ObjectiveTo study the clinical features and pathogenesis of ophthalmoplegia in senile patients with diabetes, and access the possibility of its development.MethodsBesides routine ophthalmologic and ocular muscle examination, general and laboratory examinations were also done. Some patients were diagnosed also with the help of image processing.ResultsMonocular involvement happened in all 21 patients. 12 patients suffered from oculomotor nerve paralysis, 5 abducent nerve paralysis, 3 trochlearis nerve paralysis, and 1 compound nerve paralysis. Among these patients with complete oculomotor nerve panalysis, no papillary change appeared.Conclusions Microvascular pathologic change may be the pathogenetic basis of ophthalmoplegia for senile diabetic patients. Its prognosis is favorable if reasonable treatment is made.

Objective To study the curative effect of the laser photocoagulation combined with Xuefu Zhuyu decoction in treatment of patients with ocular fundus disease. Methods Ninety-seven patients with ocular fundus diseases were selected from the Department of Ophthalmology, The Central Hospital of Lishui City from June 2016 to June 2017. The patients were randomly divided into control group and observation group by the odevity of their sickbed number, including 48 odd numbers in control group and 49 even numbers in observation group. The patients in control group were treated with laser photocoagulation. The observation group added Xuefu Zhuyu Decoction in the foundation of control group. We compared the curative effects, side effects and vision improvements of each group. Results The total effective rate of the observation group was 95. 92％, which was significantly higher than the rate of the control group at 83. 33％. There was significant difference between the two groups(P＜0. 05). The vision improvements of the observation group after three and six months were better than those of the control group and the difference between the two groups was significant(P＜0. 05). The total numbers of occurrences of side effects in the control group and the observation group were 4 cases(8. 33％) and 5 cases(10. 20％) respectively, while the difference wasn't significant(P＞0. 05). Conclusion The laser photocoagulation combined with Xuefu Zhuyu decoction in treatment of patients with ocular fundus disease has better curative effect and less side effects, which helps visual recovery effectively, deserving clinical application and popularization.

Antimicrobial peptides (AMPs) are of great significance in the field of food, feed and medicine due to their wide spectrum of antimicrobial activity and new mechanism of action different from conventional antibiotics. AMPs production from natural sources is usually limited, and chemical synthesis is not economically practical, especially for the production of long peptides. Therefore, heterologous expression of AMPs has been widely studied as an alternative, and fusion expression plays an important role in increasing production. The present review mainly focuses on the types and bioactivities of AMPs. In addition, the recent strategies to the most commonly used carrier proteins for fusion expression of AMPs and prospects for future research were also discussed.
Anti-Infective Agents ; metabolism ; Antimicrobial Cationic Peptides ; biosynthesis ; genetics ; Escherichia coli ; genetics ; metabolism ; Glutathione Transferase ; biosynthesis ; genetics ; Green Fluorescent Proteins ; biosynthesis ; genetics ; Recombinant Fusion Proteins ; biosynthesis ; genetics ; Thioredoxins ; biosynthesis ; genetics