1.The clinical significance of monitoring of coagulation and fibrinolysis related indexes after hip replacement for preventing and diagnosing lower extremity deep venous thrombosis
International Journal of Laboratory Medicine 2015;(23):3453-3454
Objective To evaluate the clinical significance of monitoring of D‐dimer ,fibrinogen and fibrin degradation products after hip replacement for diagnosing and preventing the lower extremity deep venous thrombosis .Methods A total of 66 cases of patients who carried out hip replacement from April 2013 to April 2015 in the department of orthopaedic in this hospital were se‐lected .Patients complicated with lower extremity deep venous thrombosis were enrolled into the observation group ,while patients without lower extremity deep venous thrombosis were enrolled into the control group .Levels of D‐dimer ,fibrinogen and fibrin deg‐radation products were strictly monitored after hip replacement and were comparatively analysed .Results There were no statisti‐cally significant differences in levels of fibrinogen and fibrin degradation products between the two groups (P>0 .05) ,while statisti‐cally significant difference was found in level of D‐dimer between the two groups(P<0 .05) .Conclusion The monitoring of D‐di‐mer ,fibrinogen and fibrin degradation products after hip replacement could have clinical significance for diagnosing and preventing lower extremity deep venous thrombosis .
2.An Analysis of the Gaming between Patients and Hospitals under the Circumstances of Asymmetric Information
Chinese Medical Ethics 1996;0(01):-
Because of the medical industry valla,the medical market is in a state of oligopoly.Hospitals and patients are in a state of asymmetric information in the medical market,which could lead to moral hazard,adverse selection,and low social and medical efficiency.Based on the gaming model,we analyze the gaming process and equilibrium between hospitals and patients under the circumstances of asymmetric information.The analyzing result suggests that asymmetric information in the medical market is harmful for patient's benefit and the development of medical market as well.Therefore,it's necessary to strengthen the entire social medicare,set up an opening system of medical information and strengthen the national health education so as to relieve the asymmetric information between hospitals and patients,and improve the efficiency of medical market.
3.Factors of psychosis in the patients after the esophagus carcinoma resection
Journal of Chongqing Medical University 2003;0(06):-
Objective:To find out the high risk factors of psychosis in the patients after the esophagus carcinoma resection.Methods:We diagnose psychosis disease though the symptom of the patients.900 patients of esophagus carcinoma,who occurred psychosis after the esophagus carcinoma resection,were compared with those who didn't occurred.Results:Some problems in cognition,emotion,action and consciousness were found.The incidence of the psychosis after esophagus carcinoma resection was not correlated with the different gender and different modus operandi,but significantly correlated with the age,the time in ICU after operation and the time that the patients gave up smoke and wine before the operation.Conclusion:The high risk factors in the patients of esophagus carcinoma after operation with psychosis maybe include the age,the time in ICU after operation and the time that the patients gave up smoke and wine before the operation.We should frome these sides to take more care for these patients in our work.
4.A novel ceramide from starfish Asterias rollestoni Bell—rollceramide A
Chinese Journal of Marine Drugs 2000;0(06):-
Objective To study the chemical constituents of starfish Asterias rollestoni Bell.Methods The constituents were isolated by chromatography methods and identified by spectroscopic and chemical analyses.Results and Conclusion A novel compound was obtained and identified as(2S,3S,4R)-2-(13'-methyl-pentadecanoylamino)-nondecane-1,3,4-triol.The compound was reported first time and named as rollceramide A.
5.Effects of Chrysophanol on Learning and Memory Impairment Induced by Sesflurane in Aged Rats
Herald of Medicine 2017;36(4):385-389
Objective To investigate the influence of inhalation anesthestic desfluran (Des) on the learning and memory abilities of rats and the protective role of chrysophanol.Methods Totally,50 male and 50 female rats,aging 24 months and weighing (500 ± 10) g,were randomly divided into five groups:normal control group,Des group,low-,mediumand high-dose Chr group (0.1,1.0 and 10.0 mg·kg-1),with 20 rats in each group.After anesthetization for 24 h,the Morris water maze was used to investigate the abilities of learning and memory of rats.The amount of Aβ1-42 was determined by ELISA assay,and the apoptosis of rat hippocampal neurons in five group was observed by TUNEL assay.Furthermore,the expression levels of Bcl-2,Bax and Caspase-3 were examined by Western blotting.The activity of acetylcholinesterase in each rats hippocampus was determined using iron trichloride chromogenic spectrophotometer colorimetric analysis method.Results Compared with the normal control group,the mean escape latency of the rats in Des group was significantly prolonged;the spatial exploring time (29.85 ± 4.51) s was reduced;the apoptotic rate of neurons (0.742 ± 0.052)%,the amount of Aβ1-42 peptide (9 618.72 ± 1 076.43) pmol· g-1,the expression levels of Caspase-3 (1.132 ± 0.217),and Bax (1.298 ± 0.209) were increased;the expression of Bcl-2 (0.318 ±0.038) were reduced;the activity of acetylcholinesterase (96.38 ±7.62) U·mL-1 was increased.Compared with the Des group,the rats in all Chr groups obtained shorter escape latency and longer spatial exploring time;the amount of Aβ1-42 peptide and the expression levels of Caspase-3 and Bax were down-regulated;the activity of acetylcholinesterase was reduced.In addition,chrysophanol improved the abilities of learning and memory of anesthetic rats in a dose-dependent manner.Conclusion Chrysophanol could improve the abilities of the learning and memory of rats after desflurane anesthesia,along with inhibition of Aβ deposition.
6.Awareness of the subjectivity of non-English major students of medical universities in translation teaching
Chinese Journal of Medical Education Research 2003;0(04):-
This paper,through comparative analysis,studies the features of non-English major students of medical universities as the translation subjectivity in translation teaching,in the hope that it will provide translation teaching with pertinent reference.
7.The Problems of The Vessel Rebuilding in Fresh Xenogenic Bone Graft with Glucocoticoid Used for A Short Period of Time
Journal of Kunming Medical University 1986;0(04):-
With Indian ink vasoperfusion and microangiography,the vessel rebuilding in fresh xenogenic bone graft of 33 rabbits,which had been given glucocortiocoid for a short period of time has observed.The results were as follows:(1)The vessel rebuilding ofxenogenic bone marrow was formed by the hostbone vessel growing in, however,that of the compact bone was formed by the inward penetration of the vessels from the host periost.(2)with glucocorticoid having been used for a short period of time,the vessel rebuilding rate was almost the same between fresh xenogenic bone and autogenic bone.(3)Vessel invasion which happened before osteogenesis regulated osteogenic action. The vessel invasion of different or- igins and under different conditions may have different influence on osteogenesis and osteolysis.
8.Determination of Residue Levels of Organic Solvents in Docetaxel by Head Space GC
China Pharmacy 2007;0(25):-
0.997 3) and their average recovery rates were all above 91.3% (RSD
9.Compatibility of Reduced Glutathione for Injection with Inosine and Glucose Injection
China Pharmacy 2007;0(32):-
OBJECTIVE:To investigate the stability of reduced glutathione for injection after mixing with inosine and glucose injection in order to provide evidence for clinical rational drug use.METHODS:HPLC was employed to determine the content change after mixing reduced glutathione for injection with inosine and glucose injection,and the change of the mixture in appearance,pH and insoluble particles were also observed.RESULTS:There was little change in appearance,pH and content within 6 h after mixing,insoluble particles were obvious in the first 4 hours.CONCLUSION:Reduced glutathione for injection can be mixed with inosine and glucose injection for use,and it is better for the mixture be used within 4~6 h.
10.Studies of AgNOR in Breast Tumor by Frozen Sections, Imprints and Ultrastructures
Academic Journal of Second Military Medical University 1981;0(04):-
23 freshly removed breast tumors without any therapy were studied. Argyrophlilic nuclcolar organizer region proteins (AgNORs) were observed by frozen sections and imprints and the distribution and shape of some AgNORs were analyzed by means of electron microscope. It was found that AgNORs in benign lesions showed regular dotted granules and mean individual counts were significantly fewer (3.33?1.19) than that (9.21?1.24) ( P