Objective To investigate the curative effect and safety of posterior laminectomy in the treatment of intraspinal schwannoma .Methods 67 cases with intraspinal schwannoma were treated with posterior laminectomy surgery.The surgical conditions of 67 patients,such as surgery time,intraoperative blood loss and postoperative complications and tumor recurrence were observed and measured .The patients were followed up for 6 months,the preoperative and postoperative muscle strength , cervical spinal cord function improved were compared . Results 67 patients were successfully completed , the average operation time was ( 2.75 ±0.60 ) h, the mean intraoperative blood loss was(489.36 ±115.28)mL.There were postoperative 2 cases of exercise dysfunction after anesthesia awake , to be targeted after treatment symptoms were relieved;cerebrospinal fluid leakage in 4 cases, symptoms improved to be pillow supine , drainage and local pressure bandaged after treatment .All patients were followed up for 6 months,without recurrence of tumor .Compared with preoperation ,the postoperative muscle strength of 67 patients was significantly improved ,and restored to the level IV(61.19％) or level V(38.81％),the difference was statistically significant(Z=7.370,P<0.05).Compared with preoperation,the postoperative cervical spinal cord function score of 67 patients was higher [ ( 11 .72 ±0 .85 ) points ] , the difference was statistically significant ( t =29.341,P <0.05).Conclusion Posterior laminectomy surgery in the treatment of intraspinal schwannoma can significantly improve the patients'spinal cord function , effectively promote muscle recovery , the effect is more significant ,with high safety .