1102 patients with HCC who underwent partial hepatectomy at the Affiliated Tumor Hospital of Guangxi Medical University from January 2012 to December 2017 were retrospectively analyzed. There were 960 males and 142 females, with an average age of 51 years. The X-tile software determined the best cut-off value of CA19-9 to be 55U/ml. The enrolled patients were then divided into the low-level (CA19-9≤55 U/ml, n=956) and high-level (CA19-9 >55 U/ml, n=146) groups. The Kaplan-Meier method was used to analyze survival, and the log-rank test was performed to evaluate survival rates. The prognostic risk factors of HCC were calculated by the Cox proportional hazards model. Results:The 1, 3, and 5-year survival rates for the low-level group were 85.0%, 68.2%, and 60.9%, respectively, which were significantly higher than those of the high-level group of 80.1%, 58.2%, and 47.0%, respectively ( P<0.05) . The 1, 3, and 5-year recurrence-free survival rates of the low level group were 60.5%, 44.6%, and 37.9% respectively, which were significantly higher than those in the high-level group of 53.4%, 33.3%, and 25.1%, respectively ( P<0.05). Cox regression analysis showed that patients with CA19-9 >55 U/ml ( HR=1.323, 95% CI: 1.070-1.636, P=0.010) had a higher risk of recurrence after hepatectomy, while patients with CA19-9 >55 U/ml ( HR=1.511, 95% CI: 1.163-1.964, P=0.002) had a poor prognosis after hepatectomy. Conclusions:Preoperative serum level of CA19-9>55 U/ml was an independent risk factor for survival and recurrence of HCC patients after partial hepatectomy. CA19-9 had a significant predictive value for prognosis of HCC patients who underwent partial hepatectomy.

Objective To investigate experience in adult inguinal hernia treated with the open preperitoneal herniorrhaphy.Methods Eight hundred and twenty-six cases were retrospectively analyzed from February 2004 to December 2011 in our hospital.The effect of operative methods and treatment were observed simultaneously.Results All the patients were cured completely without special complications; Followed up for 12 months,some negative factors such as incision infection,recurrence,special discomfort,and chronic pain have not been appeared.Conclusions The open preperitoneal herniorrhaphy under local anesthesia for adult inguinal hernia is safe,reliable and effective.

Objective To understand the status quo of AIDS discrimination among Xinjiang medical college students and its influence factors .Methods By using the stratified cluster sampling method ,583 students in a Xinjiang medical college were conduc‐ted the AIDS related questionnaire investigation .Results If medical undergraduate students found that the schoolmates carried HIV ,18 .01% of college students would not directly contact with them ,45 .97% of medical college students would not give sympa‐thy and concern ,31 .22% of students would not keep normal communication with them ,53 .17% of medical college students thought that they should drop out of school to go home ,32 .76% of medical college students would not keep a secret to the outside world ;40 .99% of the medical college students would advise them to restrain their own behaviors ,24 .87% of medical college students would choose to report it to the teacher or leader .By the multivariate analysis of covariance ,gender ,nationality ,family monthly in‐come ,origin of students ,AIDS related knowledge ,etc .were the factors affecting the level of AIDS discrimination .Conclusion The medical college students have a certain degree of discrimination to the AIDS patients ,learning the AIDS related knowledge should be strengthened for reducing the fear psychology on AIDS ,thus to eliminate the discrimination towards AIDS .