【Objective】To investigate the therapeutic effect of Shen Tao Ruangan Pill(STRP) for postoperative recurred liver cancer by a randomized and controlled trial.【Methods】Forty patients with postoperative recurred liver cancer were equally randomized into groups A and B.The two groups received routine symptomatic treatment,and group A was additionally treated with STRP(mainly composed of Herba Artemisiae Scopariae,Herba Hedyotis Diffusae,Herba Scutellariae Barbatae,Rhizoma Curcumae,Semen Persicae,Radix Angelicae Sinensis,Radix Salviae Miltiorrhizae,Radix Ginseng,Poria,Carapax et Plastrum Testudinis) and group B with Pingxiao Capsule.After 3-month treatment,the therapeutic effect was evaluated in the two groups.【Results】(1)After treatment,the symptoms were relieved in both of groups A and B,and group A had a better effect in relieving abdominal distention,anorexia and lassitude than group B(P0.05).(3) The non-progressive survival period was(172?11.64) days in group A and(143?10.95) days in group B;the survival rate within 3,6 and 10 months was 82.31%,70.42% and 50.33% in group A respectively,and 72.70%,65.70% and 46.33% in group B respectively;the median survival time was(203?20.87) days in group A and(167?19.58) days in group B,the difference being significant(P

Constipation is a common clinical symptom caused by different pathological and physiologi-cal factors.Because children are different age,the main reason for constipation is also different.The analysis should be carried out by different age groups.The cause and characteristic of constipation in different age child-hood are further explored and analyzed in the article in order to provide reference for diagnosis and to help treat-ment.

To build up total,perfect,scientific,feasible teaching quality monitoring system in sub-colleges,and further fully explore efficient monitoring method,technique is an important measure of ensuring teaching quality under the background of expansion of recruitment.This paper discusses total teaching quality monitoring system from guiding ideology,basic content,inplementing regulations of monitoring system.

Objective To know the environmental lead pollution status of rural areas around the mining area in Guangxi,2008.Methods From August to December,2008,the survey was carried out in 28 villages of 4 counties,which were located in basin of three rivers and their tributaries.Six lead-zinc-tin mines were situated in the investigated area.The local samples were collected,including 101 rice samples,30 paddy samples,59 vegetable samples and 45 samples of meat,viscera of poultry,5 fish samples,and 27 surface water samples,12 ground water samples,13 drinking water samples,29 cropland soil samples.The lead content of them were determined,the dietary survey on lead intake was performed among the residents living near the mining area also.Results 53.68%(102/190) of the crop samples revealed higher lead contents,which were over the standard limit,especially for rice(47.52%) and leafy vegetables(100%).The lead contents for five eggs samples,two peanuts samples and thirteen fresh corns were qualified.36%(102/190)of the samples of meat and viscera of poultry revealed higher lead contents,which were over the standard limit,especially for liver and chicken intestine.The lead intake only through rice and vegetables reached 4.55 mg in one week,which was over the tolerance dose by 0.52 times.Conclusion The lead intake of the residents living near the lead-zinc mining area are mainly from crop and vegetables and poultry.Environmental lead pollution is serious in the investigated area and must be controlled as possible as early.

Objective To evaluate the efficacy and safety of management of kidney calculi in non-uronephrosis by percutaneous nephrolithotripsy (PCNL) under ultrasound guidance. Methods From July 2005 to June 2008, 97 cases of kidney calculi in non-uronephrosis were performed by percutaneous nephrolithotripsy. A tube was first inserted into the pelvis through cystoscope, and saline was instilled to dilate collecting system. Antegrade percutaneous access was obtained under ultrasound guidance. A combination of pneumatic and ultrasonic lithotrite was used to disintegrate and remove stone under direct vision. Clinical data including operation time, complications and stone free rate were analyzed retrospectively. Results The perutaneous renal access was successfully established under ultrasound guidance in all patients, immediate phase Ⅰ lithotripsy was performed in 95 cases and delayed phase Ⅱ lithotripsy in 2 cases. Operation time was 70-180 min, average time was (96±23 ) min. The average blood loss was 60 ml (20-500 ml), 4 cases had transfusion during the PCNL and average 400 ml. Minor pyrexia ( < 39℃) was seen in 24 cases,whereas serious pyrexia was noted in 3 cases. Conservatively administered with appropriate antibiotics, the fever disapeared in 27 cases within 5 days postoperatively. Severe complications did not occur during nephrolithotripsy. Stones were cleared completely in 78 out of 97 cases (80.4%)during immediate phase Ⅰ lithotripsy, residual stone fragment was found in 19 cases. Conclusion The management of kidney calculi in non-uronephrosis by PCNL appears to be efficacious and safe under ultrasound guidance.

The effects of advanced glycation end products(AGE)on phosphorylation of ezrin/radixin/ moesin(ERM)protein in human umbilical vein endothelial ceils were detected by immunofluorescence cytochemistry and its mechanism was explored.AGE stimulated the phosphorylation of ERM protein in dose-and time-dependent manners(all P<0.05),which was involved in AGE receptor,Rho kinase,and p38 mitogen-activated protein kinase pathways.

[Objective] To explore the optimal pressure parameters for chyle plasma filtration under low-temperature conditions, and to improve the quality of chyle plasma treatment and filtration efficiency by improving experimental methods. [Methods] The filtration efficiency and filtration time of 30 severe chyle plasma samples under conventional preparation environment pressure and under preparation environment with a controlled filtration membrane pressure difference of 0.5 bar were compared. [Results] The absorbance of severe chyle plasma samples before and after filtration under two different preparation pressures was statistically significant (P<0.05), and both achieved the expected filtration effect. Under the preparation environment of controlling the pressure difference of the filtration membrane to 0.5 bar, the filtration was faster and with better effect, which was statistically significant compared to the conventional preparation environment pressure (P<0.05). [Conclusion] By selecting the optimal pressure parameters for filtering chyle plasma under low-temperature conditions, the efficiency of chyle plasma filtration under low-temperature conditions has been improved, and the practicality and reliability of low-temperature filtration technology have been enhanced.

BACKGROUNDHemifacial spasm (HFS) is a facial nerve disorder characterized by episodic involuntary ipsilateral facial muscle contraction. Information on Chinese patients with HFS has not been well-characterized. This study aimed to evaluate the clinical feature and the treatment status of HFS across China.

METHODSA cross-sectional study including 1003 primary HFS patients had been carried out in 15 movement disorder clinics in China in 2012. The investigated information was acquired from questionnaires and medical records including demographic data, site of onset, aggravating and relieving factors, treatments prior to the investigation, etc.

RESULTSIn this study, the ratio of male to female was 1.0:1.8, the mean age at onset was (46.6 ± 11.5) years. About 1.0% patients were bilaterally affected. The most often site of initial onset was the orbicularis oculi muscle. The most often affected sites were orbicularis oculi, zygomatic, and orbicularis oris muscles. Stress/anxiety and relaxation were most often aggravating and relieving factors, respectively; 2.3% patients had family history, 28.4% cases were combined with hypertension, and 1.4% patients were with trigeminal neuralgia. Botulinum toxin type A (BTX-A) injection was the most commonly used treatment, followed by acupuncture and oral medication. BTX-A maintained the highest repeat treatment ratio (68.7%), while 98.4% patients gave up acupuncture. The mean latency of BTX-A effect was (5.0 ± 4.7) days, the mean total duration of the effect was (19.5 ± 11.7) weeks, and 95.9% patients developed improvements no worse than moderate in both severity and function. The most common side effect was droopy mouth.

CONCLUSIONSThe onset age of HFS in China is earlier than that in western countries. The most often used two treatments are BTX-A injection and acupuncture, while the latter kept the poor repeat treatment ratio because of dissatisfactory therapeutic effect.

Adult ; Botulinum Toxins, Type A ; therapeutic use ; China ; Cross-Sectional Studies ; Female ; Hemifacial Spasm ; diagnosis ; drug therapy ; Humans ; Male ; Middle Aged ; Neuromuscular Agents ; therapeutic use