1.Imaging features of focal nodular hyperplasia-like lesions in the liver of patients undergoing antineoplastic chemotherapy
Liang YIN ; Jie GAN ; Zhangzhu LI ; Mingyan SHANG ; Zongchang LI
Journal of Practical Radiology 2024;40(3):390-393
Objective To investigate the imaging manifestations and pathogenesis of liver focal nodular hyperplasia-like(FNH-like)lesions in patients undergoing antineoplastic chemotherapy.Methods The clinical and imaging data of focal nodular hyperplasia(FNH)and FNH-like lesions patients confirmed by pathology after antineoplastic chemotherapy were analyzed retrospectively.Results A total of 67 FNH-like nodules were detected in 15 patients after antineoplastic chemotherapy,including multiple FNH nodules in 8 cases and sin-gle nodule in 7 cases.The mean detected time of FNH-like nodules was(18.9±11.7)months.Central scarring could be observed during follow-up in 5 nodules,and the rest showed atypical FNH features.Among 45 nodules examined with hepatocyte-specific con-trast medium,36 nodules showed slightly high signal in the hepatobiliary phase and other 9 nodules showed isosignal.Conclusion FNH-like lesions in patients during antineoplastic chemotherapy have certain imaging features,such as lack of central scarring,gener-ally smaller nodules,delayed enhancement,and hyperenhancement in hepatobiliary-specific phase,which are of significant value in the diagnosis and differential diagnosis of the disease.
2.Analysis on the imported measles cases in Beijing, 2014
Jiazi ZHANGZHU ; Li LU ; Rui MA ; Jiang WU ; Xinghuo PANG
Chinese Journal of Epidemiology 2015;36(6):617-619
Objective To analyze the imported measles cases who came to Beijing seeking for better medical services and to explore the feasible strategies for prevention and control of the situation.Methods Descriptive analysis was conducted for all the measles cases noted from the Measles Surveillance System,between January 1,2014 and December 31,2014.Results 3 328 measles cases were reported in Beijing,including 2 397 (2 397/3 328,72.0%) native residents and 931 (931/3 328,28.0%) came from other provinces.Peak of the imported cases appeared earlier than those native cases,with 934 cases (934/2 397,39.0%) having had hospital exposure 7-21 days prior to the onset of the disease.Majority of the imported were children,including 718 of them (718/931,77.1%) under the age of 15.Most cases were reported from 3 infectious disease hospitals (567/1 156 person-time,49.0%) and 2 children' s hospitals (445/1 156 person-time,38.5%).Original addresses of the imported cases distributed in 24 provinces,with 705 of them (705/931,75.7%) coming from Beijing' s neighboring province (Hebei).Clinic symptoms with epidemiological information were analyzed on 712 cases.704 cases (704/712,98.9%) presented rash at home town while another 621 cases(621/712,87.2%) developed rash 4 days after arriving in Beijing and were still in the infectious period.Conclusion There was a big amount of imported measles cases in Beijing that called for the elimination of the disease in a urgent phase.It is necessary to timely develop and conduct targeted prevention and control measures on the disease in Beijing.
3.Safety and epidemiological effects of the first China-made mass A (H1N1) influenza vaccination
Wen-Yan JI ; Li LU ; Min LV ; Liang MIAO ; Ting GAO ; Ruo-Gang HUANG ; Luo-Dan SUO ; Dong-Lei LIU ; Rui MA ; Rui YU ; Jia-Zi ZHANGZHU ; Wei-Xiang LIU ; Yang ZENG ; Xiao-Mei LI ; Jiang WU
Chinese Journal of Epidemiology 2010;31(5):481-484
Objective To evaluate the safety and epidemiological effects on the first mass vaccination program, using the China-made A (H1N1) influenza vaccine. Methods Descriptive epidemiology and cohort study design were used to assess the influenza A H1N1 vaccine on its safety and epidemiological effects. Results 95 244 subjects were immunized with A (H1N1) influenza vaccine. 193 adverse events were reported through AEFI Management System, with the Reported rates after immunization was carried out. Of 81 adverse reactions confirmed to be related to immunization,reported through the AEFI Management System. The epidemiological protection rate of A (H1N1)influenza vaccine showed a similar safety profile to seasonal flu vaccine. The vaccine demonstrated a good epidemiological effects against A (H1N1) influenza virus infection.