Objective To stuty the metabolites of marine fungus Julella avicenniae from the South China Sea.Methods The fungus J.avicenniae was extracted with AcOEt,separated,and purified by column chromatographies on silica gel.All the compounds were identified on the basis of spectral analysis(IR,MS,NMR) and chemical evidence.Results One novel compound was identified from its extract of marine fungus J.avicenniae from the South China Sea.Conclusion One novel compound,avicenniaene,is isolated from the marine fungus J.avicenniae from the South China Sea.