Objective:To explore the diagnostic value of magnetic resonance(MR)high-resolution imaging of vascular wall on vertebrobasilar artery tortuosity prolongation complicated by multiple cerebral infarction in posterior circulation.Methods:Regression analysis was used in this research.A total of 138 patients with vertebrobasilar artery tortuosity prolongation who admitted to Hengshui City People′s Hospital from January 2020 to January 2023 were selected.Among of them,54 patients who complicated with multiple cerebral infarction in posterior circulation were divided into the occurrence group,and 84 patients without multiple cerebral infarction in posterior circulation were divided into the non-occurrence group.All patients underwent high-resolution MR imaging of vascular wall,and the basilar artery(BA),hemodynamic indicators such as systolic peak(Vs),average peak(Vd),diastolic peak flow velocity(Vm),pulsatile index(PI),blood flow resistance index(RI),as well as intracranial responsibility plaque characteristics and vertebral basilar artery grading between two groups were compared.Results:The Vs,Vd,Vm,PI and RI indicators of patients in the non-occurrence group were significantly higher than those in the occurrence group,and the differences were statistically significant(t=11.742,4.323,7.367,4.824,2.351,P<0.05),respectively.The degree(60.31±4.24)%of intracranial plaque stenosis in the non-occurrence group was significantly lower than(73.67±5.96)%in the occurrence group,and the difference was statistically significant(t=15.376,P<0.05).There were no statistically significant differences in plaque area,plaque load,arterial remodeling index and eccentricity index between the two groups(P>0.05).The height level of vertebral basilar artery bifurcation and the degree of vertebral basilar artery deviation in the non-occurrence group were significantly lower than those in the occurrence group,with statistically significant differences(x2=3.907,6.419,P<0.05).Conclusion:MR high-resolution imaging of vascular wall can clearly display the blood flow velocity and intracranial plaque situation in patients with vertebrobasilar artery tortuosity prolongation,and conduct the grade for the vertebrobasilar artery,which has significant application value in predicting the occurrence of vertebrobasilar artery tortuosity prolongation complicated by multiple cerebral infarction in posterior circulation.