With the improvement of the therapy and the drugs we known more results in a therapeutic ambitious goals of juvenile idiopathic arthritis.Selection of individualized sequential therapy is beneficial to the recovery of the disease.

OBJECTIVE: To study the protective effects of nimesulide, a COX- 2 selective inhibitor on experimental gastric ulcer in rats. METHODS: The gastric ulcer model was established in rats by intragastric administration them with indometacin, 5 min later, which were assigned to receive nimesulide at different dosages ( 200, 100, and 50mg? kg- 1) , 6h later, all the rats were sacrificed. The primary outcome measures were the area of ulcer, levels of SOD, MDA, and GSH in sera and gastric mucosa. RESULTS: As compared with model group, in nimesulide ( at different dosage) groups, the area of ulcer was markedly decreased, level of MDA was decreased while activities of SOD and GSH were increased ( P

Objective To observe the effect of expelling wind, cooling blood and invigorating kidney prescription on the marrow megakaryocyte differentiation maturity and TGF-β1 in patients with chronic idiopathic thrombocytopenic purpura (CITP). Methods Fifty CITP patients were randomly divided to three groups, including 20 patients administrated with the expelling wind, cooling blood and invigorating kidney prescription as TCM group, 15 patients with the same decoction and prednisone as combine group, and 15 patients with prednisone as western medicine group, 4 weeks as one treatment course. After 3 courses, the change of platelet counts, marrow megakaryocyte amount, platelet-produced megakaryocyte proportion and TGF-β1 level in the marrow were observed. Results The fine efficiency of TCM group (55.0%, 11/20) excelled western medicine group (20.0%, 3/15) significantly and close to that of combine group (60.0%, 9/15). Platelet counts of TCM group was raised obviously after treatment (P<0.01), better than that of western medicine group (P<0.05), and was similar to that of combine group. The marrow megakaryocyte amount of TCM group was effectively decreased and the platelet-produced megakaryocyte proportion was increased greatly (P<0.01), similar to that of combine group, which of western medicine group had no significant difference between pre-therapy and post-therapy. TGF-β1 of TCM group and combine group degraded obviously (P<0.05) compared with that before treatment, and was significant deviation compared with that of western medicine group (P<0.05). Conclusion The expelling wind, cooling blood and invigorating kidney prescription can effectively degrade the value of TGF-β1 of CITP patients, facilitate the maturity of the marrow megakaryocyte amount and raise the platelet counts.

The roles of information section of medical information construction are very important. By combining with the information working experience of hospital,the functions of information section in medical information construction are introduced from five aspects,including the role of decision-making staff,the role of organization and coordination,the role of management support,leading role and the role of information service,which can offer the experience for information construction of the other hospitals.

OBJECTIVE To provide an effective management mode of antisepsis for dental handpiece in dental(hospital) where a system called "one handpiece for one patient" is supposed to be found.METHODS Development and(running) mode of Antisepsis Center for Dental Handpiece were reviewed and function of the Center was(evaluated).(RESULTS) It was found that working process in the outpatient department could be simplified and much labor saved by maintain,antisepsis and refixation for dental handpiece in a wholesale mode.Furthermore,working efficiency and financial benefit of the dental hospital be greatly improved in this mode.CONCLUSIONS Antiseptic quality for dental handpiece is guaranteed by a standardized and programmed sterilization process in the Antisepsis Center for Dental(Handpiece).Management for handpiece in a wholesale mode is quite practicable and scientific.

Standardized management for medical equipment department of the second-class traditional Chinese medical hospital is of great importance to enhance working and economic efficiencies. When standardized management performed, it's suggested that related organization, regulation as well as maintenance and file management be involved in.

Objective To discuss how to deal with the problems of LEEP electro-scalpel that are caused by the burn of negative electrode loose and the electric shock of leakage current.Methods The system's security was enhanced by insulation,power and software control and it was also evaluated.Results The electric leakage of LEEP electro-scalpel was acceptable and the preventive support of burn was effective.Conclusion It is proved by the synthetical evaluation that the device's secure design is reliable.

The test procedure and content of valves pressure test of AK95 hemodialysis machine are mainly introduced.The valves pressure test are the key of the self test procedure in hemsdialysis machine.It is necessary to find the accurate process where problems occur.[Chinese Medical Equipment Journal,2008,29(2):94]

Objective To explore the application of the PRECEDE -PROCEED model on the improvement of junior guide nurses'behavior in service .Methods On the basis of the PRECEDE -PROCEED model, 23 junior guide nurses were accepted standardized training on behavior in service .The condition of junior guide nurses'service principle and behavior in service was investigated by using questionnaires and participant observation ; then we ana-lyzed the trends that influence behavior in service , promoted and strengthened these trends , carried out a complete training plan to provide standardized intensive training and used methods , including self-assessment , continuous su-pervision and timely feedback , to compare patients'and doctors'satisfaction, nurses'knowledge about service princi-ple, self-assessment of behavior in service and the observation of onsite service .Results After the training , the scores, in terms of patients'and doctors'satisfaction, nurses'knowledge about service principle , self-assessment of behavior in service and the observation of onsite service rose obviously .Compared with those before the training , these changes had statistical significance (p<0.01).Conclusion The PRECEDE-PROCEED model can improve junior guide nurses'behavior in service , and improve patients'satisfaction.

In this article,the author introduced their experiences,investigated the importance,connotation,and strategy of aesthetic education to the medical students and put forward some suggestions on aesthetic education in medical education in order to cultivate multiple qualifications of medical students.