China ; Drugs, Chinese Herbal ; standards ; Ethics, Medical ; Humans ; Medicine, Chinese Traditional

The current graduate student curriculum of medical colleges and universities has not been able to satisfy the actual need of cultivating the medical graduate students. In certain extent it stresses the natural sciences, theory curriculum and knowledge instruction more than humanities social sciences,technical curriculum, and cultivation of students' ability. Based on the reform of our curriculum setup, the author put forward some suggestions such as expanding the course resources, enriching the content,implementing the second-level management system, being clear about the different cultivation flow and the curriculum name; paying attention to staff construction and perfecting graduate student curriculum assessment and so on.

Discussions were made regarding the burden of persuasion and that of proof in tort lawsuits,distribution of the burden of persuasion in both medical tort cases and those in non-medical malpractice tort lawsuits.It is found that in cases involving tort of medical institutions,medical behavior tort and non-medical tort cases should be set apart depending on the nature of the lawsuit.Under the existing legal system,it is also necessary to distinguish the medical behavior tort incurred by medical malpractice from that irrelevant to malpractice.which will be critical for distribution of the burden proof and calculation of the compensation.

From the three aspects of university,family and the students themselves,the article points out that universities should transform the teaching thought and approaches and give the students poor in study the teaching guidance and humane care,parents should grasp the laxation of educating their children and students should pay attention to regulation and self-regulation.Only through the joint efforts,can the students walk out of study confusion to realize the healthy development

BACKGROUND:To delay the onset of Alzheimer’s disease, transplantation of viable and wel-differentiated stem cel s is expected to repair neural tissue, which has been an issue of concern. OBJECTIVE:To explore the effects of different doses of human umbilical cord mesenchymal stem cel s (hUCMSCs) on learning and memory ability of Alzheimer’s disease rats. METHODS:Fifty Sprague-Dawley rats, 7 months of age, were randomized into normal, model, high-, middle-and low-dose hUCMSCs groups (n=10 per group). Rats in model and UCMSCs groups were used to make Alzheimer’s disease animals through intraperitoneal injection of 150 mg/kg D-galactose for 90 days, and rats in the normal group were given intraperitoneal injection of normal saline for 90 days. In the three hUCMSCs group, passage 3 hUCMSCs at doses of 1×105/0.2 mL/20 g, 5×105/0.2 mL/20 g, and 1×106/0.2 mL/20 g were injected via the tail vein, respectively. Forty-five days after cel transplantation, Morris water maze test was used to detect rat’s learning and memory abilities, and hematoxylin-eosin staining was used to observe pathological changes of the rat hippocampal CA1 region. RESULTS AND CONCLUSION:Compared with the normal group, the rats in the model group showed significant reduction in the ability of learning and memory. Compared with the model group, the escape latency was significantly shortened in the middle-dose hUCMSCs group (P<0.05), while the number of passing times through the platform was increased significantly (P<0.05). In the model group, the cel s in the hippocampal CA1 region were arranged irregularly with unclear nucleoli and a part of cel s were concentrated and deeply stained. In the middle-dose hUCMSCs group, the cel s in the hippocampal CA1 region were arranged regularly with clear nucleoli, and only individual cel s were stained deeply. These findings indicate that middle-dose hUCMSCs transplantation can improve the learning and memory abilities of Alzheimer’s rats.

Fluorescence in situ hybridization (FISH) is a non-radioactive technique by use of fluorescently labeled DNA probes in detecting chromosomal alterations in cells. As a new molecular cytological method, it can detect various types of cytogenetic alterations, including deletion, amplification and translocation, as well as improve the accuracy of pathological diagnosis if combined with histomorphology. This review focuses on the application of FISH to the detection of some solid tumors.

Taking the application of integration teaching in neurology curriculum as an example, by analyzing the Harvard Medical School , the University of Toronto School of Medicine and the Shanghai Jiaotong University School of Medicine on the course curriculum, the issues related to neurology curriculum integration has been explored. The results show that the integration of teaching mode reflects the two major characteristics of multi discipline integration, clinical and basic integration, and it emphasizes the organ system as the center, the problem based learning (problem-based learning, PBL), Problem-Based Learn-ing, Case-based Learning and other teaching methods will play an important role in the medical educa-tion reform in the important position.

Objective: To analyze the Effect of isokinetic training on knee injury patients’ recovery function. Methods: Choose knee injury patients between October 2012 to October 2013 as research object, randomly divided into control group received conventional training, and observe group received isokinetic training, each with 49 cases, detecting knee function after training, stretching flexor muscle strength, range of motion. Results: 1) After training ,both groups of patients inflammation Lysholm knee function scores were higher than before,and observation group patients Lysholm knee function score were significantly higher; 2)After training, both groups extensor flexor muscle strength were higher than before,and the observation group patients’ stretched flexor PT, AP, MRTW level were higher; 3)After eight weeks of training and 16 weeks, observation group patients’ knee extension, knee flexion angles were significantly higher.Conclusion:Isokinetic exercise training can improve knee joint function in patients, improve muscle strength while expanding its range of motion, improve the quality of life of patients.

Neovascularization is the main cause of blindness, such as diabetic retinopathy, retinopathy of prematurity and age - related macular degeneration. Vascular endothelial growth factor( VEGF) plays an important role in the formation of angiogenesis, and is considered to be the most potent angiogenic growth factor. Placental Growth Factor(PlGF) is one of the VEGF family, which play a crucial role in endothelial cell proliferation and migration, angiogenesis, and immune - mediated inflammation. Meanwhile, PlGF is specifically expressed in pathological angiogenesis, but not in normal blood vessels. In recent years, there has been increasing attention to PlGF, therefore this article reviews the role of PlGF in neovascular ocular diseases.

Objective:To evaluate the efficacy and safety of controlled-release dinoprostone pessary(propess) in cervical ripening and intermediate labor induction.Methods:Eighty primiparas with uterogestation and Bishop score ≤6 points and no vaginal delivery taboo were equally divided into a study and a control group.The former received intravaginal administration of propess and the latter intravenous injection of low-dose oxytocin by the randomized control method.Comparisons were made of the Bishop score,delivery and the state of the fetuses and neonates between the two groups.The side effects of propess were observed.Results:Bishop scores were 7.75?2.227 and 6.38?2.862 in the study and the control group respectively 12 hours after the medication,significantly higher than 4.23?1.025 and 4.15?1.099 before the induction(P 0.05).The major side effect of propess was the over-frequent and over-strong contraction of the uterine,which occurred in 2 cases in the study group but subsided after its removal.Conclusion:Dinoprostone pessary,effective,safe and convenient,is obviously superior to oxytocin in cervical ripening and labor induction.