OBJECTIVE:To analyze the problems about the prescription review by the monitoring system for rational drug use (PASS 1.6.1.7) and discuss the countermeasures. METHODS:A retrospective method was adopted. A total of 4 942 prescriptions of our hospital in the first quarter of 2015 were selected at random,and reviewed by PASS and the pharmacist respectively. The re-view results were analyzed,and then countermeasures were put forward for the problems found to exist in the software review. RE-SULTS & CONCLUSIONS:The conformity rates of prescriptions which had been determined as acceptable through PASS review and pharmacist review were 81.20% and 97.40% respectively. PASS misjudged 929 (18.80%) rational prescriptions as irrational ones,mainly concerning administration and dosage,simultaneous existence of Western medicine and Chinese patent medicine on one prescription,repeated drug use and use with caution,etc. PASS misjudged 122(2.47%)irrational prescriptions as rational pre-scriptions,mainly concerning administration and dosage,inconformity between diagnosis and drug use,etc. The above-said prob-lem was attributed to imperfect hospital management and insufficient software intelligence. It is suggested that the hospital should strengthen the data maintenance and management of information system and PASS developer should improve software rules to in-crease the accuracy rate of prescription review.

OBJECTIVE:To provide reference for the rational use of haemocoagulase hemostatic drugs in the clinic by under-standing the perioperative utilization. METHODS:In retrospective study,1 200 discharge records of perioperative prophylactic ap-plication of haemocoagulase hemostatic drugs were collected randomly during Jan.-Dec. 2014.,and then analyzed statistically in re-spects of consumption sum and amount,application,irrational drug use,etc. The cost of hemocoagulase accounted for 7.39% of total drug cost,among which Haemocoagulase agkistrodon for injection had the highest consumption amount and sum,with utiliza-tion ratio of 51.44%. Average medication time of hemocoagulase during perioperative period was 2.36d;maximal average cost of hemocoagulase was 684.52 yuan in ENT and head and neck surgery department/ stomatology department;ENT and head and neck surgery department/ stomatology department,urinary surgery department had long average medication time,being 3.85d and 3.50d. RESULTS:Only 39.42% haemocoagulase hemostatic drugs were reasonably used during perioperative period. The unreasonable manifestation included:improper medication time(52.15%), too long medication course after operation(35.75%),wrong usage (5.61%)and replacing various haemocoagulase hemostatic drugs without reason(5.06%). CONCLUSIONS:The striking phenome-non of irrational use of haemocoagulase hemostatic drugs during perioperative period is severely worrying,so we need to strength-en the standard management and pharmaceutical supervision and intervention by clinical pharmacists.

Objective To investigate the application effects of extended care plan in patients with stroke based on evidence-based nursing. Methods A total of 130 patients who met inclusion criteria were selected and received matched groups. The patients of observation group were given the implementation of evidence-based extended nursing plan, while the patients of control group were provided telephone follow-up 1 month after discharge. We compared differences in the ability of daily life ( Barthel index) and health behavior ( HPLP Ⅱ) between two groups at the patients discharged from hospital 1 month, 3 months, 6 months and 12 months. Results Compared between two groups at patients discharged from hospital 3 months, 6 months and 12 months, the differences of Barthel index score were statistically significant ( Ftime=13.389,P<0.05; Fgroup=19.352,P<0.05;Ftime?group=3.416,P<0.05); patients discharged from hospital after 3 months, 6 months and 12 months, the differences of HPLP Ⅱ score were statistically significant between two groups (Ftime=12.187, P<0.05;Fgroup=36.512,P<0.01; Ftime?group=6.692,P<0.01); 3 months, 6 months and 12 months after discharge, the incidences of recurrence were 3. 33%, 10. 00%, 18. 33% in observation group while they were 3.57%, 17.85%, 33.93% in the control group (P<0.01).Conclusions Taking the evidence-based nursing method to develop scientific and normative extended care plan can improve the ability of stroke patients′ daily life and health behavior and reduce the recurrence, which is worth of clinical practice recommendations.