Objective To analyze the features of menopausal syndrome and its risk factors in patients from menopausal outpatient clinic,and further to evaluate menopausal syndrome and standardization managenent pathway of treatment.Methods The objects were enrolled in the menopausal outpatient clinic from Apr.2010 to May.2015,completing the self-designed questionnaires through one-by-one interview,including demographic information,and modified Kupperman Index.Results The average age of 907 menopausal women was 51.74+4.94 (aging from 30 to 70 years old).The incidence of (peri-)menopause syndrome was 95.7％,increasing with the prolonging of menopausal duration.The incidence and severity of surgery-related menopausal syndrome were higher than those of natural menopause.The five most frequent symptoms were:fatigue (84.6％) ＞ insomnia (77.3％) ＞ hot flashes sweating (76.3％) ＞ mood swings (72.3％) ＞ joint pains and heart palpitations (72.1％).Other factors such asage,menopausal status etc.also affected the menopausal symptoms.Conclusions Prevalence of (peri-) menopausal syndromes was high and it has many influencing factors.The incidence and severity of surgery-related menopausal syndrome are higher than those of natural menopause.