Objective To identify the conflict management strategies of staff nurses in Macau. Methods The Thomas -Kilmann Conflict Mode Instrument (TKI)was employed in the study to investigate the conflict management strategies of a convenience sample of 140 staff nurses who were pursuing a Bachelor of Science in Nursing (Supplementary) Programme in Macau. Results The most commonly used strategy by staff nurses in Macau for conflict management was accommodation, followed by avoidance, then compromise. In contrast, the least often used strategy was competition. Conclusions Chinese culture as well as nursing education background should be fully considered when developing the training plan of conflict man -agement strategies for staff nurses in Macau.

Prostasomes are one of the subcellular structures secreted by prostatic epithelial cells.They present in human semen as membranous vesicles with average diameter of 150nm(40-500nm).440 proteins have been identified in human prostasomes and possess many physical functions.Prostasomes may not only exert a motility function for spermatozoa by delaying the acrosome reaction,but also have immune regulatory function,antibacterial and antioxidant characteristics.Prostasomes can be isolated from the serum and urine,and they present both in normal and prostatic cancer tissues.Prostasome can be a special prostatic biomarker and has a close association with prostatitis and prostate cancer.

Objective:To explore the future development of pharmacists. Methods:The combination of on-site and mailed ques-tionnaire was adopted to investigate the present work situation of pharmacists in hospitals at different levels in 15 provinces and munici-palities of east China. Based on the statistical analysis of data, some problems in the present work of pharmacists were investigated. Results:The data showed that there was a wide gap of human resource among the hospitals at different levels, and the working condi-tion improvement for pharmacists should be performed. Continuing education and legislation were not standardized and unified yet, and the clinical pharmacy and the rational drug use needed further development. Conclusion:The relevant laws and regulations should be established and improved to guarantee the lawful right and interests of pharmacists. The pharmacist training system should be improved to raise the professional quality of pharmacists and promote the development of hospital pharmacy.

Anti-Bacterial Agents ; pharmacology ; Child ; Drug Resistance, Bacterial ; genetics ; Humans ; Macrolides ; pharmacology ; Pediatrics ; Streptococcus pyogenes ; drug effects

At present the concept of clinical thinking is reviewed at the narrow senses and there are many limitations.So it is very necessary to understand the concept of clinical thinking at the broad senses.

OBJECTIVE: To optimizate the preparation process of Yuganning patch. METHODS: The preparation process of Yuganning patch was optimzied by orthogonal experiment with content of ointment, setting time, drying temperature and drying time as factors and the initial strength, peeling strength and degumming phenomenon as indexes. RESULTS: The optimum preparaition conditions were as follows: the content of ointment was (7.6?0.1) g?100 cm-2; the setting time was 24 h; the drying temperature was 60 ℃ and drying time was 3.5 h. And this optimized process met quality control method. CONCLUSION: The optimized preparation process is feasible and the quality of the Yuganning patch is stable.

Objective: To establish a HPLC method for the determination of synephrine in Dachengqi Granules (Radix et Rhizoma Rhei, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Natrii Sulfas). Methods: A E. Merck LiChrospher 100RP 18 column was /used. The mobile phase was methanol water (contained 0.18% H 3PO 4 and 0.22% C 12 H 25 SO 4Na) (55∶45). The detection wavelength was at 274nm.Results: The linear range of synephrine was 0.14?g～1.54?g, r =0.9998. The average recovery was 98.1%, RSD =2.1% ( n =5).Conclusion: The result is accurate and the reproducibility is good. This method can be used for the determination of synephrine in Dachengqi Granules.

Objective To compare the effectiveness of propafenone,(intravenous and oral) and lanatoside C in reversing atrial fibrillation (AF) and their safety in non-rheumatic patients.Methods Ninety-seven recent onset(≥0 5h～41days) AF patients were included. Subjects with valvular heart disease, heart failure (NYHA heart function≥Ⅲ degree),myocardial infarction, sick sinus syndrome, atrioventricular block(≥Ⅱ degree), preexcitation syndrome and hyperthyroidism were excluded. Three groups were subdivided according to the results:⑴ The group of intravenous propafenone(groupⅠ):thirty-three patients were given intravenous injection propafenone 70 mg within 7 minutes, the non-converted patients were given another 140 mg (0 5～1mg/min) intravenous infusion. ⑵The group of oral loading dose propafenone: Thirty-two patients were given propafenone 450 mg orally(groupⅡ).⑶The group of intravenous lanatoside C(groupⅢ):Thirty-two patients were given intravenous lanatoside C 0 4 mg within five minutes and another 0 2 mg must be added to if AF was not reversed in 4 hours. EKG, blood pressure, symptoms, AF reversing and ventricular rate were closely observed under heart monitoring all patients. The time from intravenous injection or receiving the drug to reversing the AF to sinus rhythm was recorded. Observing the reversal rate and time of the three groups of patients for 30 minutes,1h, 2h, 4h, 8h respectively, we could get the results as follows.Results Average reversal time is: group Ⅰ (0 8?0 4)h, group Ⅱ(4 1?1 8)h. group Ⅲ(3 7?2 0)h, There was a prominent difference (P0 05).Conclusion Of the above three methods in reversing AF, the average reversal time of intravenous propafenone is the shortest, and the have the most efficient reversal rate.

Methamphetamine is a powerful stimulant of amphetamine type in the central nervous system (CNS),and recently it has become the major drugs of abuse.A lot of research results show that MA may induce dopaminergic neurotoxicity in the animal and human striatum.The mechanisms include effects on dopaminergic signaling and dopamine oxidation,glutamate induced excitotoxicity,oxidative stress and inflammatory cytokines,disruption of mitochondfia,apoptosis,activation of glial cells and hyperthermia.However the mechanisms by the MA-induced dopaminergic neurotoxicity are not completely understood.The paper reviewed recent progress of study on them to provide reference materials for related research.

Gene Expression Profiling ; Genomics ; methods ; Humans ; Lymphoma, Large B-Cell, Diffuse ; classification ; genetics ; pathology ; Prognosis