Acupuncture Therapy ; Adult ; Alcoholism ; therapy ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged ; Peripheral Nervous System Diseases ; therapy

Animals ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Glomerulonephritis ; drug therapy ; pathology ; Humans ; Kidney Glomerulus ; pathology ; Phytotherapy ; Podocytes ; pathology

Objective Statistics the distribution regularity of algae literature in biomedical periodicals written in Chinese. Methods The specialized articles on algae are distributed in 285 types of Chinese periodicals with total 914 articles after retrieving Chinese Biomedical Literature Database(from 1995 to March of 2004). According to Bradford' law and Bradford zone method, three zones are divided into an approximately equal quantity of articles. The zone division is based on the quantity of articles in the periodicals and a digressive sequence as well. Results There are 14 periodicals in the first zone with 308 articles published, which are 4.91% of the total periodicals and 33.7% of the total articles. It could provide the 1/3 information and it is the Core Journals. Conclusion The articles published in Chinese Journal of Marine Drugs are the most, which reaches 90 and occupies 9.8% of the total; therefore, it shall be given priority when alga articles are selected. The scientific comments on periodicals can direct researchers on algae to attain necessary information.

Cartilage lesions resulting from acute or chronic injury are one of the major factors leading to joint disease and disability ,and eventually osteoarthritis. It is well known that articular cartilage in adults has a limited ability for self-repair,and represent a clinical management challenge. Numerous methods have been devised to augment its natural healing response. The most appropriate treatment option for an individual patient should be based on the pathologic characteristics of the lesion and the patient's symptoms, age and expectations. This review presents the current articular cartilage management and the direction in future therapeutic regimens.

Flavonoid Pilulae from Gegen were prepared by melting method. Using PEG 4000 and PEG 6000 as carrier. Serious of studies on the in yitro release kinetics were carried out.PEG4000 ; PEG6000 ratio had no effect on the release kinetics. PEG 4000: flavonoids ratio had an evident effect on the release properties of the pilulae, the higher the ratio,the faster the release rate. But when the PEG 4000, flavonoids ratio exceeded 10: 1, a reverse effect could be seen. Compared with "Gegen flavonoids" tablets, "Yufengingxin" tablets(release half time, T50= 94.79min), the pilulae gave a much fast release characteristic (T50 = 11. 56min).

Objective To study the effects of different factors influencing the quality of life of elderly esophageal cancer patients who returned to the community after surgery.Methods A total of 216 elderly esophageal cancer patients with complete clinical data who had returned to the community after surgery were followed up by questionnaires,including the European Organization for Research and Treatment of Cancer Quality of Life rating (EORTC QLQ-C30) and esophageal cancer supplementary (QLQ-OES18) scales.Results The overall quality of life score of the patients was (35.2±22.1),which was lower than that in the Norwegian norm data.Scores for cognitive function,constipation,diarrhea,shortness of breath and loss of appetite were similar to those in the norm data.Scores for physical function,emotional function,role function and were lower than those in the norm data,while scores for pain,fatigue,nausea and vomiting,sleeplessness and were higher than those in the norm data.The overall quality of life score was higher in male patients than in female patients (F =5.12,P=0.029),in patients with spouses than in those without spouses (F=5.61,P=0.016),and in patients without complications than in those with complications (F=5.48,P=0.002).The overall quality of life was higher with longer survival times after surgery (F=3.68,P=0.003).No significant difference in the overall quality of life score was found between different age-groups (F=4.23,P=0.212).Conclusions The overall postoperative life quality is poor in community elderly patients with esophageal carcinoma.Gender,marital status,postoperative survival time,and complications are among the factors influencing postoperative quality of life of community elderly patients with esophageal carcinoma.

Objective To observe the clinical effect of Xisui Huangu Formula combined with technetium [99Tc] methylenediphosphonate injection in the treatment of avascular necrosis of femoral head (ANFH). Methods A total of 73 patients were randomly divided into treatment group (37 cases) and control group (36 cases). The control group was given conventional western medicine treatment, while the treatment group was given Xisui Huangu Formula on the basis of conventional western medicine treatment. Clinical symptoms and joint function of the two groups were observed before and after treatment, and the clinical effects were compared. Results In the treatment group, 17 cases were cured, 17 cases improved, 3 cases were unrecovered, and the effective rate was 91.89%. In the control group, 4 cases were cured, 25 cases improved, 7 cases were unrecovered, and the effective rate was 80.56%. The difference was statistically significant between the two groups (P<0.05). Improvement of joint pain, lameness, dysfunction, and joint function in the treatment group were better than those in the control group (P<0.05). Conclusion Xisui Huangu Formula can significantly improve clinical symptoms of ANFH. Integrated traditional Chinese and Western medicine therapy is helpful to alleviate ANFH disease progression.

OBJECTIVE: To provide references for the improvement of drug safety of emergent public health events.METHODS: The characteristics of drug demands in emergent public health events were analyzed to guarantee the characteristics of drug safety so as to explore effective safeguard strategy.RESULTS & CONCLUSIONS: Special system and countermeasure are required to guarantee drug safety of emergent public health events.The strategy includes three aspects,i.e.adequate plan in advance,rapid response and timely consummation after the event.

Objective To study the association of sex, body mass index and insulin resistance with serum leptin in patients with type 2 diabetes. Methods one hundred and eight patients were divided into two groups according to BMI: diabetic obese group and diabetic normal BMI group.Their weight and height were measured. Fasting plasma glucose(FPG),fasting true insulin(FTI),postprandial true insulin(PTI),and fasting serum leptin(LEP) were also measured. ISI=1/(FPG?FTI) as insulin sensitivity index were used to analyse the relation between leptin and insulin resistance. Results ⑴The serum leptin,body mass index,FTI and PTI were significantly higher in diabetic obese group than diabetic normal BMI group. ISI was significantly lower in diabetic obese group than diabetic normal BMI group. ⑵Female serum leptin levels were significantly higher than male serum leptin levels in diabetic obese group and diabetic normal BMI group. ⑶Fasting leptin was correlated with sex. Leptin was positively corrected with body mass index,FTI and was negatively corrected with ISI. Serum leptin wasn't correlated with FPG. Conclusin Serum leptin level is associated with sex,BMI and insulin resistance in patients with type 2 diabetes.