1.Cognitive processing of Chinese characters between hearing-disabled and normal people
Chinese Journal of Tissue Engineering Research 2005;9(12):234-235
BACKGROUND: At present, there are some researches on the cognitive identification of Chinese characters at home or abroad, however, most of them are based on the normal and healthy people.OBJECTIVE: To investigate the processing styles of optical information on phonemic code, graphic code and semantic code of Chinese haracters between hearing-disabled and normal people.DESIGN: Retrospective, observational and compared analysis based on the hearing-disabled as research subjects and the normal as the controlled group.SETTING: Department of education in a university.PARTICIPANTS: This study was completed in Xi' an between October 2001 and April 2002. With the mean age of 17 years and half in gender, 20hearing-disabled people, who were in grade 6 to grade 8, were selected from the Second School for the Deaf and Dumb in Xi' an. Inclusion criteria: The hearing loss of people was more than or equal to 92 dB. Exclusion criteria:People with acquired hearing-disabled were excluded. At the beginning of study in primary school, they were accepted oral training and taught Chinese pinyi, but gesture was the main communicated style in their daily life. With the mean age of 15 years and half in gender, 28 normal people, who were in grade 3, were selected from the No. 99 Middle School in Xi'an.METHODS: This study showed with serial opticum. The diagnostic method was compared with the cognitive identification of the three kinds of Chinese characters between the hearing-disabled and the normal respectively.phonemic code, graphic code and semantic code between hearing-disabled characters between hearing-disabled and normal people.RESULTS: The results showed that the function of graphic code in visual processing was strongly correlated with recognition of words of Chinese characters than the phoneme code and semantic code in both the hearing-disabled and hearing children. For hearing-disabled children, the alternative was the direct access that a semantic code was produced directly from a translation of the graphic code, however, the hearing children used the strategies of grapheme-phoneme conversion rules to interpret the meaning of words.CONCLUSION: The analysis of various results showe that no significant differences of mental processing are found between the hearing-disabled and hearing children. Perhaps both the direct access and the grapheme-phoneme conversion will be a comprehensive information processing activated each other.
2.Characteristics and diagnostic value of fundus fluorescein angiography for familial exudative vitreoretinopathy
Chinese Journal of Ocular Fundus Diseases 2011;27(3):263-266
Objective To investigate the characteristics and diagnostic value of fundus fluorescein angiography(FFA)for familial exudative vitreoretinopathy(FEVR).Methods 34 children(68 eyes)with FEVR and 64 parents(1 28 eyes)were included.All the clients were received examinations of slit-lamp biomicroscopy and indirect ophthalmoscopy.Meanwhile the children were examined by Retcam Ⅱ,the best corrected visual acuity of parents were recorded.The children and their parents were classified according to the ocular findings.Among 68 eyes of children,3 eyes(4.41% )were normal,4 eyes(5.88% )were in stage 1,7 eyes(10.29% )were in stage 2,2 eyes(2.94% )were in stage 3,8 eyes(11.76% )were in stage 4 and 44 eyes(64.71% )were in stage 5.Among 128 eyes of parents,74 eyes(57.81% )were normal,51eyes(39.84% )were in stage 1,1 eyes(O.78% )were in stage 2 and 2 eyes(1.56% )were in stage 5.FFA was performed on the children with RetcamⅡunder anesthesia and on the parents with HR2 in order to observe the FFA characteristics in different stage.Results FFA characte ristics in children included uncompleted vascularization of the periphery,peripheral avascular zone(stage 1);neovascularization and/or peripheral subretinal and intraretinal exudation(stage 2);subtotal retinal detachment with attached foyea (stage 3);subtotal retinal detachment with detached foyea(stage 4)and total retinal detachment(stage 5).FFA characteristics in parents included abrupt cessation of the peripheral retinal capillary network and a peripheral avascular zone(stage 1); abnormal peripheral arteriovenous shunts, neovascularization or exudation(stage 2)and atrophia bulbi(stage 5).Conclusions FEVR in different stage has different FFA characteristics.FFA plays an important role in early diagnosis of FEVR.
3.Effects of propofol and isoflurane anesthesia on serum heat shock protein 70 of perioperative patients with traumatic brain injury
Huapeng ZHANG ; Guangzong ZHAO
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(1):35-36
Objective To investigate the effect of propofol and isoflurane anesthesia on serum heat shock protein 70 ( HSP70 ) of perioperative patients with brain injury and compare the anesthetic effect of the two narcotic drugs. Methods 30 patients with medium or severe traumatic brain injury,treated by hematoma evacuation operation,were randomly divided into propofol ( n = 15 ) and isoflurane group ( n = 15 ). After anesthesia induction,propofol (target effect concentration of 3 ~ 4 μg/ml ) was intravenously injected and 1.2% isoflurane was inhalated into the patients of the 2 groups,respectively. In addition,vecuronium and fentany were intermittent intravenously injected into patients to maintain the depth of anesthesia. HSP70 in blood of patients were detected before anesthesia induction, 1 h after the dura was opened and 24 h after the operation by ELISA method. Recovery and tracheal extubation time of patients were recorded. Results HSP70 levels in blood of patients in the 2 groups were significantly increased compared with the former time point(P<0.05 ). HSP70 content in propofol group was significantlyhigher at 1 h after the dura was opened( ( 2.00 ± 0. 24 ) ng/ml, ( 2.19 ± 0.26 ) ng/ml, t = 2. 080, P = 0.047 ) and 24 h after the operation( t=2.086, P=0.046) ,and recovery and tracheal extubation time was shorter compared with the isoflurane group(P<0. 05). Conclusion Perioperative moderate stress,and early postoperative recovery and extubation can be maintained in patients with traumatic brain injury with profol anesthesia.
4.Clinical analysis of 21 cases of pediatric bridging bronchus
Journal of Clinical Pediatrics 2014;(3):242-245
Objective To explore the clinical diagnosis and treatment of pediatric bridging bronchus deformity and brid-ging bronchus with pulmonary artery sling. Methods The clinical data of the 21 cases of diagnosed bronchial bridge deformity and bronchial bridge with pulmonary artery sling, the imaging findings of all the echocardiography, MSCT chest scan, enhanced CT and reconstructive image were retrospectively analyzed. Results In 21 cases, 10 were diagnosed as bronchial bridge only, among which three cases had other types of congenital heart disease;11 cases were diagnosed of pulmonary artery sling with pulmonary artery sling, among which 8 cases had other types of congenital heart disease;their average age of the 8 cases were all younger than 2 years old, except one case;most of them had the symptoms of recurrent respiratory tract infections and parox-ysmal dyspnea. According to Wells, bronchial bridge was divided into type I and typeⅡ;15 cases were type I, 6 cases were typeⅡ, 10 patients with bronchial bridge only were all type I, 5 cases of typeⅡwere associated with pulmonary artery sling. All of the 6 cases were diagnosed as typeⅡassociated with pulmonary artery sling. Conclusions Infants and young children with clini-cal recurrent respiratory tract infections should be considered the possibility of bronchus bridge deformity, and should be paid more attention to the possibility of pulmonary artery sling. MSCT plain chest scan, enhanced CT and airway reconstructive im-age are the important ways to diagnose the disease.
5.Development of the group intelligence scale for military personnel ( Part B)
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(8):754-756
ObjectiveTo develop the group intelligence scale for Military Personnel ( Part B),and examining its reliability and validity of the scale.MethodsFollowing the intellectual shock theory,crystal and fluid intelligence theory,the group intelligence Scale for Military Personnel (Part B) had been constructed,which including two subscales,each subscale was divided into two subtests.The data was collected in 1200 military personnel who were chosen by random cluster sampling,then employing SPSS17.0 and AMOS7.0 for item analysis,reliability and validity,analysis of confirmatory factor.Resultsthe subtests' average index of difficulty was 0.55 ( 0.42 ~0.75 ) ; Discrimination index was 0.44 (0.33 ~ 0.52) ; the test-retest reliability between subtests and total scale ranged from 0.796 to 0.891 ; Cronbachs'a coefficient ranged from 0.619 to 0.892; and the split-half reliability ranged from 0.538 to 0.844; exploratory factor analysis revealed that four factors of the scale (including normal knowledge and generalizability,insight and word explain,picture completion and figure inference) could explain 59.067% of total variance.Furthermore,analysis of confirmatory factor indicated that the four factors model established in the present study fitted the sample data well.ConclusionThe item analysis,reliability and validity of the newly developed group intelligence scale for military personnel (part B) can meet the basic requirements of psychometrics.
6.Intracerebral image features of the patient with primary progressive aphasia: One case of nuclear magnetic resonance analysis
Chinese Journal of Tissue Engineering Research 2005;9(40):142-144
BACKGROUND: In clinic, primary progressive aphasia is a dementia syndrome with the only or prominent characteristic of progressive decline in language function. In advanced stage, deficit of cognitive capability and loss of daily living ability would turn up while memory ability would be relatively preserved. The risk factors of primary progressive aphasia might include poor language ability in childhood and speech center involved by brain trauma.OBJECTIVE: To report the intracerebral image features of 1 case of primary progressive aphasia so as to disclose the general lesion area of the disease , the changes of intracerebral blood volume and metabolism , and connecting fibers among the language domains.DESIGN: Case-report.SETTING: Department of Intervention, Hongqi Hospital, Mudanjiang Medical College, Hei Longjiang Province.PARTICIPANTS: 1 case of patient with primary progressive aphasia,male, 56 years old and with senior high school culture, was in business before the onset of disease. He had "progressive decline in language ability for 3 years" as the main complaint and was diagnosed in Department of Neurology of Beijing Tiantan Hospital on March 20th, 2004. 3 years before that time, the patient could not tell the name of daily living appliances while his comprehensive ability was generally normal. 2 years before, he could still be in business. 1 year before, his language disorder was aggravated, auditory and comprehensive abilities gradually decreased and the changes of character turned up while he could take care of himself and had no obvious degeneration in memory ability. Neural systemic examination: systolic pressure was 130 mmHg and diastolic pressure was 80 mmHg, with clear consciousness, poor language expression ability, and nomenclatural disability while no abnormity was inspected in other neural systematic examinations. He was assessed as sensory aphasia with normal memory and intelligence according to aphasia assessment measuring scale made by the First Hospital of Beijing Medical University.METHODS: First, general magnetic resonance examination was taken to fix the lesion area of the patient. Then, functional magnetic resonance was carried out, which mainly included using magnetic resonance spectroscopy analysis to determine the metabolic rates of N-acetyl-aspartic acid, choline and creatine in the lesion area and then compare them with those in the contralateral corresponding area; Magnetic resonance perfusion imaging was carried out to detect regional cerebral blood volume, regional cerebral blood flow, average pass time and peak time of the contrast medium; Fibertracking method was used to track corticospinal tract and the amount of connecting fibers between left Broca and Wernicke areas and then compare them with those in the contralateral corresponding area.MAIN OUTCOME MEASURES: Detection of the metabolic rates of Nacetyl-aspartic acid, choline and creatine in lesion area and the contralateral area; Detection of regional cerebral blood volume, regional cerebral blood flow, average pass time and peak time of the contrast medium in lesion area and the contralateral area; Comparison of the amount of connecting fibers between left cortioospinal tract and left Broca and Wernicke areas.RESULTS: ①The results of general magnetic resonance: there was atrophy in left temporal and frontal lobes, especially significant in temporal pole, which was manifested as widening of cerebral sulcuses and fissures,thinness of cortex, and enlargement of frontal and temporal angles. ② The results of functional magnetic resonance: N-acetyl-aspartic acid, choline and creatine in left temporal lobe and anterior part of frontal lobe decreased more obviously and regional cerebral blood volume and regional cerebral blood flow in these areas decreased,while average pass time and peak time of the contrast medium in these areas slightly increased as compared with those in the conitralateral areas; fraction of anisotropy values and the tracked fasciculus in left corticospinal tract decreased, and the connecting fibers between Broca and Wernicke areas also decreased as compared with those in the contralateral area.CONCLUSION: The lesion area of primary progressive aphasia is mainly located in left temporal and frontal lobes where low perfusion, low metabolic state and decrease of connecting fibers between Broca and Wernicke areas were shown as compared with those in the contralateral area, which might be the pathogenesis of this case of primary progressive aphasia.
7.Quantitative evaluation of vestibular function, balance function and optokinetic function in elderly person
Chinese Journal of Tissue Engineering Research 2005;9(23):231-233
BACKGROUND: Old people above 80 years old have a high incidence of dizziness and tumble, which are associated with weakening vestibular function, balance function and optokinetic function.OBJECTIVE:This study was designed to make a quantitative evaluation of vestibular function,balance function and optokinetic function in people over 80 years old.DESIGN:It was a quantitative study on posture function(vestibular and balance function),auditory function(frequency audiometry)and visual function (optokinetic function) in elderly persons.SETTING:Department of Otolaryngology ,General Hospital of Chinese PLA.PARTICIPANTS:Totally 41 old male inpatients with systemic diseases in Rehabilitation Department of the General Hospital of Chinese PLA, with an age from 80 to 94 were selected from March 1993 to January 1994.Of them,12 had tinnitus,20 had dizziness.During the same period,old cadres including 11 males and 7 females aged from 60 to 79 years with normal findings of physical examinations were selected as controls. No participant in this group suffered from tinnitus, deafness and dizziness. All the participants were voluntary.METHODS: Patients underwent full-scale otolaryngological examinations.Audiometry consisted of battery of tests including frequency audiometry and evoked auditory brainstem responses(ABR). Vestibular function (posture) was assessed by vestibular-ocular reflexes. Participants accelerated from 1 /s to 90 /s. Then, the angular speed was kept until the nystagmus disappeared,at the time a sudden stop was made.Changes in nystagmus during the tests were recorded.The eyes firstly turned to left and 10 minutes later turned to right.Slow-phase angular velocity was recorded and the imbalanced left/right rate was calculated.Vestibularspinal reflex (VSR) was measured using balance beam and the length of the sway of the center of gravity (CG) and the sway velocity of CG were all calculated. Balance tests using a cursor were employed to examine the central optokinetic system, including sweeping, tracking, and optokinetic responses.MAIN OUTCOME MEASURES: Frequency audiometry, vestibular-ocular reflexes, and vestibular-spinal reflex and optokinetic responses were examined to assess the posture function, auditory function and visual function in elderly persons over 80 years old.And the results were compared with those of balance function tests and visual function tests in old population aged from 60 to 79 years old.RESULTS:Practically,the number of old participants over 80 years old receiving the tests of frequency audiometry, vestibular-ocular reflexes, and vestibular-spinal reflex and optokinetic responses were 41,24,39,40 and 34 respectively;The number of 60-79 participants receiving balance tests and visual tests were 18 and 10.Individuals refusing to participate were omitted. ① Auditory function:In 41 elderly persons >80 years,13 ears (16%) had a normal middle frequency audiometry, 69 ears (84%) had a loss of hearing. ② Posture function: 15 (62%) had normal vestibular-ocular reflexes, and 9 (38%) had abnormalities in vestibular-ocular reflexes.Ten (26%) had a normal vestibular-spinal reflex and 29 (74%) had an abnormal vestibular-spinal reflex.③ Balance function:Of all the variables of balance function,the length of the sway of CG and the sway velocity of CG were most valuable. In populations in both brackets, the length of the sway of CG and the sway velocity of CG in eyes-closed condition were longer and faster than those in eyes-opened .condition (P < 0.01). In over 80 years group,the length of the sway of CG and the sway velocity of CG were longer and faster than in 60-79 group (P < 0.01). ④ Optokinetic responses:Optokinetic plus were not obviously different between over-80 group and 60-79 group (P > 0.05) and the latent period of sweeping and the distortion of tracking were significantly longer and greater in former group than in later(P < 0.05-0.01 ).CONCLUSION:Most of the elderly persons over 80 years have a decrease in auditory and posture functions.Their optokinetic and balance functions are degenerated more severely than 60-79 years old population.
8.Implemented observation on three-week rehabilitation intervention procedure in patients with acute myocardial infarction in cardiological department of municipal hospital
Chinese Journal of Tissue Engineering Research 2005;9(19):198-200
BACKGROUND: The rehabilitation treatment for acute myocardial infarction has started since 1980' s, but it has not been popularized yet in municipal hospitals due to limited conditions.OBJECTIVE: To probe into the possibility of 3-week rehabilitation intervention in patients with acute myocardial infarction implemented in municipal hospitals.DESIGN: Controlled retrospective analysis was designed.SETTING: Department of Cardiology of YingKou Center Hospital.PARTICIPANTS: Sixty cases of acute myocardial infarction were collected in Department of Cardiology of Center Hospital in Yingkou City in 1996 and they were taken as experimental group. Totally 58 cases of acute myocardial infarction hospitalized in 1986 were taken as the control. In experimental group, 44 cases were males and 16 cases females, aged varied from 34 to 79 years; of which, 45 cases were diagnosed as cardiac dysfunction and cardiac arrhythmia. The situation in the control was near basically to that in experimental group. During the intervention, in experimental group, 10 cases presented chest oppression, 3 cases were afraid to accept the intervention; but by monitoring and explanation, all of those accomplished the experiment.METHODS: In the control, only rational clinical management was given. In experimental group, at the same time of clinical management implemented,the rehabilitation treatment for 3 weeks was carried out for patients with acute myocardial infarction, aiming to earlier movement, earlier getting up, earlier discharge. The rehabilitation procedure stood by gradually increased exercise amount and individualization and it was adjusted according to age, situation of sickness and psychological state, etc. For instance, if the signs of over-endurance presented, the exercise would stop temporarily or the exercise intensity be reduced.MAIN OUTCOME MEASURES: Comparisons of exercise endurance, recovery time of exercise and hospitalizing time in 3 weeks of two groups.RESULTS: The patients in experimental group all accomplished 3-week rehabilitation intervention. In experimental group, the cases, in which, the exercise endurance was up to 5 to 6 equivalents 3 weeks after acute myocardial infarction, were more than the control (78%, 12%, P < 0.05). The cases that were able to go up-down stairs were more than the control(83%, 7%, P< 0.05) . The cases hospitalized < 3 weeks were more than the control (78%, 10%, P <0.05).CONCLUSION: It is practical and safe to carry on rehabilitation procedure for acute myocardial infarction in municipal hospital. Rehabilitation exercise at the early stage accelerates remarkably the recovery of acute myocardial infarction.
9.Determination of Boric Acid in Natural Mineral Water for Dinking by 1-(2-hydroxy-3-methoxybenzylidence-amino)-8-hydroxynaphalene-3-6-disulfonic Acid Spectrophotometry
Journal of Environment and Health 2001;18(3):172-173
The conditions of color-reaction of boric acid with 1-(2-hydroxy-3-methoxybenzylidence-amino)-8-hydroxynaphalene-3-6-disulfonic acid in buffer medium of ethamine at pH 6.5 were studied in the assy.The maximum absorption wavelength of this coordination compound was 420 nm.The coordination reaction showed a good linear relationship at the concentrations of boric acid of 0.4~0.6 mg/L.The detection limit and molar absorptivity (ε) was 0.08 mg/L and 4.6×104 L/(mol·cm) respectively.This method presented perfect selectivity under the existence of EDTA solution,had been successfully applied in the determination of boric acid in natural mineral water for drinking.
10.E-reading Room under the Concept of Open Information Services
Journal of Medical Informatics 2009;30(7):84-85
Using modem network and computer technology and characteristic digital resources, E - reading room has changed utiliza-tion modes of library information resources. The paper introduces the formation, current status and developing strategies of E - reading room open information service, and points out that this kind of service has become new model of library service in information era.