1.Cost-effectiveness Analysis of PIVAS in Our Hospital
China Pharmacy 2016;27(10):1430-1432
OBJECTIVE:To investigate the revenue and expenditure in PIVAS of our hospital,and to provide data for the es-tablishment and operation of PIVAS in other hospitals. METHODS:A statistics was undertaken for the revenue and expenditure of PIVAS in 2014,and partial influential factors were analyzed comprehensively. RESULTS:In 2014,under the premise of only long-term doctor's advice for the morning,760611 groups of intravenouse drugs had been administered in PIVAS of our hospital. The revenue was about 2197439 yuan and the expenditure was about 1872598 yuan;the cost of human resource was the main cost part,which took 77.92%. CONCLUSIONS:The revenue of PIVAS almost covers the cost of pharmacy in our hospital at pres-ent;the data of cost-effectiveness can be reference for other hospitals.
2.Sequential bilateral lobar transplantation A case report
Zhenrong ZHANG ; Deruo LIU ; Yongqing GUO ; Bin SHI ; Zhiyi SONG ; Yanchu TIAN ; Yanning SHOU ; Chaoyang LIANG ; Haitao ZHANG ; Jingyu CHEN ; Zaiyong WANG ; Tong BAO ; Qianli MA ; Guangliang QIANG ; Hongxiang FENG
Chinese Journal of Tissue Engineering Research 2010;14(53):10067-10070
BACKGROUND: Lung transplantation can improve quality of life of patients who get terminal pulmonary disease and also it can help to get better survival.Now it has become one of the best therapeutic methods for terminal pulmonary disease.However,limited donors leave the development of lung transplantation in dilemma.The emergence of living lobar transplantation and cadeveric lobar transplantation let this procedure much easier.OBJECTIVE: To evaluate the clinical probability of bilateral lobar transplantation.METHODS: Sequential bilateral lobar transplantation was performed for one 26 years old cystic fibrosis female.Cardiac pulmonary bypass was used during operation.Anti-rejection(Tacrolimus,mycophenolate,etc)and anti-infection was used postoperatively.RESULTS AND CONCLUSION: The recovery course postoperatively was smooth,and the recipient got out of hospital 7weeks later.Bilateral lobar transplantation could offer satisfied short-term pulmonary function.The long term results should be further evaluated.
3.Allogeneic single lung transplantation in 7 cases
Deruo LIU ; Yongqing GUO ; Fengrui ZHAO ; Futian LI ; Bingsheng GE ; Bin SHI ; Yanchu TIAN ; Zhiyi SONG ; Yanning SHOU ; Haitao ZHANG ; Chaoyang LIANG ; Zaiyong WANG ; Jingyu CHEN ; Tong BAO ; Zhenrong ZHANG ; Yuling XIN
Chinese Journal of Tissue Engineering Research 2008;12(53):10567-10570
The present case report was designed to summarize the clinical experience of operative technique. lung preservation, lung perfusion, and perioperative management. Of 7 cases who underwent allogenic single lung transplantation (LT), 3 were idiopathic pulmonary fibrosis, 2 were chronic obstructive pulmonary disease, 1 was silicosis, emphysema, and bulla, and I was tuberculosis in both sides and presented with destroyed lung in one side. All donors were already brain death. Donor lungs were well preserved utilizing Euro-Colins liquid or low-potassium dextran solution. Donors and recipients were matched in blood type. Of 7 cases selected,5 received single right lung transplantation, and 2 received single left LT. End-to-end anastomosis was performed for pulmonary branches and pulmonary arteries. while atrium-to-atrium anastomosis was performed for pulmonary vein. Antibiotics and immunosuppressants were routinely used prior to and subsequent to LT. Following LT, heart and lung function, usage of antibiotics, and adjustment of immunosuppressant were monitored. Stomal complications regarding bronchus and pulmonary artery and vein did not appear in any patient. Five cases survived for about 2 months, one for approximately 1 year, and one for nearly 2 years. Four cases died of multi-organ failure caused by pulmonary infection, and one of severe pulmonary hemorrhage caused by aspergillus sydowi infection. Rejection occurred in 6 cases. One case sufiered from rejection three times. Selection of indication, selection and preservafton of donor lung, LT operation and pre-and post-operative management of LT have acquired satisfactory achievements. High mortality occurred in patients with preoperative poor cardiac and pulmonary functions and postoperative severe infections accompany with application of immunosuppressant.
4.Late-stage emphysema treated with lung volume reduction: report of 22 cases.
Fengrui ZHAO ; Deruo LIU ; Bin SHI ; Yanchu TIAN ; Zaiyong WANG ; Tong BAO ; Futian LI ; Yongqing GUO ; Haitao ZHANG ; Jingyu CHEN ; Bingsheng GE
Chinese Journal of Surgery 2002;40(3):194-197
OBJECTIVETo Summarize the clinical experience in the treatment of late-stage emphysema by lung volume reduction (LVR) in 5 years.
METHODSWe retrospectively studied the indications, contraindications, operation procedures and complications of LVR in 22 patients.
RESULTSBefore operation, the average FEV(1) was 24.5%, RV 196.8%, and TLC 130.5%; after operation they were 27.8%, 148.8% and 112.5%, respectively. 16 patients needed inhaling oxygen before operation, and 5 after operation. 16 patients finished 6-minute walking test with an average of 198 m, all patients walked much longer with an average of 256 m after operation. 3-degree lung function was observed in 14 patients, and 4-degree before operation in 8 patients; but 2-degree lung function in 5 patients, 3-degree in 13, and 4-degree in 4 after operation.
CONCLUSIONSHeterogeneous type emphysema with clear target area, especially bullous emphysema is the best indication for LVR. Lung function and life quality could be much improved postoperatively. Homogeneous type could also be treated with LVR in highly selected cases. TLCO < 20% is not an absolute contraindication, others standards need further investigation. Video-assistant thoracoscopic surgery (VATS) with subaxillary small incision for LVR is safe, reliable and effective. Application of stapler buttressing with bovine pericardia could decrease air leakage postoperatively.
Aged ; Female ; Humans ; Male ; Middle Aged ; Pneumonectomy ; Pulmonary Emphysema ; surgery ; Retrospective Studies ; Thoracoscopy
5.Analysis of primary site and pathology on 903 patients with neuroendocrine neoplasms.
Xudong QIU ; Meng LIU ; Qing LIU ; Zhiying YANG ; Jixi LIU ; Fanqiang MENG ; Zaiyong WANG ; Yanfen SHI ; Liguo LIU ; Pan ZHANG ; Jie LUO ; Huangying TAN
Chinese Journal of Gastrointestinal Surgery 2017;20(9):993-996
OBJECTIVETo explore the primary site and pathological feature of neuroendocrine neoplasm (NEN), especially the NEN of digestive system.
METHODSClinicopathological data of NEN patients at China-Japan Friendship Hospital from January 2012 to December 2016 were retrospectively analyzed. Tumor primary sites were summarized. Association between tumor site and pathological grading in gastroenteropancreatic neuroendocrine neoplasm(GEP-NEN) was examined.
RESULTSThere were a total of 903 cases of NEN. Sites of primary tumor included the digestive system in 699 cases(77.4%), the thorax(including lung, thymus and mediastinum) in 87 cases(9.6%), other sites in 60 cases (6.6%), unknown in 57 cases(6.3%). Among 699 GEP-NEN cases, the primary sites included the stomachin in 207 cases (29.6%), pancreas in 201 (28.8%), rectumin in 185 (26.5%), duodenum in 43(6.2%), jejunum and ileum in 18(2.6%), appendix in 15 (2.1%), gallbladder in 11(1.6%), esophagus in 10(1.4%), and the colon in 9 cases (1.3%). Pathologically, the tumor grading was neuroendocrine tumor (NET) G1 in 336 cases(48.1%), NET G2 in 203 cases (29.0%), neuroendocrine carcinoma (NEC) G3 in 139 cases (19.9%). All the esophagus NEN(10/10), most gallbladder NEN(9/11) and colon NEN(6/9) were poorly-differentiated NEC (G3), while all appendix NEN(15/15), most stomach NEN(147/207, 71.0%), pancreas NEN (156/201, 77.6%), rectum NEN (169/185, 91.4%), duodenum NEN (31/43, 72.1%), jejunum and ileum NEN(16/18, 88.9%) were well-differentiated NET G1 or G2.
CONCLUSIONSThe most common primary site of NEN is the digestive system. The stomach, pancreas and rectum are most common primary sitesof GEP-NEN. Difference in pathological grading is quite greatin different primary sites of GEP-NEN. Most NENs fromesophagus, colon and gallbladder are poorly-differentiated NEC.