1.A case of guidewire-induced distal coronary perforation treated with microcatheter delivery of intracoronary thrombin.
Shipeng DAI ; Zesheng XU ; Jiangang ZHANG ; Bingxun WANG ; Yongxing LIU ; Ya LI ; Tao GENG ; Yonggang YUAN ; Zengcai MA ; Zhiyuan SONG ; Wanzhong PENG
Chinese Journal of Cardiology 2015;43(1):76-77
2.The impact of different dosages of statins in elderly patients with ST-segment elevation acute myocardial infarction undergoing percutaneous coronary intervention
Hua LIU ; Jiangang ZHANG ; Bing LI ; Deguang WANG ; Zengcai MA ; Zesheng XU
Journal of Clinical Medicine in Practice 2024;28(9):62-66
Objective To investigate the effects of different dosages of atorvastatin, rosuvastatin, and simvastatin in elderly patients with ST-segment elevation acute myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). Methods A total of 180 patients with STEMI undergoing PCI were prospectively selected as study subjects and divided into group A, group B, group C, group D, group E, and group F using a random number table method, with 30 patients in each group. The group A received low-dose simvastatin orally, the group B received high-dose simvastatin orally, the group C received low-dose atorvastatin orally, the group D received high-dose atorvastatin orally, the group E received low-dose rosuvastatin orally, and the group F received high-dose rosuvastatin orally. The levels of serum inflammatory factors[interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), high-sensitivity C-reactive protein (hs-CRP)], myocardial injury markers[creatine kinase isoenzyme (CK-MB), cardiac troponin T (cTnT), N-terminal pro-brain natriuretic peptide (NT-proBNP)], cardiac function indicators[left ventricular ejection fraction (LVEF), cardiac index (CI), cardiac output (CO)], as well as the ST-segment resolution, occurrence of adverse cardiovascular events, and adverse reactions were compared among the groups. Results At 1 day and 1 month postoperatively, the levels of IL-6, hs-CRP, and TNF-α decreased successively in groups A, B, C, D, E, and F(