1.Application of ischemia modified albumin and heart-type fatty acid-binding protein for the diagnosis and risk stratification of unstable angina
Zenglian XIN ; Li YANG ; Yuxuan GUO ; Hui PENG ; Feili XU
International Journal of Laboratory Medicine 2015;(16):2346-2348
Objective To determine the value of ischemia modified albumin,heart-type fatty acid-binding protein,B-type natri-uretic peptide and homocysteine in the risk stratification of patients with unstable angina pectoris;thus to provide an assessment for the condition of patients in clinic.Methods 135 patients with unstable angina were included in the disease group and subjected to risk stratification according to GRACE risk score software,70 cases of low-risk group,60 cases in the middle-risk group and 5 cases in the high-risk group.Another 145 healthy people were in the control group.The levels of ischemia modified albumin,heart-type fatty acid-binding protein,B-type natriuretic peptide and homocysteine were detected and compared.Results Between the control group and the disease group,significant difference of heart-type fatty acid-binding protein,B-type natriuretic peptide and homocys-teine was found (P <0.05),but the difference of ischemia modified albumin was not statistically significant(P >0.05).In the dis-ease group,the levels of ischemia modified albumin,heart-type fatty acid-binding protein and homocysteine in each risk stratification showed no significant difference(P >0.05).The level of B-type natriuretic peptide in high-risk group was higher than that in the low-risk group and in the middle-risk group and the difference was statistically significant (P <0.05),while there was no statisti-cally significant difference between the low-risk group and the middle-risk group(P >0.05 ).Conclusion The detection of heart-type fatty acid-binding protein,B-type natriuretic peptide and homocysteine possesses certain meaning in diagnosing unstable angi-na,and the level of B-type natriuretic peptide indicates the risk degree of the disease.
2. Effect of the sleep nursing intervention on sleep status and gross motor development of infants
Chinese Journal of Behavioral Medicine and Brain Science 2019;28(10):881-886
Objective:
To explore the effect of sleep nursing intervention on infants' sleep status and gross motor development.
Methods:
Eighty-nine normal infants aged 8-9 months were randomly divided into two groups: experimental group (
3.Effect of the sleep nursing intervention on sleep status and gross motor development of infants
Chinese Journal of Behavioral Medicine and Brain Science 2019;28(10):881-886
Objective To explore the effect of sleep nursing intervention on infants' sleep status and gross motor development. Methods Eighty-nine normal infants aged 8-9 months were randomly divided into two groups:experimental group (n=45) and control group (n=44). The control group received general fami-ly nursing intervention,while the experimental group received sleep nursing intervention. The whole interven-tion lasted for 56 consecutive natural days. Before and after the intervention,polysomnography ( PSG) was used to monitor the electrophysiology during sleep,and Gesell development assessment scale was used to as-sess the gross motor development of the subjects. Results There were no significant difference in sleep du-ration ((79. 6±15. 0) min,(78. 3± 20. 4) min),REM sleep (( 28. 3 ± 5. 9)%,( 28. 2 ± 9. 0)%),NREM sleep((71. 2 ± 3. 6)%,( 72. 6 ± 5. 1)%),deep sleep (( 13. 0 ± 2. 7)%,( 13. 6 ± 3. 7)%),sleep latency ((9. 1±3. 6)min,(8. 7±2. 9)min)and sleep efficiency ((78. 6±1. 9)%,(84. 4±5. 5)%) before and after the intervention in the control group (all P>0. 05). The sleep duration ((82. 7±13. 4) min,(95. 6±12. 1) min),the proportion of deep sleep (( 10. 4 ± 4. 7)%, ( 16. 6 ± 3. 0)%),the proportion of NREM period ((74. 9±1. 6)%,(76. 9±1. 0)%),the sleep efficiency(( 82. 3± 2. 6)%,(89. 4± 3. 7)%) in the experi-mental group were significantly different before and after the intervention(P<0. 05). The differences value of the total sleep duration,NREM sleep proportion,deep sleep proportion and sleep efficiency before and after the intervention in the experimental group were significantly higher than those in the control group (P< 0. 05). The difference value of gross motor development between the two groups before and after intervention was statistically significant (test group (6. 0±3. 0),control group (2. 0±1. 5),t=4. 687,P<0. 05). Conclu-sion Sleep nursing intervention can improve the proportion of deep sleep in infants and improve the devel-opment level of gross exercise. The community health service can make sleep nursing intervention plan ac-cording to different families and infants' psychological development to optimize infants' deep sleep and pro-mote the level of gross motor development.