1.Wireless human body communication technology.
Journal of Biomedical Engineering 2014;31(6):1389-1393
The Wireless Body Area Network (WBAN) is a key part of the wearable monitoring technologies, which has many communication technologies to choose from, like Bluetooth, ZigBee, Ultra Wideband, and Wireless Human Body Communication (WHBC). As for the WHBC developed in recent years, it is worthy to be further studied. The WHBC has a strong momentum of growth and a natural advantage in the formation of WBAN. In this paper, we first briefly describe the technical background of WHBC, then introduce theoretical model of human-channel communication and digital transmission machine based on human channel. And finally we analyze various of the interference of the WHBC and show the AFH (Adaptive Frequency Hopping) technology which can effectively deal with the interference.
Computer Communication Networks
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Humans
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Models, Theoretical
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Wireless Technology
2.Test methods of visual alarm signal for medical alarm systems.
Chinese Journal of Medical Instrumentation 2014;38(3):219-221
This paper introduces several test methods of characteristics of alarm indicator lights which can be used in the medical alarm system to verify the compliance of YY 0709-2009. These methods include the direct measurement of the pulse current supply of the alarm signals, image analysing of a video and reception by photoelectric sensor. After the comparation of the advantages and disadvantages among these methods, this paper proposes a new method of signal reception. This method which used a silicon photocell as the sensor with light filter in its front, and amplified circuit in the output end then used an oscillograph as the reviewer, has resolved the testing difficulties of the flashing signal simulating by LCD, and can be applied to test the alarm indicator lights in any medical electrical equipment.
Clinical Alarms
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Equipment Design
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Signal Processing, Computer-Assisted
3.Clinical study on Treatment of Active Ankylosing spondylitis with Total panax Notoginseng Saponins
International Journal of Traditional Chinese Medicine 2009;31(4):305-306
Objective To evaluate the effectiveness and safety of treating active ankylosing spondylitis with total panax notoginseng saponins (PNS). Methods sixty-two patients were randomly recruited into a control group and a treatment group, with thirty-one patients in each group. All patients were treated with the routine therapy of NSAIDs and DMARDs. The treatment group was given PNS additionally, with 400mg PNS joined with 200ml normal saline being intravenously dripped daily. The therapeutic course was 14 days for both groups. The observation items for evaluation included symptoms, signs, and side effects. Results Compared with previous state before treatment, the lumbosacral portion pain and the count of joint pain was reduce, the time of morning stiffness was shortening, erythrocyte sedimentation rate (ESR), and C-reaction protein (CRP) were all significantly reduced (P<0.05) ; There were significant differences in the total effectiveness rates between the two groups (P<0.05) ; while no notable difference was found in adverse drug reaction between the groups (P>0.05). Conclusion It is effective that treating active ankylosing spondylitis with PNS plus NSAIDs.
4.Evaluation and clinical application of the subaxial cervical spine injury classification system
Tiansheng SUN ; Zhicheng ZHANG
Chinese Journal of Trauma 2009;25(5):403-407
Objective To evaluate the interobserver reliability and intraobserver reproducibility of the subaxial cervical spine injury classification system (SLIC) and identify its guidance on clinical treatment of spinal cord injuries. Methods Thirty consecutive patients with subaxial cervical injury ad-mitted into our hospital between December 2007 and July 2008 were enrolled in this study and underwent neurological examinations followed by X-ray, CT, and MRI examinations. SLIC was evaluated in aspects of fracture morphology, disco-ligamentous complex (DLC) status and ncurologic status. According to the morphology in image, the fractures were classified into normal, compression, burst, distraction and trans-lation/rotation. According to injury severity, DLC was sorted into intact, indeterminate and disrupted types. Neurologic status was classified into intact, nerve root injury, complete/incomplete spinal cord in-jury and continuous spinal cord compression. The clinical and radiographic data of 30 patients with subax-ial cervical injury were evaluated prospectively by four groups of surgeons to count SLIC scores and decide treatment based on SLIC scores. The evaluation was done again three months later. Cohen' s unweighted kappa coefficients were calculated for the key parameters of each classification system ( morphology, neurologic status, DLCstatus, total score, and proposed management) to analyze the reliability and repreducibility of SLIC. Based on SLIC, the treatment method was selected and the neurological function recovery and the complications observed. Results The interrater Kappa statistics of all subgroups ( morphology, DLCstatus, total score, proposed management) were within the range of moderate to substantial reliability (0.47-0.69). Kappa coefficient was 0.83 for neurologic status, with high reliability. There was no statistical difference upon Kappa values in two evaluations. The interrater Kappa statistics of all sub-groups ( morphology, DLCstatus, total score, proposed management) were within the range of moderate to substantial reproducibility (0.53-0.78). Kappa coefficient was 0.89 for neurologic stares, with high repreducibility. The recovery rate of neuroiogie function was 79.2%. There was no aggravation of neurological status, with low incidence of complications. Conclusions SLIC has advantages of high reliability and reproducibility, simple use, exact evaluation and can facilitate decision-making in treatment of subaxial cervical spine injures.
5.Superficial siderosis of the center nervous system
International Journal of Cerebrovascular Diseases 2009;17(4):309-311
Superficial siderosis of the central nervous system is a seldom disease in clinical practice. Its most common clinical manifestations are hearing loss and ataxia. It is a hemosiderin deposition in the surface of the brain and spinal cord after chronic subarachnoid hemorrhage. Magnetic resonance imaging can make the diagnosis. However, further research and clinical verification are needed.
6.Influence of early rehabilitative exercise in patients with myocardial infarction
Chinese Journal of Tissue Engineering Research 2006;10(24):164-166
BACKGROUND: In treatment of traditional acute myocardial infarction,patients were required to lie on the bed resting for 1-4 weeks. Recently research showed that early rehabilitation exercise in myocardial infarction patients could ameliorate the reservation of cardio function, increase exercise tolerance, augment myocardial hemoperfusion, decrease myocardial ischemia and reduce the anxious and depressive emotion.OBJECTIVE: To observe the influence of early rehabilitation movement on activity of daily living, duration of hospital stay, mean hospitalized cost,incidence rate of arrhythmia and recurrence rate of myocardial infarction in two years.DESIGN: Non-randomized concurrent control analysis.SETTING: Beijing Tiantan Hospital.PARTICIPANTS: Totally 80 patients with acute myocardial infarction,who were hospitalized at Department of Circulation, Beijing Tiantan Hospital from August 2002 to October 2003, were enrolled. They were all at most 70 years old with stable pathogenetic condition. Left ventricular ejection fraction (LVEF) was over 35%. They were not combined with severe hypertension, severe pulmonary disease, nerve and disease of locomotor system.METHODS: The selected cases based on patients' will were assigned into two groups (n=40), ①early rehabilitation group: They were treated with routine drugs, absolute bed rest for 24 hours. At day 2 the head stock was rose about 30°to do passive exercise of extremity joint. At days 3-5, the patients sat on the bed, 3 times per day. At days 6-7,the patients stood at bedside, 3 times per day. At days 8-9, the patients moved joints of extremities at bedside and walked slowly in room. At days 10-14, the patients exercised walking. If there were angina pectoris attacks, serious cardiac arrhythmias or dyspneic respiration, etc., the movement should be suspended or the exercise intensity came back to that in the former stage. ②Absolute bed rest group: The patients were absolute bed rest, and only treated with routine drug without any rehabilitation training.MAIN OUTCOME MEASURES: Barthel index (full mark was 100 points, and < 60 points represented unable self-care) was used to assess activity of daily living of patients. Mean duration of hospital stay, mean hospitalized cost, incidence rate of arrhythmia and recurrence rate of my ocardial infarction in two years were compared between the two groups.RESULTS: A total of 80 patients that conducted the therapy and follow up were involved in the result analysis. ①Mean duration of hospital stay and mean hospitalized cost in the early rehabilitation group were less than those in the absolute bed rest group (17.1 days vs 24.5 days; 9 021.23 yuan vs 12 383.45 yuan; P < 0.05). ②Barthel index: There was insignificant difference before treatment between the two groups. It was significantly higher in the early rehabilitation group than that in the absolute bed rest group before discharge (81.43±13.57,70.68±11.48,P < 0.05). ③Six and seven patients had the onset of arrhythmia in the early rehabilitation group and the absolute bed rest group, respectively. ④Follow-up observation was performed for two years. The recurrence rate of myocardial infarction in the early rehabilitation group (5% ,2/40) was obviously lower than that in the absolute bed rest group (22 %,9/40).CONCLUSION: The early rehabilitation training is of benefit to elevate activity of daily living of myocardial infarction patients, reduce mean duration of hospital stay and mean hospitalized cost and decrease recurrence rate.
7.Relationship between the advanced glycation end products content and expressions of RAGE,ICAM-1 in vascular tissue of diabetic rats
Basic & Clinical Medicine 2001;21(2):131-135
In this study,the relationship between the advanced glycation end products(AGEs) and the expressions of receptor for AGEs(RAGE),intercellular cell adhesion molecule-1(ICAM-1) was investigated.The diabetic rat model was reconstructed and the fluorescence method,RT-PCR and in-situ hybridization techniques were used to detect AGEs content and the expressions of RAGE and ICAM-1 gene in the aorta and cardiac tissues.The results showed that AGEs content in aortic and cardiac tissues increased(P<0.01) in diabetic rats; The expressions of RAGE and ICAM-1 enhanced (P<0.05~0.01) and were positively correlated with the quantity of AGEs accumulation(P<0.01) in the aorta and cardiac tissue.These parameters change in the diabetic rats can be improved with aminoglumine(AG) treatment.Suggesting that AGEs might induce RAGE and ICAM-1 expression.It's postulated that AGEs binding to RAGE play an important role to result in diabetic endothelial cells dysfunction and lesion.
8.Toll-like receptor 4 signalling pathway in microglia and central nervous system injury
International Journal of Cerebrovascular Diseases 2011;19(12):944-947
The mechanism of central nervous system injury is complex.Microglia cells participate in a variety of central nervous system diseases and damage processes.Toll-like receptor 4 (TLR4) mediates the microglial activation and the expression of inflammatory cytokines.It is one of the important receptor proteins for microglia cells performing their functions.This article briefly introduces the role of TLR4 signal pathway in the central nervous system injury.
9.Modified sliding myofascial flap of the rectus abdominus muscles for the closure of huge planned abdominal hernia
Chinese Journal of Digestive Surgery 2013;(7):524-526
Abdominal increment is applied to patients with abdominal compartment syndrome (ACS) after severe trauma,while for some patients,intra-abdominal volume increment could not close the fascia within the primary stage.For theses patients,abdominal wound skin grafting was conducted,and the planned hernia was formed.Planned abdominal hernia developed over time,and finally huge incisional hernia was formed.This article described a modified sliding myofascial flap of the rectus abdominus muscles for definitive abdominal wall reconstruction for a patient with huge planned abdominal hernia,and a good curative effect was obtained.
10.Progress of research On genetic markers of Oncomelania hupensis
Chinese Journal of Schistosomiasis Control 2010;22(1):90-95
With the progress of the genetics and the molecular biology and biotechnology,the development of genetic markers of Oncomelania hupensis also has gone through the course from indirect methods to direct methods and from sketchy results to precise results.The paper reviews the progress of research on genetic markers of O.hupensis.