1.Thinking about improving the cross-cultural communication capacity of the teaching foreign language on Chinese medicine
Chinese Journal of Medical Education Research 2011;10(9):1047-1049
The purpose of foreign language teaching in Chinese medicine is not only translation,but also clearly the role and the purposes of translation.Inputing a culture to another culture is not culture exchange,but cultural coagulation.Expressions with modem scientific system allow speculative natural philosophy freed from the ancient Chinese-style paper into the theory expressed by modem scientific language in order to solve the problems of teaching foreign languages of traditional Chinese medicine texts.
2.Oncogenes related to thyroid cancer
Journal of International Oncology 2013;(1):8-11
Research of oncogenes related to thyroid cancer has an important significance to reveal pathogenesis and identify benign and malignant lesions.At the mean time,these genes are helpful to find the reliable and feasible detection means of early diagnosis for thyroid cancer.
3.Improvement of mouse spermatogonial cells transplantation method
Acta Anatomica Sinica 2010;41(1):165-168
Objective To improve the current method of spermatogonial cells transplantation, and make the new method become more operative and easy to carry out. Methods The spermatogonial cells in rC57BL6/tg14 (act-EGFO-Osb Y01) mice that expresse GFP protein were collected as the donor cells, and by using a modified syringe, and then were injected into the seminiferous tubules of pretreated wild type GFP-null mice through testicular efferent duct. The transplantation outcome was evaluated by trypan blue stainting and fluorescent microscopic examination and pathohistological analysis of transplanted testis. Results The transplanted testis of recipient mice showed green fluorescence signal, and the signal of seminiferous tubules was found significantly higher than that of the surrounding tissues. The transplanted GFP-positive cells generated colonies and spermatogenesis but pretreated wild type GFP-null mice were not found. Conclusion The expressed GFP protein spermatogonial cells in rC57BL6/tg14 mice were successfully transplanted in the wild type GFP-null recipient mice, fourthermore the improved transplantation method simplified the triditional one and achieved the same transplantation results.
4.The Pharmacodynamic Action of Zidian Prescription on ITP
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Qbjective]To observe the effects of Zidian prescription extracted by two kinds of process on ITP mice.[Methods] Using APS to inject into mice to induce the ITP model.Mice were divided into 6 groups: C,M,DC,X,S and G groups.The number of platelet on 7th day and 14th day were measured in mice.Meanwhile the weight on 7th day and 14th day and the degree of subcutaneous bleeding were recorded.[Results]There is no significant difference in weight and the number of platelet in all groups before the experiment.Compared with the C group,the weight is in down trend in M group on 7th day,the weight and the number of platelet were declined in M group on 14th day,the petechia was more clearly in M group.Compared with the M group,the weight is up trend in DC,X,S and G groups on 7th day,the weight and the number of platelet are enhanced in DC,X,S and G groups on 14th day,the petechia was decreased in DC,S and G groups significantly.Compared with the DC group,the number of platelet is decreased in X,S and G groups.Compared with the X group,the number of platelet is increased in S and G groups.[Conclusion] Zidian prescription extracted by two kinds of extraction process has an remedial effect on ITP mouse.There is no significant difference between the two kinds of extraction process.
6.Function of fetal microchimerism during disease and tissue repair in parous women
Chinese Journal of Tissue Engineering Research 2012;16(6):1133-1136
BACKGROUND: Fetal microchimerism is a kind of stem cells which comes from fetus in pluripara. The research on fetal microchimerism is a hotspot because it may affect the health condition of pluripara.OBJECTIVE: To introduce the methods of how to detect fetal microchimerism, and the function of fetal microchimerism during disease and tissue repair of the mother.METHODS: Fetal microchimerism was used as a key word, and papers published before 2011-05-20 were retrieved in PubMed. Repetitive papers were eliminated.RESULTS AND CONCLUSION: Totally 655 papers were retrieved, and finally 26 were reviewed. There are several methods used for fetal microchimerism detecting, and fetal microchimerism may pay an important role in the pathomechanism of pluripara autoimmune diseases, cancer and tissue repair.
7.Magnetic resonance imaging of vulnerable carotid plaques:plaque features and risk prediction
International Journal of Cerebrovascular Diseases 2014;22(2):144-149
Carotid artery atherosclerosis is a treatable and preventable cause of ischemic stroke.Increasing studies suggest that carotid plaque characteristics may be a superior means for predicting ipsilateral cerebrovascular events as compared with the degree of carotid artery stenosis.The major MRI features of vulnerable carotid plaques include large lipid-rich necrotic cores,intraplaque hemorrhage,plaque rupture,and calcification.This article reviews the major MRI features of vulnerable carotid plaques and their roles in predicting ipsilateral cerebrovascular events.
8.Meta analysis of BISAP score system in predicting the severity of acute pancreatitis
Chinese Journal of Pancreatology 2014;14(3):149-153
Objective To investigate the value of BISAP scoring system in predicting the severity of acute pancreatitis.Methods Medline,EMBASE,Science Direct,Springer link,CBM,Cnki,Wan fang and VIP database were retrieved by computer between January 2000 and March 2013,and articles of BISAP score system in predicting the acute pancreatitis were collected according to strict inclusion criteria.Quality assessment was made by QUADAS scale.Meta-Disc1.4 software was used to analyze the heterogeneity of included articles and perform quantitative synthesis,as well as calculate the pooled sensitivity and specificity,positive likelihood ratio,negative likelihood ratio,and draw the ROC curve,and the results were presented with 95% CI.Results A total of 11 articles were included,and there were 7 Chinese articles and 4 English articles.According to QUADAS scale,there were 4 articles of A grade,5 articles of B grade,2 articles of C grade.There were 6 studies using 2 as BISAP cut-off value,and 9 articles using 3 as cut-off value,while 4 studies using 2 cut-off values.Pooled analysis showed diagnostic odds ratio of 8.03 (95 % CI 5.66-11.38) when cut-off value was 2,and diagnostic odds ratio of 7.49 (95% CI 5.35-10.49) when cut-off value was 3.There were moderate heterogeneity in both groups (I2 =63.3 %,P =0.018; I2 =56.1%,P =0.019).When BISAP cut-off value was 2,the pooled analysis of sensitivity,specificity,positive likelihood ratio,negative likelihood ratio and area under curve (AUC) were 59% (95% CI56%-63%),82% (95% CI 80%-83%),3.50 (95% CI2.96-4.14),0.45 (95% CI0.36-0.56) and0.82; and when BISAP cut-off value was 3,the corresponding values were 44% (95% CI41%-47%),90% (95% CI 89%-91%),4.59 (95% CI 3.31-6.37),0.64 (95% CI 0.61-0.68) and 0.64.The former had a high sensitivity,low specificity and large AUC,while the latter had a low sensitivity,high specificity and small AUC.Conclusions The best cut-off value of BISAP in predicting SAP is 2.When cut-off value is 2,the misdiagnosis rate is low,and the false positive rate is in the acceptable range,which is suitable for clinical application.
9.Effect of leucosonurn combined psychological intervention on workers exposing benzene
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):276-277,279
Objective To explore the effect of combined use of schizophrenia combined with psychological intervention on benzene exposure to workers. Methods A total of 106 workers were randomly divided into observation group and control group. The 106 workers were randomly divided into observation group and control group. The workers were randomly divided into observation group and control group. 53 patients were given the observation group combined with the psychological intervention, given the control group placebo, 3 months after the intervention to compare the two groups of workers blood parameters, oxidation-antioxidant indicators and genetic damage indicators. Results The WBC and PLT were significantly increased after treatment (P<0.05 or P<0.01), while MDA and MN were significantly decreased (P<0.05). Conclusion Leucosonurn has some protective effects on blood system damage, oxidative damage and cytogenetic damage caused by exposure to benzene, and the combination of psychological intervention is beneficial to the early prevention of benzene poisoning.
10.Influence of iron metabolism disorders on glucose metabolism and HbA1c
Chinese Journal of Diabetes 2017;25(8):765-767
HbA1c has already been one of the standard diagnostic criteria for diabetes and pre-diabetes.However,disorders of iron metabolism could affect glucose metabolism through various pathways,and influence HbA1c level directly or indirectly.So under certain circumstances,it may affect the diagnosis of glucose metabolic status.Here we reviewed researches about the interference of iron metabolism disorders on HbA1c.