2.Observation on therapeutic effect of warming needling on knee osteoarthritis
International Journal of Traditional Chinese Medicine 2010;32(3):243-244
Objective To explore an effective treatment for knee osteoarthritis.Methods All patients were randomly recruited into an observation group(n=41)and a control group(n=37).The observation group was treated by warming needling.while the control group was treated by common acupuncture combined with TDP. Results The effective rate of the observation group and the control group was 90.24%and 70.27%respectively,showing significant difference(P<0.05).Conclusion The warming needling was effective in treating knee osteoarthritis.
3.Diagnostic application of metabonomics in gastrointestinal cancer
Journal of International Oncology 2012;39(1):48-50
Metabonomics is a novel subject which develops after genomics,transcriptomics and proteomics.With its unique advantage,metabonomics has been used widely in screening diagnostic biomarker in a variety of tumors.At present,some diagnostic biomarkers are found in tissue,serum samples,urine samples and stool specimens of gastrointestinal cancer patients by metabonomics,which maybe helpful for the early diagnosis and individualized treatment of gastrointestinal cancer.
4.Discussion on teaching clinical pulmonary function in English for undergraduate medical students
Chinese Journal of Medical Education Research 2012;11(4):403-405
English-teaching among medical students is an important method to improve the teaching quality of foreign students and to train medical professionals capable of international communi cation.In the English-teaching among foreign and native undergraduate students,the course wares and teaching methods were designed after summarizing the features of students and teaching contents and were further improved during the practice.The continuing improvement of teachers′ English proficiency is also necessary to achieve good teaching quality.
5.Current status of chronic kidney disease in China and the challenge to laboratory medicine
Chinese Journal of Laboratory Medicine 2012;35(9):769-772
Chronic kidney disease (CKD) has become a public health issue worldwide.A recent cross-sectional survey revealed that the prevalence of CKD in residents aged 18 years or older was 10.8%,indicating the challenge of CKD in China.The major indicators of kidney damage include estimated glomerular filtration rate (eGFR),proteinuria and hematuria.It is recommended that laboratory should report eGFR when reporting results of blood creatinine.Both of Chinese equation and Chronic Kidney Disease Epidemiology Collaboration equation could be used.The process of creatinine measurement should be standardized.For evaluation of proteinuria,urinary creatinine should also be measured when using spot urine sample.Considering the high false positive rate and low false negative rate of urine routine test for hematuria,it is recommended that microscopic examination on urinary sediment should be done for those with positive hematuria by urine routine test.(Chin J Lab Med,2012,35:769-772)
6.Wait and see in rectal cancer after neoadjuvant chemoradiotherapy
Journal of International Oncology 2011;38(8):620-623
Neoadjuvant chemoradiotherapy has been used as a standard treatment for patients with locally advanced (T2 and T3 ) rectal carcinoma. Some patients who receive neoadjuvant chemoradiotherapy obtain pathological complete remission, namely, the absence of any tumor cells in the surgical specimens. The patients who obtain pathological complete remission get a better survival rate after canceling operation. Researches are still needed to investigate whether it is safe for patients in order to avoid risk and adverse reaction.
7.Exploration of the method to medical humanistic education
Chinese Journal of Medical Education Research 2011;10(9):1064-1066
Medical humanistic education becomes “remarkable leaning” because many problems arise from the development of contemporary medicine such as the meaning of life,the medical aim,the medical model and doctor-patient relationship etc.Multi-channel and multi-modal development of medical humanistic education has become a must to understand medicine and makes it develope soundly,and all-directional resultant force and the environment of medical humanistic education,striving for studies,is an exploration and even a mission and responsibility
8.Phospholipase A2 and Cancer
Journal of International Oncology 2011;38(12):897-900
Phospholipase A2 (PLA2) is consisted of a large group of enzymes,which can hydrolyze Sn-2 ester bond of the phospholipids and have different structures and functions.According to the latest related researches,many subtypes of PLA2 express abnormally in a various of tumors and have a close relationship with cancer proliferation,apoptosis,invasion,metastasis and prognosis.Different subtypes have different effects on neoplasms.PLA2 can supply a new insight on cancer therapy.
9.Mineralization reaction during osteogenic differentiation of myoblasts stimulated by bone morphogenetic protein 2***☆
Chinese Journal of Tissue Engineering Research 2012;16(20):3620-3625
BACKGROUND: In recent years, it has been confirmed by a variety of ways that myoblasts can differentiate into osteoblasts under the induction of recombinant human bone morphogenetic protein 2 (rhBMP-2).OBJECTIVE: To explore the mineralization reaction during the osteogenic differentiation of myoblasts under the induction of recombinant rhBMP-2 and the feasibility of osteogenic phenotype expression by in vitro induction. METHODS: Myoblasts were isolated and harvested from neonatal Wistar rats using differential velocity adherent technique and trypsinization method. After in vitro culture, purification and identification, myoblasts at passage 3 were induced by a medium containing rhBMP-2 for 21 days. Myoblasts in the control group were cultured in vitro in complete medium without rhBMP-2 for 21 days. RESULTS AND CONCLUSION: After rhBMP-2 induction, myoblast proliferation gradually slowed down. A small quantity of opaque secretory granules were found in the cytoplasm on day 8 after induction; the number of opaque secretory granules increased on day 14 after induction; and a great quantity of opaque secretory granules were found in the cytoplasm on day 21 after induction while the myoblasts without induction fused into contractile myotubes. The alkaline phosphatase activity of the induced myoblasts increased as time extended; myoblasts reacted positively in the alkaline phosphatase staining, immunochemical staining for type Ⅰ collagen and calcium node staining on day 21 after induction. These findings suggest that mineralization reaction is found in rat myoblasts by rhBMP-2 induction and myoblasts can differentiate into osteoblasts under certain inducing conditions in vitro.
10.Hemodynamic monitoring, fluid volume and cardiovascular function assessment in septic shock
Chinese Pediatric Emergency Medicine 2012;19(5):452-455
Hemodynamics is monitoring a series of physiological and pathological parameter changes such as blood flow,the chamber pressure of the heart,pressure or resistance of cardiovascular and cardiopulmonary system.Traditional hemodynamic monitoring in septic shock manily includes central venous pressure,cardiac index,blood lactate and pH.In recent years,expanded non-invasive or invasive monitoring technologies include central venous or mixed venous oxygen saturation,continuous ultrasound associated with underlying cardiac output monitoring and pulse indicator continuous cardiac output.Macro-hemodynamic,metabolic and microcirculatory parameters constitute a new hemodynamics network.In order to properly assess the patient's blood volume and circulation function and to overcome the limitations of a single parameter,it is need to emphasize analysis and integration of the various parameters.