2.Rescue and treatment of 18 cases of acute paraquat poisoning.
Jing-li ZHAO ; Jian-shun ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2010;28(2):109-109
Adult
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Aged
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Female
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Herbicides
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poisoning
;
Humans
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Male
;
Middle Aged
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Paraquat
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poisoning
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Poisoning
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therapy
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Young Adult
3.Qualitative research on status of residents' living condition in Third Grade Class A hospitals in Beijing
Guangyuan JIAO ; Meng ZHAO ; Jian ZHANG
Chinese Journal of Medical Education Research 2017;16(2):189-193
Objective By exploring the state of residents' living condition, it is helpful to promote the living condition of residents and improve the quality of medical services. Methods A qualitative re-search was conducted on 13 residents in 4 hospitals in Beijing by depth interview during April to May 2016, and the data were collected and analyzed by using Colaizzi seven step method. Results In terms of work, the residents had specific work, and the interpersonal relationship was more harmonious. In learning, residents were able to take the initiative to learn, and hoped to get more help in scientific research. In life, residents faced multiple pressures from the economy and the family. In the subjective cognition, the cogni-tion of resident was rational and objective. Conclusion The residents' work shows a heavy workload, and while working the residents need to take the study and the life pressure into account. And the residents can rationally recognize their role. To improve the living status of the resident physician, we need to integrate multiple forces, to promote the integration of live doctors into the hospital culture, and enhance their sense of existence. We also need to improve the construction of the system and improve the protection of live training physicians to enhance their sense of security. Most important of all, the whole society should pay more attention to the living condition of the residents and enhance their sense of access.
4.CMH IS THE MULTIDRUG RESISTANCE(MDR) ASSOCIATED NEUTRAL GLYCOSPHINGOLIPID IN KBv_(200)CELL LINE
Jian ZHANG ; Senming WANG ; Yan ZHAO
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
In order to study the relationship between the expression of neutral glycosphingolipids(N-GSLs) and MDR, N-GSLs in MDR cell line KBv 200 and its parental cell line KB were studied. The N-GSLs were extracted and purified from the KB and KBv 200 cells according to the modified method of Hakomori, then analysed by High Performance Thin Layer Chromatography (HPTLC). The effects of PPMP on the expression of N-GSLs in KBv 200 cell line were also studied by the above method, its reversion on the KBv 200 cells to Vincristine (VCR) was examined by MTT method. The results showed that the levels of CMH and CDH in KBv 200 cells were higher than in KB cells, CMH was much more markedly increased, PPMP could reverse MDR by inhibiting CMH synthesis. It suggested that CMH is MDR associated N-GSLs in KBv 200 cell line, and inhibition of CMH expression in tumor cells maybe a new way to reverse MDR.
5.Establishment of a real-time fluorescence quantitative RT-PCR for measurement of t-PA mRNA expression in endothelial cells
Yanting ZHAO ; Lianfen ZHANG ; Jian JIN
Chinese Pharmacological Bulletin 1986;0(05):-
0.990).The intra-assay and inter-assay variation of the method was 3.10 % and 4.93 %,respectively.The all-trans ratinoic acid(ATRA) up-regulated t-PA mRNA expression in a dose-dependent manner(1.25~20.00 ?mol?L~(-1),P
6.Biomechanical study of single - level anterior cervical intervertebral decompression and fusion with plating uniplate and orion
Feng ZHANG ; Jianhua LU ; Jian ZHAO
Orthopedic Journal of China 2006;0(19):-
0.05).[Conclusion]The stability of the single - level anterior cervical intervertebral decompression and fusion with plating Uniplate is satisfactory.Uniplate is valuable in clinic,furthermore,it is relatively simple to operate.
7.Research on dynamic three-dimensional reconstruction of tissue doppler ultrasound heart images
Wenlan ZHANG ; Kehui ZHAO ; Jian LI
China Medical Equipment 2014;(4):60-62
Objective:To discuss the dynamic three-dimensional reconstruction of tissue Doppler ultrasound cardiac image.Methods: To separate anatomical structure and function parameter information from Doppler ultrasound medical image, and then combines with the three-dimensional distribution to reconstruct it and fuse imaging.Results: Ultimately, it reveals the relationship between function parameter and anatomical structure. The dynamic three-dimensional reconstruction of tissue Doppler ultrasound cardiac image is also expounded in this paper.Conclusion: It scientifically completed the dynamic three-dimensional reconstruction of tissue Doppler ultrasound cardiac image by combining both tissue Doppler imaging and ultrasound medical image reconstruction technique. It is of great significance in clinical medicine.
8.Follow-up analysis of MRCP in 116 patients with obstructive jaundice
Jian LI ; Wenlan ZHANG ; Lihua ZHAO
Chongqing Medicine 2015;(15):2062-2064
Objective To evaluate the application value of magnetic resonance cholangiopancreatography (MRCP) in the pa‐tients suffering from obstructive jaundice .Methods 126 patients diagnosed as obstructive jaundice underwent the abdominal MRCP examination and MRI scanning .The diagnostic results were recorded and the follow‐up observation was persisted .The MRCP diag‐nosis results were compared with the pathological or ERCP results obtained by follow up .Results Comparing the MRCP diagnostic results with the follow up results ,the coincidence rate of location diagnosis was 100% .The MRCP and follow up results in the qual‐itative diagnosis had no statistically significant difference .M RCP had the higher sensitivity ,specificity ,positive value and negative value in the judgement of different causes of obstruction .Conclusion M RCP has the higher accuracy for the qualitative and location diagnosis of obstructive juandice and also has the higher diagnostic value for judging the different obstructive causes .
9.Treatment strategies for patients with negative biopsy for pancreatic head mass
Taiping ZHANG ; Jian LI ; Yupei ZHAO
Chinese Journal of Hepatobiliary Surgery 2012;(11):809-812
The special anatomy around the head of pancreas leads to difficulties in arriving at a definitive diagnosis for a pancreatic head mass,the management of which has recently become a hot topic and a challenge for clinicians.Despite recent advances in tumor markers,ultrasound,CT,PET/CT and MRI,some of these pancreatic head masses cannot be diagnosed with certainty.A fine needle aspiration biopsy can be used before operation; however,false negative results not infrequently happen.Based on the reports from domestic and foreign medical literatures published recently,this paper reviewed and discussed the proper treatment strategies when biopsy results from a pancreatic head mass turn out negative.
10.Construction of tissue-engineered blood vessel stent using different materials: Characteristics and effectiveness
Mingdi YIN ; Zhengkai ZHAO ; Jian ZHANG
Chinese Journal of Tissue Engineering Research 2010;14(16):2958-2962
OBJECTIVE: To evaluate the characteristics and application prospect of tissue-engineered blood vessel stent materials. METHODS: Using "tissue engineering, tissue engineering blood vessel, intravascular stent" both in Chinese and English as key words to search documents published between January 1993 and October 2009. Literatures concerning biomaterials and tissue engineered blood vessel were included. Repetitive research or Meta analysis was excluded. After selection, 30 documents were included to discuss the kinds and characteristics of tissue-engineered blood vessel materials. RESULTS: Cellular tissue matrix is a kind of ideal material for intravascular engineering, which had widely applied in tissue-engineered stent. The fibrin-based stents are characterized by good biocompatibility, biodegradation, compatibility, as well as promote vascularization and tissue repair. Gelatin can implement its own "vascularization" due to less antigenicity and can be fully biodegraded. Accordingly, both the natural biomaterials and synthetic polymeric material have certain limitations, thus, the combination of these two materials would construct a tissue-engineered blood vessel stent that has good characteristics.Nano-modifled technology is hopeful to be applied in the future transplantation of tissue-engineered blood vessel stent.CONCLUSION: The tissue-engineered blood vessel developed rapidly in these years. However, as yet, there is not an ideal intravascular stent material. The natural biomaterials arose more attention, but the mechanical function of which is far from the stent requirement. Thus, to reach the aims of repair and reconstruction, new materials are the urgent need in tissue-engineered intravascular stent.