With Indian ink vasoperfusion and microangiography,the vessel rebuilding in fresh xenogenic bone graft of 33 rabbits,which had been given glucocortiocoid for a short period of time has observed.The results were as follows:(1)The vessel rebuilding ofxenogenic bone marrow was formed by the hostbone vessel growing in, however,that of the compact bone was formed by the inward penetration of the vessels from the host periost.(2)with glucocorticoid having been used for a short period of time,the vessel rebuilding rate was almost the same between fresh xenogenic bone and autogenic bone.(3)Vessel invasion which happened before osteogenesis regulated osteogenic action. The vessel invasion of different or- igins and under different conditions may have different influence on osteogenesis and osteolysis.

Objective To evaluate the effects ofYinhuangdecoction and external application ofXilei decoction in treating vesicular stomatitis.Methods From January 2012 to October 2013, 126 enrolled cases were randomly divided into a treatment group and a control group with 63 in each. The treatment group, which was treated with acycloguanosine tablets as the control group did, was additionally given orallyYinhuang decoction and external application ofXilei decoction. The symptoms, clinical effects comparison were observed before and after the treatment.Results After 7-days treatment, the cure rate of the treatment group was 95.2%(60/63), and the control group was 73.0%(46/63). Their difference was conspicuous(χ2=17.407,P<0.05). The treatment group attained better curative effects(P<0.05) and got shorter symptomatic relief time of the duration of fever, time of tain disappeared, time of ulcer dissipated and cure time(The T-value is respectively 9.590, 6.983, 5.864, 5.814,P<0.01).ConclusionsYinhuang decoction and external application ofXilei decoction is effective for treating vesicular stomatitis.

It is generally accepted that Kasai operation is the best treatment for biliary atresia (BA). The implementation of early screen plan improves the age threshold at the suitable time point of Kasai operation. This is the key issue to improve the survival rate of autologous liver in biliary atresia. The monitoring of stool color card, B-ultrasonography and serum con?jugated bilirubin can be used for preliminary seeming biliary atresia. It is very important to improve the ability of basic unit medical staff for major improvements to the understanding of the significance of biliary atresia. In some country and district, the local government has put the screen list for BA into healthcare booklet for children. Thus, it has a significant impact of early screen plan on the diagnosis and treatment of BA, and it can improve the BA autologous liver survival time. So far, there is still no BA early screen plan in the nationwide. We should pay attention to BA, and establish early screen system in different local health unit quickly.

Objective To explore the clinical application of array comparative genomic hybridization (aCGH) and karyotype a-nalysis in the prenatal evaluation of fetal with small supernumerary marker chromosome (sSMC) .Methods One case was indenti-fied with de novo small supernumerary marker chromosome .G-banding analysis indicated that the fetus had a karyotype of 47 , XY ,+Mar .aCGH was used to define the precise location and size of de novo chromosome .Results aCGH revealed that there was 2 .03 Mb duplication from 15q11 .1-q11 .2 in the fetus .aCGH revealed the presence of small supernumerary marker chromosome . Conclusion The technologies of aCGH can be used for identifying the origin of small supernumerary marker chromosome and defi-ning the loci of the chromosome .Combined with the karyotype analysis ,it can be applied to genetics analysis and prenatal diagnosis .

Objective　To evaluate the diagnosis and tre atment of testicular torsion.　Methods　18 cases of testic ular torsion were reviewed and reported.　Results　The tes ticles of 5 cases with short time or incomplete torsion were salvaged by operati ve detorsion.The testicles of 13 cases with testicular necrosis were removed (re moval rate 70%).　Conclusions　Testicular torsion has to b e diagnosed correctly on time and the detorsion has to be performed early.For di agnosis of testicular torsion color-Doppler ultrasonography image is a reliable method.Preventive orchiopexy has to be performed in order to avoid recurrence o r relapse.

Objective To compare and analyze the efficacy and safety of amisulpride and risperidone in the treatment of patients with first -episode schizophrenia(FES).Methods 80 patients with FES were randomly divided into the observation group (n =40,orally given amisulpride)and the control group (n =40,orally given risperidone) according to random number table.The total effective rate,positive and negative symptoms scale (PANSS),adverse reaction rate of two groups were compared.Results 1 week after treatment,the negative symptoms score of the observation group was significantly lower than that of the control group [(20.89 ±3.07 )points vs.(18.15 ± 3.64)points,t =3.639,P =0.001].8 weeks after treatment,the PANSS scores and factor score of the two groups had no significant differences(all P >0.05).The total effective rate and adverse reaction rate of the observation group were 90.00%,17.50% respectively,which of the control group were 82.50%,27.50% respectively,there were no statistically significant differences (χ2 =0.949,P =0.330;χ2 =1.147,P =0.284).Conclusion Amisulpride and risperidone has similar efficacy and safety in the treatment of patients with FES,but amisulpride has better early effect in improving negative symptoms.

Because of the medical industry valla,the medical market is in a state of oligopoly.Hospitals and patients are in a state of asymmetric information in the medical market,which could lead to moral hazard,adverse selection,and low social and medical efficiency.Based on the gaming model,we analyze the gaming process and equilibrium between hospitals and patients under the circumstances of asymmetric information.The analyzing result suggests that asymmetric information in the medical market is harmful for patient's benefit and the development of medical market as well.Therefore,it's necessary to strengthen the entire social medicare,set up an opening system of medical information and strengthen the national health education so as to relieve the asymmetric information between hospitals and patients,and improve the efficiency of medical market.

0.997 3) and their average recovery rates were all above 91.3% (RSD

OBJECTIVE:To investigate the stability of reduced glutathione for injection after mixing with inosine and glucose injection in order to provide evidence for clinical rational drug use.METHODS:HPLC was employed to determine the content change after mixing reduced glutathione for injection with inosine and glucose injection,and the change of the mixture in appearance,pH and insoluble particles were also observed.RESULTS:There was little change in appearance,pH and content within 6 h after mixing,insoluble particles were obvious in the first 4 hours.CONCLUSION:Reduced glutathione for injection can be mixed with inosine and glucose injection for use,and it is better for the mixture be used within 4～6 h.

Objective To study the expression of nitric oxide synthase (NOS) during the development of rat colorectal carcinoma. Methods Rat colon carcinoma was induced by injection of 1,2- dimethylhydrazine (1,2-DMH).The expression of eNOS, nNOS and iNOS in normal colon mucosa and colorectal carcinoma was observed by immunohistochemistry. ResultseNOS and nNOS were expressed in normal mucosa. Neither eNOS nor nNOS alterations were observed in carcinoma tissues,iNOS expression was very strong in carcinoma samples(87%)and only 10% in normal colon mucosa. ConclusionOur results show that iNOS may play an important role in the 1,2-DMH induced colon tumorigenesis.