Objective To explore the effect of compound Tropicamide eye drop in pseudomyopia preventive treatment and summerize key points of nursing.Methods Sixty-six cases of juveniles with pseudomyopia were selected from patients in the Department of Ophthalmology, which were randomly divided into the experiment group(n=33)and control group(n=33). The control group used Atropine eye drop for treatment every night while the experiment group used compound Tropicamide. Both of Treatment durations were 30 days and the effects of the two groups after 10~30d were compared.Result The curative effect in the experiment group was significantly better than that of the control group(P<0.01)with statistically difference.Conclusions Effect of compound Tropicamide eye drop in treatment of juvenile pseudomyopia is better than that of Atropine eye drop. Recommendations and notes about the prevention and treatment of juvenile pseudomyopia should be provided for education.