Objective To investigate the effect of evidence-based nursing on oral ulcer of leukemia patients undergoing chemotherapy. Methods A total of 60 leukemia patients in our hospital from January 2014 to October 2014 were enrolled as observation group, and given evidence-based nursing intervention including health education, pH adjustment of mouth, mouthwash by ice water, and oral ulcer nursing according to the degree. Clinical data of 60 leukemia patients from April to December 2013 before the implementation of evidence-based nursing( control group) was retrospectively analyzed and the incidence rate and recovery of oral ulcer were compared. Results The incidence rate of oral ulcer in observation group (21. 67%, 13/60) was lower than that in the control group (60. 00%,36/60) (χ2 =5. 964,P<0. 05); the healing time of oral ulcer in the observation group (4.23 ±2.14)d was shorter than that in the control group (7.15 ±2.44)d (t =4. 614,P<0. 05). Conclusions Taking evidence-based nursing in leukemia patients can promote the quality of nursing care, reduce the incidence of oral ulcer, and improve the rehabilitation effect.

Objective To investigate the effect of percutaneous coronary intervention (PCI) on left ventricular remodeling and cardiac function in patients with myocardial infarction.Methods A total of 90 myocardial infarction patients in our hospital were as the research objects,a total of 45 cases underwent PCI surgery were in observation group,another 45 cases undergoing elective PCI surgery were in control group.The levels of N-terminal pro brain natriuretic peptide (NT-proBNP),norepinephrine (NE) and epinephrine (E),plasma renin (PRA),angiotensin Ⅱ (Ang Ⅱ),aldosterone (ALD) were detected before operation and on the first postoperative day.After 6 months of follow-up,the incidence of heart failure of two groups were compared.Results There was no significant difference between the two groups in preoperative NT-proBNP,NE,E,PRA,Ang Ⅱ and ALD levels (P ＞0.05),the observation group had decreased NT-proBNP,NE,E,PRA,Ang Ⅱ,ALD levels at 1 d after operation than operation before and the control group (P ＜ 0.05).At 1 month after surgery,the observation group had lower LVDEd,LVSEd,LAd,and higher LVEF than treatment before and control group (P ＜ 0.05).The incidence of heart failure after 6 months in the observation group and the control group was 1 1.1％,2 4.4 ％ respectively,and the difference was statistically significant (x2 =7.31,P ＜ 0.05).Conclusion Percutaneous coronary intervention (PCI) timing can affect the prognosis of patients with myocardial infarction.Compared with elective PCI,emergency PCI can inhibit the RAAS system and sympathetic activation,improve ventricular remodeling and left ventricular function after myocardial infarction,and reduce the incidence of secondary heart failure.

Objective To investigate the effect of percutaneous coronary intervention (PCI) on left ventricular remodeling and cardiac function in patients with myocardial infarction.Methods A total of 90 myocardial infarction patients in our hospital were as the research objects,a total of 45 cases underwent PCI surgery were in observation group,another 45 cases undergoing elective PCI surgery were in control group.The levels of N-terminal pro brain natriuretic peptide (NT-proBNP),norepinephrine (NE) and epinephrine (E),plasma renin (PRA),angiotensin Ⅱ (Ang Ⅱ),aldosterone (ALD) were detected before operation and on the first postoperative day.After 6 months of follow-up,the incidence of heart failure of two groups were compared.Results There was no significant difference between the two groups in preoperative NT-proBNP,NE,E,PRA,Ang Ⅱ and ALD levels (P ＞0.05),the observation group had decreased NT-proBNP,NE,E,PRA,Ang Ⅱ,ALD levels at 1 d after operation than operation before and the control group (P ＜ 0.05).At 1 month after surgery,the observation group had lower LVDEd,LVSEd,LAd,and higher LVEF than treatment before and control group (P ＜ 0.05).The incidence of heart failure after 6 months in the observation group and the control group was 1 1.1％,2 4.4 ％ respectively,and the difference was statistically significant (x2 =7.31,P ＜ 0.05).Conclusion Percutaneous coronary intervention (PCI) timing can affect the prognosis of patients with myocardial infarction.Compared with elective PCI,emergency PCI can inhibit the RAAS system and sympathetic activation,improve ventricular remodeling and left ventricular function after myocardial infarction,and reduce the incidence of secondary heart failure.