1.Relationship between Nutritional Status, Physical Activity and Quality of Life among Gastrointestinal Cancer Survivors
Zalina AZ ; Lee VC ; Kandiah M
Malaysian Journal of Nutrition 2012;18(2):255-264
Introduction: The objective of this study was to determine the relationship between nutritional status, physical activity and quality of life among
gastrointestinal cancer survivors. Methods: A cross-sectional study was conducted among gastrointestinal cancer survivors attending the oncology outpatient clinic
in Hospital Selayang, Malaysia. Results: A total of 70 gastrointestinal cancer survivors with a mean age of 52.54 ± 14.59 years (95% CI: 47.48 – 57.60) were
included in this study. Results showed that 40% of the patients were classified as having low physical activity. The mean Patient Generated Subjective Global
Assessment (PGSGA) score was 10.27 ± 7.36 (95% CI: 8.23 – 12.31) and nearly half the patients (48.6%) were identified as severely malnourished (Stage C). Mean
Gastrointestinal Quality of Life Index (GQLFI) score was 103.57 ± 23.85 (95% CI:92.94 -114.20), and about 24.3% of the patients were classified as having a low
quality of life. Pearson’s correlation test showed a highly significant negative relationship between nutritional status and quality of life (r=-0.661, p<0.001)
indicating the better the nutritional status (low total mean score of PGSGA), the better the quality of life of the survivors (high total mean score of GQLFI). There
was a significant negative relationship between physical activity level and nutritional status score (r=-0.309, p<0.01), indicating the higher the physical
activity level of the patients (high MET-min/week), the better their nutritional status (low total mean score of PGSGA). Conclusion: This study shows a significant
relationship between nutritional status, physical activity and quality of life among gastrointestinal cancer survivors. Those low in nutritional status have a low
quality of life while survivors with higher nutritional status have a better quality of life.
2.Assessing the Nutritional Status of Children with Leukemia from Hospitals in Kuala Lumpur
Zalina AZ ; Suzana Shahar ; A Rahman A Jamal ; Noor Aini MY
Malaysian Journal of Nutrition 2009;15(1):45-51
A cross-sectional study was carried out to evaluate the nutritional status of 51 subjects
with leukemia aged 4 to 12 years from the Haematology & Oncology Paediatric Ward,
Universiti Kebangsaan Malaysia Medical Centre (PPUKM) and the Paediatric Institute of Kuala Lumpur. Nutritional status was assessed using anthropometric measurements,
biochemical and haematological parameters. Subjects comprised 32 (62.7%) males and
19 (27.3%) females. Most of the subjects (41.2%) were in the age group of 4 to 6 years.
More than half of the children were Malays (70.6%) followed by Indians (15.7%) and
Chinese (13.7%). The subjects were diagnosed as acute lymphoblastic leukemia (ALL)
(84.3%) followed by acute myelogenous leukemia (AML) (13.7%) and chronic myelogenous leukemia (CML) (2.0%) respectively. Most of the children were in
remission status (54.9%). Underweight (<-2 SD for weight-for-age) was observed in
37.3% of the children while 17.6% of them were stunted (<-2 SD for height-for-age), and
sign(s) of malnutrition (<-2 SD) for mid upper arm circumference (MUAC)-for-age was
observed in 15.7% of the subjects. Approximately 20.0% of the subjects were in the
severe malnutrition category with respect to low serum albumin levels (<3.5g/dl). All
subjects had hemoglobin levels of less than the normal range. While the results indicated
no significant differences in the nutritional status of subjects with leukemia at different
stages of treatment, it was observed that the prevalence of malnutrition was higher in
children with newly diagnosed leukemia. Thus, the nutritional status of children with
leukemia should be monitored closely as there is a likelihood of deterioration owing to the disease.