1.Comparison of frontoparietal drill versus parietal drill in burring hole and drainage for chronic subdural hematoma
Chengjun LUO ; Honggang WU ; Ao ZHAN ; Shan WANG ; Tinggang WANG
Journal of Regional Anatomy and Operative Surgery 2017;26(9):679-681
Objective To investigate the efficacy of frontoparietal drill versus parietal drill in the burring hole and drainage for chronic subdural hematoma(CSDH),and provide an evidence for clinical application.Methods A total of 82 patients with CSDH from January 2013 to January 2016 in our hospital were randomly divided into observation group and control group.The observation group chose frontoparietal drill which located at the front 1/4 point at the axial view with the thickest hematoma.Control group chose parietal drill which nearby the parietal tuberodties at the axial view with the thickest hematoma.The postoperative residual hematoma volume,intracranial gas volume,recurrence rate,neurologic function and mental state between two groups were compared.Results The postoperative residual hematoma volume,intracranial gas volume,the recurrence rate and CSS were lower compared with the control group,the differences were significant(P<0.05).The MMSE score of observation group were higher that of the control group,the difference was significant(P<0.05).Conclusion The frontoparietal drill has a better effect to remove the hematoma and promotes neural functional recovery.
2.Clinical effects of atorvastatin in patients with acute ischemic stroke
Hong-Xia ZHOU ; Xing-Yuan WANG ; Li-Juan FAN ; Shan-Jin YANG ; Hong-Bing CAO ; Zhan-Ao WU
The Chinese Journal of Clinical Pharmacology 2016;32(1):72-74
Objective To explore the clinical effects of two doses of atorvastatin in patients with acute ischemic stroke .Methods A total of 128 patients with acute ischemic stroke were randomly divided into two groups ,64 cases in each group .The patients in atorvastatin 20 mg group were given atorvastatin 20 mg daily , and the patients of the atorvastatin 10 mg group were given atorvastatin 10 mg daily.The treatment lasted for six months.Blood lipid , nerve function defect grading , atherosclerotic plaque area and adverse drug reactions were observed before and after six months.Results The total effective rate in the atorvastatin 20 mg group (98.4%) was significantly higher than that in the atorvastatin 10 mg group (84.4%) (P<0.05).Blood lipid, nerve function defect grading and atherosclerotic plaque area were obviously improved in two groups (P<0.05), and the atorvastatin 20 mg group had a better improvement against the atorvastatin 10 mg group ( P <0.05 ) . The incidence of adverse drug reactions in two groups were 4.7%, no statistical signifi-cance (P>0.05).Conclusion Aatorvastatin 20 mg can better improve the clinical symptoms , blood lipid level as well as atherosclerotic plaque area in patients with acute ischemic stroke , accordingly improve the quality of life in those patients .