Objective To investigate the influence of early postoperative enteral nutrition on the immunologic function and inci-sion infection in the patients with colorectal cancer .Methods 81 postoperative cases of colorectal cancer were randomly divided into the early parenteral nutrition(41 cases) ,and the early enteral nutrition(40 cases) by the random number table method .The anal ex-haust time ,ambulation time and occurrence situation of incision infection ,etc .were compared between the two groups ,and the im-munological indexes changes were also compared .Results Postoperative anal exhaust time ,bed activity time and the occurrence rate of incision infection in the early enteral nutrition group were significantly lower than those in the early parenteral nutrition group (P<0 .05);Th1/Th2 and lymphocyte count in the early enteral nutrition group were significantly higher than those in the early parenteral nutrition group(P<0 .05) .Conclusion The early postoperative enteral nutrition support in the patients with colorectal cancer can effectively improve the body's immune function and is an ideal method of nutritional support .

Presently,studies of onset,development and tumor drug resistance of osteosarcoma were few.Further studies on tumor animal models can provide a promising basis for treating osteosarcoma.Commonly used animal models of osteosarcoma include mouse,rat,rabbit and dog.Organs of rats are similar to human,so does genotype.Dogs can spontaneously develop osteosarcoma,which is similar to human,and are frequently used as spontaneous tumor models.However,there are some differences in biological features,pathogenic mechanism and histology.With the development of studying,there will be more and more new animal models in accordance with human osteosarcoma characteristics.The present study served to review methods of establishing models,characteristics and detailed application of animal models of osteosarcoma.

OBJECTIVE To improve the administrative and controlling quality of hospital acquired infection(HAI),practice all kinds of works of HAI and decrease the incidence rate of it.METHODS We should strengthen leading power,perfect constitution and administration web,make project workable,intensify education of HAI,improve all medical staff administrative consciousness and whole quality of professional people of HAI,reinforce precaution and manipulation,and erect system of informational feedback.RESULTS All kinds of works of HAI were improved and medical staff administrative consciousness of HAI was enhanced through administration,and we could ensure the effects of sterilizing and killing bacteria.CONCLUSIONS We could carry out all kinds of institutions of HAI through administrative system of standard-check-reward and punish.

Objective To observe and discuss the effect of using the self-made pressure reduction bilateral nasal oxygen tube to prevent the ear pressure sore for the comatose patients. Methods Totally 86 cases of comatose patients which needed permanent oxygen inhale admitted during Jan 2016 to Dec 2016 were divided into observation group and control group:Each group 43 cases. Observation group used self-made pressure reduction bilateral nasal oxygen tube to inhale the oxygen, control group used the conventional disposable bilateral nasal oxygen tube to inhale the oxygen and the pressure ulcer stage. Results There was no significant difference in Braden score in two groups, the difference was statistically significant (P>0.05) . Observed two groups patients′ nasal oxygen tube ear pressure sore situation, these were only 2 patients happened nasal oxygen tube ear pressure sore in observation group, on the contrary, these were 9 patients happened in control group, occulting probability was higher than observation group significantly. and the extend of the pressure sore is much serious than the observation. Difference was statistically significant (χ2=5.11, P<0.05). Conclusions During the privation of the nasal oxygen tube ear pressure sore for the comatose patients, self-made pressure reduction bilateral nasal oxygen tube can alleviate the ear skin pressure effectively, reduce the pressure sore occur, the effect is obvious, nursing quality is improved, deserve the clinical expansion.

Objective To analyse the effect of hedyotisdiffusa on expressions of apoptosis related protein Fas , caspase3 and caspase7 in Renca renal cell carcinoma of model mice.Methods One hundred and twenty BALB/C male mice were randomly divided into normal control group, model control group, interleukin group, hedyotisdiffusa group, 30 mice in each group, half male and female.Excepted for normal control group , renal cell carcinoma models were established in the other groups , and were given corresponding drug treatment.The tumor size and weight , and the tumor inhibition rate of all mice were observed, and the expression levels of Fas,FasL,caspase3 and caspase7 were detected.Results Compared with model control group, the tumor size and weight were lower , the tumor inhibition rate were higher , the positive expression rates and protein levels of Fas were higher , the positive expression rates and protein levels of FasL were lower, the positive expression rates and expression levels of Caspase3,Caspase7 protein were higher in the mice of interleukin group and hedyotisdiffusa group, all with significant differences ( P<0.05 ).The above indicators in hedyotisdiffusa group were significant improved compared with interleukin group (P<0.05).Conclusion The hedyotisdiffusa can effectively promote the expressions of apoptosis related protein Fas,caspase3 and caspase7 in renal cell carcinoma of model mice, inhibit the expression of FasL protein, improve the tumor suppression rate.

The aim of China National Medical Licensing Examination (CNMLE) is to check and assess examinee's requirement for medical practice. In a certain extent, the score result of Medical Licensing Examination reflects the examinee's mastery degree of knowledge, ability and skills (SAKs) learned in medical school. Through the subject diagnostic analysis on the Medical Licensing Examination for certain samples, this research reviewed the clinical medical student's mastery degree of different SAKs. The author wishes the conclusion of this paper would be helpful to some aspects of medical education.

With the application of gene editing in medical treatment,food engineering,environmental protection,agriculture and forestry,it gives rise to a wide range of potential social risks.Both the advanced aspects and defects of this technology bring complicated social conflicts.It is undoubtedly crucial to coordinate the conflict of interests of all parties,improve the legal system and avoid the harmfulness and blindness of gene editing.Meanwhile,only that the ethical,legal and social concerns are introduced will govern the technical risk as a necessary condition in order to attain a virtuous cycle of technological improvement and social prosperity.

the Purpose of spermatozoon storerooms are setting up for solving the sterile problem.But some storerooms are found for commercial aim such as the spermatozoon storeroom,for celebrities or doctors'.It should not be approved of.The reasons is that it conflicts with such concepts as life equality,ethical relationship among families,and option for sterile couples.We should prohibit the establishment of the spermatozoon storeroom for the commercial purposes.

Anticoagulation is one of the important approaches in the prophylaxis and treatment of iSCheroic stroke.However.it may increase the risk of bleeding events in reducing the risk of recurrent stroke at the same time.This article reviews the status of anticoagulants in the prophylaxis and treatment of ischemic stroke by retrospecting their application in the prevention and treatment of ischemic stroke and the study of new anticoagulants.

Vascular eognitive impairment (VCI) is a large class of syndromes from mild cognitive impairment to dementia, which are caused by the cerebrovascular risk factors (eg, hypertension, diabetes and hyperlipemia), obvious (eg, cerebral infarction and intracerebral hemorrhage) or unobvious cerebrovascular diseases (leukoaraiosis and chronic cerebral ischemia). Accurate early diagnosis provides the best treatment opportunity and slows down the progress of the disease. In recent years, the research on VCI has made a great progress. This article reviews VCI from the aspects of the etiology, clinical manifestation, neuropsychology, imaging, neuroelectrophysiology, biomarkers, and diagnostic criteria.