Objective To study the relationship between the expression of MAGE-10 genes and the clinical parameters of metastasis and recurrence of patients with Hepatocellular carainama (HCC). Methods The expression of MAGE-10 genes in tumor tissues,liver tissues adjacent to tumor and hepatocirrhosis tissues was examined by RT-PCR method.The relationship between positive expression rate of MAGE-10 genes and clinical parameters of metastasis and recurrence (such as AFP, AFU, Anti-HCV, HBsAg, AFPmRNA, diameter of tumor) in patients with HCC were studied. Results The positive expression rate of MAGE-10 genes significantly higher in tumor tissues than that in the surrounding tumor tissues (51 6% vs. 0%, ? 2=18 95,P 0 05).There was no expression of MAGE-10 in hepatocirrhosis tissues of 10 cases. Conclusions There was a high frequency of MAGE-10 genes expression in HCC,but it is unrelated to the tumor markers,metastasis and recurrence of HCC.

Acute ischemic stroke is a common disease serevely threatening the public health. The main management involves intravenous thrombolysis, intra-arterial thrombolysis and mechanical embolectomy. Recently, endovascular mechanical embolectomy is attracted more attention because it provides a good outcome for patients either ineligible not responsible for IV thrombolytic therapy. The article reviews the relative aspects with summerization in this field.

Objective To summarize the therapeutic efficacy of electrocoagulation for varicose veins of the lower extremities.Methods Totally 168 cases(238 limbs)of varicose veins of the lower extremities were treated with electrocoagulation in our department from April 2000 to April 2007.Through a small ankle incision,electrocoagulation probe was inserted ascendingly into the groin via the great saphenous vein.After high ligation of the great saphenous vein,the varicose veins and great saphenous trunk were electrocoagulated.Results The patients were discharged from hospital in one to two days after the operation.None of them had incisional infection.The ulcers at the ankle were healed in four weeks.Postoperative complications in this series,included Ⅰ degree burn injury in one limb,Ⅱ degree burn injury in one limb,superficial phlebitic pain in two limbs(two cases);and numbness around the ankle in 14 limbs(10 cases).Totally 148 cases with 208 limbs were followed up for 2 to 9 years with a mean of 6.6 years.During the period,the rate of recurrent varicosity was 3.4%(7/208);and healing rates of ache,dermatitis and eczema,ankle pigment,swelling around the calf and ankle were 95.3%(162/170),85.7%(12/14),41.7%(15/36)and 36.4%(16/44)respectively.Conclusion Electrocoagulation is a minimally invasive and effective method for the treatment of varicose veins of the lower extremities,with quick recovery and low rate of recurrence.

The analysis of 3 Teaching Basic Skills Contests showed that the Teaching Basic Skills contests could boost young teachers’teaching enthusiasm,urge them to improve their own quality,enhance their training on basic skills to improve their teaching abilities.

Objective To investigate the effects of low-dose ketamine combined with fentanyl or sulfentanyl in postoperative patient-controlled intravenous analgesia.Methods Two hundred cases with ASA Ⅰ~Ⅱ undergoing elective orthopedic operations were randomly allocated into four groups(50 cases for each group): 0.4?g/(kg?h) fentanyl(group F);0.2?g/(kg?h) fentanyl+120?g/(kg?h) ketamine(group FK);0.04?g/(kg?h) sulfentanyl(group S);and 0.02?g/(kg?h) sulfentanyl+120 ?g/(kg?h) ketamine(group SK).8mg of ondansetron was added to each recipe,and then diluted into 100ml with normal saline.The loading doses of all the patient-controlled-analgesics were 2ml administered 30min before the end of the operation.The background infusion doses were 2ml/h,while the pressing doses were 2ml,with intervals of 30min.Heart rate(HR),blood pressure(BP),respiration rate(RR),pulse O2 saturation and visual analogue scales(VAS),sedation score(SS) with adverse effects and the total times of pressing PCA pump button were observed and recorded in all patients respectively for 48h after operations.Results No statistically significant differences were found in HR,BP and RR among the four groups.VAS and the total pressing times in group F were higher than that in the other groups significantly(P

Objective To evaluate the influence of different combination of anesthetics on blood pressure (BP) and heart rate (HR) of aged patients with serious illness during operation. Methods Forty patients, aged 80～92, with physical status Ⅱ～Ⅲ as categorized according to American Society of Anesthesiologists (ASA) undergoing selective surgery, were randomly divided equally into two groups: in group A ancsthesia was induced with midazolam, fentanyl and maintained with isoflurane, and in group B anesthesia was induced and maintained with etomidate, sevoflurane and nitrous oxide. Mean arterial pressure (MAP), HR and bispectral index (BIS) were observed at the points of preinduction (T0), induction (T1), intubation (T2), incision (T3), 30 minutes after incision (T4) and extubation (T5). Results After induction, BIS decreased from 95?2 to 52?4, while MAP and HR decreased from 110?11mmHg and 73?8/min to 75?9mmHg and 59?4/min respectively, in group A. While in group B BIS decreased from 94?3 to 58?3, MAP and HR decreased from 103?8 mmHg and 76?6/min to 87?7 mmHg and 67?5/min, respectively. At the point of tracheal intubation, MAP and HR increased significantly in group A compared with group B (P

Objective To study the imaging manifestations of parietal coronary artery and the diagnostic value with 64-slice spiral CT.Methods 1000 patients with clinically suspected coronary heart disease underwent 64-slice spiral CT scan,the images were dealed with curved planar reconstruction and analysed at workstation.Results Parietal coronary arteriae were found in 380 patients,among them,314 cases were at the LAD,32 cases were at the CX,13 cases were at the RCA and multiple arteriae involved in 21cases.Conclusion 64-slice spiral CT coronary angiography is an effective methed in diagnosis of parietal coronary artery.

Objective To transform the vocabulary based Chinese personality (VBCP) to a sentence based Chinese personality inventory.Methods Based on the dimension theory and mapping sentence,347 sentences were developed and quantified with equal weight.772 subjects participated in a pilot study and an exploratory factor analysis was conducted to the collected data.A trial version of the Chinese Personality Inventory with 7 factors was developed.With the trial version as the survey instrument,3190 subjects from 22 provinces and centrally administered municipalities in China participated in the survey,the exploratory factor analysis,confirmatory factor analysis,annova,t-test,correlation and cronbach test were utilized in this research.The Chinese seven factors personality inventory (CSPI) was developed,which included seven factors with 130 items.Results The 7 factors of Chinese personality inventory were emotion,innovation,persistency,virtue,extraversion,agreeableness and tradition.42.27％ of the total variance of the seven factors was explained.The internal reliability coefficient was Cronbach' s α =0.902(P＜0.001),while the internal reliability coefficients among the factors were between 0.794-0.947.The retest reliability coefficients of the factors were between 0.696-0.921 (P＜ 0.001).Significant positive correlations (r ranged from 0.151 to 0.548,P＜0.01)were found between 5 of the 7 factors of CSPI,but innovation and tradition.Significant positive correlations (r ranged from 0.193 to 0.715,P＜0.05,P＜0.01)were found between the 7 factors and CSPI.Significant correlations between CSPI and EPQ-RSC were found (P＜0.05).Confirmatory factor analysis showed that thc inventory was valid,and NFI and CFI were greater than 0.90.Conclusion CSPI met the measurement requirement in validity,reliability and explanation ability.

Extensive in vitro studies reveal that multiple intracellular targets of Antrodia cinnomomea affect cell growth,apoptosis,angiogenesis,invasion and metastasis.These intracellular targets include tumor suppressor gene,cell cycle regulatory protein,transcription factor,angiogenic and metastatic factors,and apop-totic and survival regulators.In addition,Antrodia cinnomomea has immunomodulatory propertie,which plays an anti-cancer effect indirectly by means of enhancing immunity.

Objective To explore the significance of mediastinum drainage tube in prevention and treatment of intrathoracic anastomotic leak after esophagectomy. Methods The morbidity and prognosis of intrathoracic anas-tomotic leak after esophagectomy in 180 patients with esophageal or cardia carcinoma (group A) who used mediasti-num drainage tube in operation from 2006 to 2008 was studied retrospectively,and were compare with 154 patients (group B) without mediastinum drainage tube from 2004 to 2006. Results The morbidity of intrathoracic anasto-motic leak after esophagectomy was 1.67% (3/180) in group A,and 4.55% (7/154) in group B,but no difference between them(χ2=1.4807, P>0.05) were found. Compared to group B, the final diagnosis of anastomotic leak in group A was early [(6.7±0.6) vs (10.0±2.1) days after operation (t=2.62, P<0.05)] and the duration of fe-ver was short [(5.3±1.5)vs (43.0±20.9) hours (t=4.39, P<0.01)]. The prognosis of 3 cases in group A was well, who all recovered without operation and had shorten hospital days than group B [(23.7±5.9)d vs (45.3± 5.0)d,t=4.86,P<0.01)]. In 7 cases of group B,there were 5 cases underwent second operation,but only 3 cases recovered, the case fatality rate was 2.60% (4/154), higher than in group A (0, Fisher, P<0.05). Conclusions Although the mediastinum drainage tube used or not used in esophagectomy is unrelated with the occurrence of anas-tomotic leak, and the significance to use it is that it can help to discover anastomotic leak early, and control mediasti-num infection effectively without reoperation,and improve patients' prognosis.