1.A Controlled Study of Personality Characteristics and Personality Disorders of Patients with Major Depression and Dysthymic Disorders in Remission
Chengge GAO ; Zanli WANG ; Shumao JI
Chinese Journal of Clinical Psychology 2001;0(03):-
Objestive:To explore the personality traits of patients with major depression and dysthymic disorder in remission and to determine the difference of dimension ,trait level ,model of personality and personality disorder between depressive and normal subjects.Methods: major depression patients( MDD, n =58) and dysthymic disorder patients(DD, n =57) in remission and controls( n =115) were assessed with Revised NEO Personality Inventory(NEO-PI-R) and Personality Diagnostic Questionnaire( PDQ +4 ) .Results:The mean scores of Extroversion and Conscientiousness of five-factor personality model of NEO-PI-R in MDD and DD were significantly lower than those of normal group. The scores of Neuroticism of DD were significantly higher than those of MDD. The scores of Agreeableness of MDD were significantly higher than those of normal groups;The difference of thirty traits personality model had statistical significance between depressives and normal subjects. The scores of Anxiety(N1) and Self-Consciousness(N4)of DD were significantly higher than those of MDD. The scores of Activity(E4) and Trust(A1)of DD were significantly lower than those of MDD;The mean scores of 7 subscales of PDQ +4 in depression group were significantly higher than those of normal group . The scores of Schizotypal personality disorder of DD were significantly higher than those of MDD, The scores of Hysteria personality disorder of DD were significantly higher than those of normal group.Conclusion: The major depressive and dysthymic disorder patients in remission showed the differences of dimension ,trait level ,and model of personality.The personality disorder of DD was more than those of MDD.
2.A controlled study of personality characteristics of mental disorders by NEO-PI-R
Chengge GAO ; Zanli WANG ; Ce CHEN ; Xiancang MA ; Shumao JI
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To explore the personality characters of patients with mental disorders and to determine the differences of dimension,trait level and model of personality between patients and normal subjects.Methods The patients with mental disorders(n=376) and normal subjects(n=368) were assessed with revised NEO personality inventory(NEO-PI-R).Results The mean scores of extroversion(E) and conscientiousness(C) of five-factor personality model of NEO-PI-R in patients were significant lower than those in normal group((P
3.APOPTOSIS AFTER SPINAL CORD INJURY IN RATS
Zanli JIANG ; Junchang CHEN ; Kunzheng WANG ; Bing BAI
Journal of Pharmaceutical Analysis 2000;12(1):55-57
Objective To confirm the role played by apoptosis in spinal cord injury. Methods 36 rats models of spinal cord injury were made by Allen method. Histological examinations using HE staining and in situ end-labeling were used to observe apoptosis in spinal cord tissues from 1h to 21d after injury. Results HE staining sections showed hemorrhage and necrosis, neuronal degeneration and gliai cell proliferation. In situ end-labeling sections showed the appearance of apoptosis in both gray and white matter as well as in both central and surrounding region. The number of apoptotic cells increased from 12h after injury, increased to the peak at 4d and declined to normal at 21d. Conclu sion The results suggest that apoptosis, especially glial apoptosis, plays a role in the pathogenesis of spinal cord in jury.
4.Efficacy of percutaneous nephrolithotomy combined with ureteroscopy guided by ultrasound in treatment of renal staghorn calculi
Zanli WANG ; Fuqing WAN ; Ziyi FENG ; Xuechong ZHANG
China Modern Doctor 2015;(22):43-46
Objective To analyze the efficacy of percutaneous nephrolithotomy (PCNL)combined with ureteroscopy in treatment of renal staghorn calculi. Methods The data of 126 patients with renal staghorn calculi were retrospectively analyzed in the department of urinary surgery of our hospital. All patients were treated with PCNL combined with ureteroscopy. The related data of preoperative, intraoperative and postoperative were recorded and analyzed. Mean-while, 89 patient with renal staghorn calculi treated by PCNL were selected as control group. The related parameters between two groups were compared. Results Compared with control group,the operation time, amount of bleeding and complication rate of PCNL combined with ureteroscopy group were lower(P<0.05), the stone clearance rate of PCNL combined with ureteroscopy group was higher(P<0.05). Among of PCNL combined with ureteroscopy group,27 patients suffered from fever after surgery and 1 patient had hemorrhage. No renal collection system tear or perforation,damaged pleura, bowel and major vessel occurred. 15 patients had residual stones and were treated by two-stage operation. 48 cases were followed up from postoperative 6-36 months and there wasn't stone recurrence. Conclusion PCNL com-bined with ureteroscopy guided by ultrasound is a good choice in treatment of renal staghorn calculi.