Objective To explore the value of the joint space in the prediction and evaluation of cervical vertigo(CV).Methods 45 CV patients were selected in our hospital from May 2011 to March 2015 as the observation group,and 45 healthy people in our hospital were selected as control group in the same period.The differences of atlas axis joint space including the atlantodental interval(ADI),LADI and VBLADI between the two groups were measured by three dimensional CT,evaluated the difference of indexes of joint space,CV symptom and function score of patients in observation group before treatment and 3 weeks after treatment were observed by CV symptom and function assess-ment scale,and analyzed theirs correlation.Results The differences of ADI and VBLADI between the two groups were statistically significant(t =3.430,87.753,all P <0.05 ).The vertigo,neck pain,headache,daily life and psychological of work and social adaptive capacity scores,ADI and VBLADI levels in the observation group were significantly decreased after treatment(t =67.236,31.795,25.198,18.494,19.180,98.194,10.972,75.895,all P <0.05).Correlation analysis showed that the ADI,VBLADI and the indexes scores of CV symptoms and function were positively correlated(r =0.456,0.829,0.578,0.456,0.378,all P <0.05;r =0.512,0.398,0.782,0.412, 0.477,0.891,all P <0.05).Conclusion Axial joint disease is an important factor in the pathogenesis of CV,and there is a significant correlation between the axial joint space and CV,which can be used as a predictive index for the assessment and treatment of patients with CV.

Objective To provide theoretical reference for clinical therapy of pulmonary adenocarcinoma by evaluating the effects of polysaccharides and pioglitazone on mouse model of pulmonary adenocarcinoma and to explore the relationship between inflammation and pulmonary adenocarcinoma. Methods One hundred mice were averagely divided into five groups, including control group, model group, polysaccharides group, pioglitazone group, polysaccharides and pioglitazone group (unite group). Polysaccharides solution (500 mg/kg) was given to polysaccharides group, pioglitazone solution (15 mg/kg) was given to pioglitazone group, polysaccharides solution (500 mg/kg) and pioglitazone solution (15 mg/kg) were given to unite group;and the equal volume of saline (10 mL/kg) was given to control and model group (1 t/d, 5 d/w, continuously 20 w ). The pulmonary adenocarcinoma induced by urethane was evaluated in each group at different time points. The levels of NF-κB, TNF-α, IL-1β and IL-6 were measured in each group at the 12th week and the 20th week respectively. Results The body weights were increased in the control group, which were decreased in other groups during urethane-injection, but increased continuously after the injection. At the 20th week, nodules were found in lung surfaces in all mice except mice of control group. The lung index was higher in all mice except mice of control group. The levels of NF-κB, TNF-α, IL-1βand IL-6 were significantly higher at 12th week and 20th in model group, polysaccharides group, pioglitazone group, polysaccha?rides and pioglitazone group than those of control group. The levels of NF-κB, TNF-α, IL-1βand IL-6 were significantly lower in polysaccharides group, pioglitazone group, polysaccharides and pioglitazone group than those of model group. Con?clusion Sustained inflammatory response is one of the risk factors for the development of lung adenocarcinoma. Polysaccha?rides and pioglitazone can reduce the level of inflammation in mouse lung adenocarcinoma, suggesting that both of them can be used as potential adjuvant in the clinical treatment of lung adenocarcinoma.