1.Anti N-Methyl-D-Aspartate Receptor Encephalitis with Ovarian Teratoma: A Dilemma in Diagnosis
Lee CL ; Zainuddin AA ; Abdul Karim AK ; Yulianty A ; Law ZK ; Md.Isa N ; Nor Azlin MI
Journal of Surgical Academia 2016;6(1):66-69
We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old
woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation
revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result
showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-DAspartic
acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody
associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the
tumour and immunotherapy resulted in full recovery.
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
2.Congenital Peritoneal Band Causing Bowel Ischaemia Post Caesarean Section: A Rare Occurrence
Phon SE ; Ng BK ; Ng WYL ; Rahman RA ; Zainuddin AA ; Mahdy ZA
Journal of Surgical Academia 2017;7(2):28-31
Congenital peritoneal band is an extremely rare condition, but may induce small bowel obstruction (SBO) at any age,
predominantly in childhood and rarely in adults. We report a case of extensive bowel ischaemia following caesarean
section, due to trapping of an intestinal loop between a congenital peritoneal band and the mesentery. A 42-year-old,
Gravida 2 Para 1, who has no history of prior abdominal surgery or trauma, presented in spontaneous labour and
underwent an uncomplicated emergency lower segment caesarean section, for fetal distress. Postoperatively, she had
worsening abdominal distension and pain, followed by vomiting. Computed Tomography Scan of the abdomen
showed gross fluid retention with marked small bowel dilatation and fluid filled bowel loops. An emergency
exploratory laparotomy was performed which revealed a congenital band, extending between the right fimbrial end
and the small bowel mesentery, looping over the small bowel, causing extensive small bowel ischemia. Postoperative
course was uneventful. In conclusion, congenital peritoneal band causing small bowel obstruction,
although rare, should be considered in the differential, especially for patients with virgin abdomen.
3.THE PUBERTY PROFILE OF FEMALE ADOLESCENTS IN CHERAS, MALAYSIA
Zainuddin AA ; Siti Nazirah MS ; Lee MW ; Kamaruzaman SAR ; Goh KS ; Saiful Islam AH ; Hasan MT ; NurAzurah AG ; Fong AH ; Aiman H ; Anizah A
Journal of University of Malaya Medical Centre 2018;21(2):64-69
Objectives: The objectives of our study were to determine the mean age of onset of thelarche and menarche, to determine the ages of each stage of puberty and to investigate if there are any ethnic differences in these ages amongst female adolescents in Kuala Lumpur, Malaysia. Methods: This was a cross-sectional study involving three secondary schools in Cheras, Kuala Lumpur. A total of 730 students were recruited via stratified random sampling. Self-administered survey forms on menstruation and puberty were used. Results: Out of 730 recruited respondents, 385 (52.74%) completed the survey and informed consents were obtained from their parents/legal guardians. Our respondents’ ages ranged between 13 to 17 years old with the median (IQR) age of 14.00(2.00) years. With regards to ethnicity, 329 (85.50%) were Malay, 46 (11.90%) were Chinese, 9 (2.30%) were Indian and 1(0.30%) was a Bajau. The mean age for breast development (thelarche) and menarche were 11.72 ±1.10 and 11.97±1.11 years respectively. The majority, 363 (94.30%), out of 385 respondents had attained menarche. There appeared to be a later onset of puberty amongst Malays comparatively. Conclusion: The mean ages of pubertal onset and menarche amongst female adolescents in the Cheras area are similar to those reported worldwide.