Objective To explore the diagnostic value of multislice spiral CT enterography(MSCTE) in patients with primary tumors of the small intestine.Methods Clinical data of 40 patients with primary tumors of the small intestine from Jan.2011 to Dec.2013 were analyzed.All patients were underwent MSCTE examination.Analyzed the coincidence rate between diagnostic results and pathological diagnosis.Results Pathological diagnosis of all patients showed that 15 cases were with small intestinal stromal tumors,10 cases with primary intestinal adenocarcinoma,9 cases with intestinal lymphoma and 6 cases with leiomyoma.The diagnoses of MSCTE were as follows:Twelve cases were with gastro intestinalstromaltumors,10 cases with primary intestinal adenocarcinoma,9 cases with intestinal lymphoma and 9 cases with leiomyoma.Consistency test(Kappa test) results showed that there was a good consistency between two dignosis methods(Kappa values =0.71).The coincidence rate of MSCTE in the diagnosis of primary tumors of the small intestine was 92.5％.Conclusion MSCTE is a convenient and safe method with high degree of accuracy,which provides a broad prospect for the diagnosis of primary tumors of the small intestine.

Objective To investigate the imaging characteristics of primary abdominal cocoon in order to improve diagnosis level.Methods The imaging data of 5 cases of primary abdominal cocoon proved by surgery and pathology were retrospectively analyzed.Results Abdominal plain X-ray suggested intestinal obstruction in 3 out of 5 cases.The gastrointestinal barium meal showed cauliflower signal in all 5 cases;CT suggested a conglomeration of multiple small bowel loops in the 5 cases and the intestinal loops seemed to be encapsulated in a thickened capsule.Conclusion Abdominal cocoon should be taken into consideration when gastrointestinal barium meal shows cauli flower signal and CT displays conglomeration.

Objective To evaluate the effect of comprehensive intervention measures on preventing and controlling surgical site infection (SSI)in patients undergoing total abdominal hysterectomy.Methods Patients undergoing total abdominal hysterectomy in a hospital between January 2011 and December 2014 were investigated retrospec-tively,patients in 2011 were as control group,from January 2012,a prospective monitoring on SSI was initiated, comprehensive intervention measures were taken,patients between January 2012 and December 2014 were as inter-vention group,SSI before and after the intervention was compared.Results A total of 1 052 patients undergoing to-tal abdominal hysterectomy were investigated,267 cases were monitored before intervention,25 patients (9.36%) developed healthcare-associated infection (HAI),12(4.49%)of whom were with SSI;785 cases were monitored af-ter intervention,13 (1 .66%)of whom were with SSI,incidence of SSI in 2012,2013,and 2014 were 2.31 %, 1 .89%,and 0.77% respectively,there was a decreasing tendency(χ2 =7.30,P <0.01 ).Conclusion Prospective monitoring on SSI and comprehensive intervention can reduce the incidence of SSI in patients undergoing total abdominal hysterectomy.

Objective To investigate the clinical efficacy of gemcitabine and cisplatin chemotherapy combined with CT guided microwave ablation used in treatment of advanced squamous cell lung cancer. Methods 76 patients with lung squamous carcinoma in our hospital from April 2013 to July 2015 were selected,and randomly divided into treatment group and control group,38 cases in each groups. The control group were treated with gemcitabine and cisplatin chemotherapy. The patients in the treatment group in the control group based on the combined CT guided ablation under microwave, after the end of treatment to evaluate the efficacy of the two groups of patients, observe two groups of patients with adverse reactions, and were followed up for 1-2 years. Results The total effective rate of treatment group was significantly higher than the control group (P<0.05); pneumothorax treatment group after microwave ablation in patients with 2 cases, 3 cases of hemoptysis, 2 cases of fever, recovered after symptomatic treatment. The adverse reactions of the two groups due to chemotherapy caused by comparison of the rate of no significant difference; the treatment group of patients with PFS was significantly longer than the control group, the 1 year survival rate and 2 year survival rate was significantly higher than the control group(P<0.05). Conclusion Gemcitabine combined with cisplatin chemotherapy regimen combined with CT guided microwave ablation is effective in the treatment of advanced squamous cell lung cancer, and is worthy of clinical promotion.

Neovascularization is the main cause of blindness, such as diabetic retinopathy, retinopathy of prematurity and age - related macular degeneration. Vascular endothelial growth factor( VEGF) plays an important role in the formation of angiogenesis, and is considered to be the most potent angiogenic growth factor. Placental Growth Factor(PlGF) is one of the VEGF family, which play a crucial role in endothelial cell proliferation and migration, angiogenesis, and immune - mediated inflammation. Meanwhile, PlGF is specifically expressed in pathological angiogenesis, but not in normal blood vessels. In recent years, there has been increasing attention to PlGF, therefore this article reviews the role of PlGF in neovascular ocular diseases.

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OBJECTIVE To understand the status of hand hygiene and hand-washing compliance in grass-roots hospitals and investigate the relation between hand hygiene and hospital infections to institute the administration strategy of hand hygiene.METHODS Hand contamination of medical staff in grass-roots hospitals was investigated.The species carrying were detected and the reason was analyzed.RESULTS The carrying rate of pathogenic bacteria before hand-washing was 100.0% while that after hand-washing was 36.5%.The pathogenic bacteria carrying included: Staphylococcus aureus,Escherichia coli,Klebsiella pneumoniae,Proteus,Pseudomonas aeruginosa,P.alcaligenes,coagulase negative Staphylococcus,Enterococcus,etc.CONCLUSIONS The hand contamination is the important risk factor of cross infection.We should streng then hospital infections idea among medical staff,think highly of supervision of hand hygiene and enhance the recognition and compliance of hand-washing to eliminate effectively the cross infection transmitted through hands.

ObjectiveTo investigate the effect of bone marrow-derived mesenchymal stem cells (MSCs) on collagen-induced arthritis(CIA) and the possible mechanisms. MethodsMSCs from C57BL/6 mice bone marrow were isolated and expanded. Three DBA-I mice were as normal control group (Sodium Chloride injected on day 0 and 21) after primary immunization. After the bovine collagen Ⅱ induced-CIA models were established, fifteen male mice were randomly divided into 3 groups according to treatment regi-mens: CIA control group(0.2 ml Sodium Chloride injected through caudal vein on day 0 and 21), prevention group(1×10+6 cells MSC on day 0) and treatment group. (1×10+6 cells MSC on day 21 after primary immun-ization). The observed parameters included arthritis index (Al), articular pathology changes, levels of serum TNF-α, IL-1β detected hy ELISA. In addition, the percentage of CD4+CD25+Foxp3+Treg cells(Tregs) in CD4+ T cells of spleen or lymphoid node from mice were also analyzed by flow cytometry(FCM). Results①The Al and articular pathological score of the prevention group and treatment group were lower than the CIA control group(P<0.05). ②The levels of serum TNF-α and IL-1β of normal control, prevention group and treatment group were significantly decreased compared with CIA control group(P<0.05), and positively correlated with Al or articular pathological score (P<0.05). ③The percentage of Tregs from spleen and lymph nodes was significantly increased in MSCs treated mice(P<0.05). Conclusion MSCs transplantation is effective for CIA and suppression of TNF-α, IL-1β and up-regulation of Tregs by MSCs may be the possible mechanism in CIA.

Myasthenia gravis is an autoimmune disorder resulting from the production of antibodies against acetylcholine receptors leading to the destruction of the postsynaptic membrane at the neuromuscular junction.Myasthenic crisis is defined as any myasthenia gravis exacerbation necessitating mechanical ventila-tion or post-operation extubation delayed beyond 24 hours because of respiratory weakness.Most patients presenting with myasthenic crisis have an identifiable risk factor.The diagnosis of myasthenic crisis should be suspected in all patients with respiratory failure,particularly those with unclear etiology.Acute management of myasthenic crisis includes ventilatory therapy,removal of the offending trigger and immunomodulatory treat-ments.The latter includes plasma exchange or intravenous immunoglobulin,and high dose corticosteroids therapy.