1.Evaluation of Renal Function in Children with Hydronephrosis
Journal of Applied Clinical Pediatrics 1992;0(05):-
Hydronephrosis is one of the most common urological diseases in children.Most of hydronephrosis caused by ureteropelvic junction obstruction.Whether these children need operations were being argued.The current tendency is when the renal function become worse,operation is suggested needed,in order to save the renal function.So the methods how to evaluate the renal function are especially important,this article related to the current research and review.
2.The therapeutic effects of neuromuscular electric stimulation on patients with swallowing disorders after stroke
Zhao JIANG ; Yaping WANG ; Chengcheng GUO
Chinese Journal of Physical Medicine and Rehabilitation 2012;34(5):357-360
Objective To investigate the clinical therapeutic effects of neuromuscular electric stimulation (NMES) on patients with swallowing disorders after stroke. MethodsA total of 98 patients with a swallowing disorder after stroke were randomly divided into an NMES group (38 cases),a rehabilitation group (30 cases) and a control group (30 cases).In the control group the patients were treated with medication only; the in rehabilitation group they were treated with medication and swallowing rehabilitation training; in the NMES group they were treated with medication and NMES.The treatments lasted for 3 weeks in all groups.The swallowing function of patients in each group were observed and assessed with dysphagia scoring pre-and post-treatment.Complications of the swallowing disorders,side effects of treatment and the stomach tube leaving rate were observed. ResultsAfter treatment,the dysphagia scores of patients in the NMES and rehabilitation groups both increased,but the average scores in the NMES group were significantly higher than in the rehabilitation and control groups.The difference in therapeutic effect between the three groups was statistically significant.After treatment,the incidence of aspiration pneumonia in the NMES group was significantly lower than that in the control and rehabilitation groups.The average stomach tube leaving rate in the NMES group was significantly lower than that in the control group,but there was no significant difference in stomach tube leaving rates between the rehabilitation group and the NMES group.There was no significant difference among the three groups in malnutrition.No side effect was observed in any group.Conclusions NMES could alleviate post-stroke dysphagia and decrease the incidence of aspiration.The short-term therapeutic effect of NMES was better than that of swallowing rehabilitation training,but the long-term therapeutic effects were about the same in the two groups.
3.Changes of quantitative expression, adhering activity and genomic density polymorphism of complement type1 in erythrocytes (CR1) of patients with liver cancer
Haibin WANG ; Xinping ZHAO ; Feng GUO
Chinese Journal of Laboratory Medicine 2001;24(1):31-33
Objective To study the changes of quantitative expression,adhering activity and genomic density polymorphism of complement type 1 in erythrocytes (CR1) of patients with liver cancer (104 patients) and their clinical significance.Methods Polymerase chain reaction (PCR),HindIII restriction enzyme digestion,the quantitative assay of ECR1 and the adhering activity assay of CR1 in erythrocytes were used.Results No difference was observed between the patients with liver cancer (29.8%) and healthy individuals (25.3%) in the spot mutation rate of CR1 density gene (χ2 =0.537,P>0.05).The number and the adhering activity of CR1 in patients with liver cancer (0.83±0.22 and 47.1±6.5) were significantly lower than those in healthy individuals (1.26±0.33 and 62.4±7.6; t=10.5,P<0.0001).The number and the adhering activity of ECR1 in high expression genomic type (HH) liver cancer were obviously lower than those of healthy individuals,expecially those of the patients with advanced liver cancer.There was a good relationship between quantitative expression,adhering activity of ECR1 and liver cancer development.Conclusion Defective expression of CR1 in liver cancer is mostly acquired through central peripheral mechanisms.The changes of CR1 quantitative expression and adhering activity are consanguineously related to the severity and the activity of the development in patients with liver cancer.
4.Laparoscopic second-look exploration for ovary epithelial cancer: A clinical analysis of 14 cases
Yinghong WANG ; Xiaoqing GUO ; Xia ZHAO
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
Objective To investigate the feasibility,reliability,and complications of laparoscopic second-look exploration for ovary epithelial cancer.Methods The operation was performed under general anaesthesia.The 4-port laparoscopy was carried out.Physiological saline was used to wash the abdominal and pelvic cavity for cytological examination.Then the exploration of abdominal and pelvic cavity was performed,adhesions were dissected,and multiple punch biopsies(at more than 20 sites) were conducted in the abdominal and pelvic cavity.Results All the operations were completed successfully.The operative time was 61.3?16.7 min,and the hemorrhage volume was 98.7?32.1 ml.Positive findings were encountered in 4 cases(28.6%),3 of which(21.4%) were identified by the naked eye and 1 of which was identified by microscope,and negative findings,10 cases(71.4%).Of the 4 cases of positive findings,the tumor was located at the pelvic peritoneum or the paracolic sulci peritoneum.No abdominal organ injuries occurred,and no conversion to open surgery was needed.Delayed healing of umbilical incision happened in 1 case.Of the 10 cases of negative findings,recurrence of tumor was observed in 1 case(10.0%) at 48 months after operation.Conclusions Laparoscopic second-look exploration for ovary epithelial cancer is feasible,with advantages of minimal invasion,fast recovery,and good patient's tolerance.
5.A comparative study of treatment for necrosis of the femoral head by vascularized iliac bone flap combined with or without tantalum screw
Benjie WANG ; Dewei ZHAO ; Lin GUO
Chinese Journal of Microsurgery 2009;32(4):271-274,插1
-mid stage ONFH. It provided good blood supply and enough mechanical support as to reduce the progress of femoral head collapse.
6.Laparoscopic operations for malignant uterine tumors: Report of 62 cases
Yinghong WANG ; Xiaoqing GUO ; Xia ZHAO
Chinese Journal of Minimally Invasive Surgery 2005;0(07):-
Objective To investigate the feasibility of laparoscopic radical hysterectomy and abdominopelvic lymphadenectomy in the treatment of malignant uterine tumors.Methods Laparoscopic radical hysterectomy and abdominopelvic lymphadenectomy was performed in 62 cases of biopsy-confirmed early-stage malignant uterine tumors from February 2003 to August 2005.There were 26 cases of endometrial cancer and 36 cases of cervical cancer.Pelvic lymphadenectomy was conducted in all the cases;while selective lymphadenectomy of peripheral lymph nodes of the abdominal aorta was performed in 5 cases,followed by laparoscope-assisted vaginal hysterectomy(LAVH).Results The operation was completed under laparoscope in 61 cases,and a conversion to open surgery because of venous injuries was encountered in 1 case.The operation time was 165~265 min(mean,217 min);the intraoperative hemorrhage volume was 150~1200 ml(mean,260 ml);the number of excised lymph nodes was 13~23(mean,17).Bladder injury happened in 1 case and was successfully repaired under laparoscope.Postoperatively,urine retention developed in 4 cases and lymphatic cyst occurred in 5.Follow-up checkups for 1~28 months in 61 cases showed 1 case of recurrence at 3 postoperative month(stage Ⅱ_B cervical adeno-squamous carcinoma,withdrew from the treatment and died 4 months later).Conclusions Laparoscopic radical hysterectomy and abdominopelvic lymphadenectomy is safe,feasible,effective,and reliable.
7.A comparison between laparoscopic and open myomectomy
Yinghong WANG ; Xiaoqing GUO ; Xia ZHAO
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To investigate the clinical value of laparoscopic myomectomy.Methods A retrospective analysis was made on clinical data of 58 cases of laparoscopic myomectomy(Laparoscope Group) and 52 cases of open myomectomy(Open Group) from October 2002 to February 2004 in this hospital.Results The laparoscopic operation was all accomplished.The Laparoscope Group had significantly shorter operation time(58.0?11.2 min) than the Open Group(69.4?10.3 min)(t=(-5.535),(P=0.000)),less intraoperative blood loss(71.6?34.8 ml) than the Open Group(149.1?38.9 ml)(t=-11.029,P=0.000),lower postoperative pyrexia rate(21/58) than the Open Group(39/52)(?~2=16.642,P=0.000),shorter hospital stay(4.5?1.6 d) than the Open Group(7.6?2.1 d)(t=-8.760,P=0.000),higher total hospitalization costs (6 511.3?566.7 yuan) than the Open Group(6 286.8?387.5 yuan)(t=2.398,P=0.018),higher costs for anesthesia and operation(1 566.7?154.7 yuan) than the Open Group(946.6?156.6 yuan)(t=20.868,P=0.000),and lower costs for postoperative medication(703.5?140.2 yuan) than the Open Group(1 278.4?237.6 yuan)(t=-15.643,P=0.000).Follow-up observations in 56 cases in the Laparoscope Group and 50 cases in the Open Group for 18~34 months(mean,26 months) revealed no statistical differences in recurrence rate and pregnancy rate between the two groups.Conclusions Laparoscopic myomectomy has advantages of little hemorrhage,fast recovery,short hospital stay,and low complication rate,being one of ideal methods for the treatment of hysteromyoma.
8.The Effect of Liquiritin on Body Weight and Behavior of Depressive Rats
Zhiyu ZHAO ; Weixing WANG ; Hongzhu GUO
Chinese Mental Health Journal 2002;0(12):-
Objective:To observe the effect of liquiritin on body weight and behavior in depression model rats.Methods:Seventy-two male Sprague-Dawley(SD)rats were randomly assigned into normal control group,model group(stress+vehicle),fluoxetine group(stress+ fluoxetine)and three liquiritin groups(stress+liquiritin at different dose).The behavior of rats was detected by sucrose consumption test and forced swimming test.Results:The model rats showed significantly lower body weight(429?45/494?37,P
9.Influence of the number of balloon inflations during primary percutanoeus coronary intervention on myocardial perfusion and the extent of myocardial necrosis in patients with ST-segment elevation myocardial infarction
Guisong WANG ; Wei ZHAO ; Lijun GUO
Chinese Journal of Interventional Cardiology 1996;0(04):-
Objective To explore the relationship of the number of balloon inflations during primary percutanoeus coronary intervention(PCI) with myocardial perfusion and the extent of myocardial necrosis,and to identify the potential clinical efficacy of ischemic postcondioning in patients undergoing Primary PCI.Methods One hundred and fourty patients with ST-segment elevation myocardial infarction(STEMI) who underwent primary PCI were eligibly enrolled for retrospective analysis.The infarct-related artery(IRA) in all patients had to be either left anterior descending artery(LAD) or right coronary artery(RCA) with TIMI 0 flow grade and no collateral filling prior to intervention,and had to be completely reperfused with TIMI Ⅲ flow grade after PCI.Patients with cardiac arrest,cardiogenic shock,previous MI and pre-infarct angina were excluded.Patients were divided into two groups for analysis based on the number of balloon inflations performed during primary PCI:Group A included all patients in whom 1-2 inflations were applied,while patients in Group B received 3 or more inflations.Myocardial perfusion was evaluated by myocardial blush grade and ST-segment resolution.The extent of myocardial necrosis was evaluated by peak values of CK and CK-MB release and predischarge left ventricular ejection fraction(LVEF) measured by echocardiogram.Results The 2 groups showed similar baseline characteristics,while patients in Group B received more balloon inflations than those in Group A(4.7?0.9 vs.1.8?0.2,P0.05),but decreased to 1.65?0.49 mm and 0.98?0.37 mm(P
10.Effect analysis of adopting quantitative economic management of research quotas
Bin WANG ; Qiyong GUO ; Li ZHAO
Chinese Journal of Hospital Administration 1996;0(02):-
The publication of research papers is an important mark of achievements in scientific research. It is an index for checking the completion of various projects as well as a form of project completion. In order to better fulfill the tasks in scientific research, to enable more research projects to become bid winners, to turn out more quality papers, to produce outstanding results, and to further strengthen management and supervision of scientific research, the hospital the authors work with formulated at the end of 1999 "quantitative economic management of research quotas", which was put into effect at the beginning of 2000. An effect analysis of the implementation of the measure in the past three years showed that the desired results were basically achieved, academic advancement and personnel growth were greatly promoted, and the publication of research papers became a key index for evaluating the timely completion of research projects. In future the hospital plans to further improve the policy for rewarding writers of research papers and encourage quality academic papers to be published in key international journals.