1.The risk factors analysis of patients with hemorrhagic stroke in Zhongshan district of Dalian city
Clinical Medicine of China 2014;30(4):389-391
Objective To explore the risk factors analysis of patients with hemorrhagic stroke in Zhongshan district of Dalian city in order to providing the Corresponding intervention measures.Methods From Oct 2010 to Aug 2013,183 cases of patients with hemorrhagic stroke(age > 60 years old) and 158 cases healthy physical people in Zhongshan Hospital Affiliated to Dalian University were served as observation group and control group.Clinical information and life habit of two groups were recorded,the height and weight were measured,body mess index (BMI) was calculated,blood lipid level and plasma fiber protein level were detected.Results The rate of male,age >70 years,BMI index ≥25 kg/m2,smoking,history of hypertension,TG ≥ 1.7 mmol/L,TC ≥ 5.7 mmol/L,fibrinogen < 4.0 g/L in observation group were 68.85 % (126/183),65.03% (119/183),61.75% (113/183),77.05% (141/183),32.24% (59/183),51.37% (94/183),62.30% (114/183),68.31% (125/183) respectively,higher than those of control group (51.90% (82/158),44.94% (71/158),39.87% (63/158),17.72% (28/158),18.99% (30/158),29.11% (46/158),36.08% (57/158),82.91% (131/158),the differences were statistically significant (x2 =8.725,27.167,12.742,95.064,5.825,14.056,18.478,7.314,P < 0.05).However,there were no significant differences in terms of diabetes history,drinking,high density lipoprotein-cholesterol level and low density lipoprotein-cholesterol between two groups.Conclusion Hemorrhagic stroke is closely related to many factors.Sex,age > 70 years,smoking,obesity,history of hypertension,high cholesterin (TC ≥ 5.7 mmol/L) are independent risk factors of patients with hemorrhagic stroke in elderly.Through the control target population's blood pressure and blood lipids,rational diet,appropriate exercise,quit smoking and alcohol,adjust the good point of view,we can prevent the occurrence old hemorrhagic stroke.
2.Preventive and Therapeutic Effect of Weitong Injection on Postoperative Intestinal Adhesion of Rats
China Pharmacy 2005;0(21):-
OBJECTIVE: To study the preventive and therapeutic effect of Weitong injection(WTI) on the postoperative intestinal adhesion of rats.METHODS: Forty SD rats were randomly divided into five groups: blank control group,model control group,Dexamethasone group and high-dose WTI group and low-dose WTI group.Postoperative intestinal adhesion model was established in all the rats except those in the blank control group.On the operative day,the blank control group and the model control group received Normal saline(1 mL?kg-1);the Dexamethasone group received Dexamethasone(5 mg?kg-1),and WTI group received WTI(4 mg?kg-1 and 2 mg?kg-1,respectively) all via vena caudalis for 7 consecutive days.On day 8,laparotomy was performed on the rats for the evaluation of the degree of intestinal adhesion and the tissue of cecum was collected for the determination of the content of hydroxyproline(Hyp) and the pathological section test.RESULTS: The degree of postoperative intestinal adhesion of rats was attenuated by WTI(either high dose or low dose) or Dexamethasone.Furthermore,WTI significantly reduced the Hyp concentration in cecum tissue of rats with intestinal adhesion(P
3.Application of literature retrieval teaching in guiding reading of medical students in fragmentation era
Chinese Journal of Medical Library and Information Science 2014;(8):63-65
After the reading behaviors ( reading altitude, reading frequency, reading habits and reading types) of 141 students in medical school were investigated and analyzed, the efficiencies of literature retrieval teaching in classroom were summarized, and the future direction was proposed.
4.Recognizing Ventricular Tachycardia and Fibrillation with Hurst Index
Space Medicine & Medical Engineering 2008;21(6):455-460
Objective To recognize normal sinus rhythm (NSR), ventricular tachycardia (VT) and ventricular fibrillation (VF) from each other accurately and promptly. Methods A nonlinear descriptor based on multi-scale analysis, Hurst index, as a feature to quantify the nonlinear dynamics behavior of the ECG signal, was quoted in this paper. Results The nonlinear technique, Hurst index was examined and evaluated with ECG signals extracted from MIT-BIH Arrhythmia Database, MIT-BIH Malignant Ventricular Ectopy Database, and CU Ventricular Tachyarrhythmia Database under a specific moving-window length. The experiment showed good performance of this nonlinear descriptor. When the window length was 5 s long, the recognition accuracy for each of NSR, VT and VF was 100%. Besides, the computing speed was much faster than the speed obtained with a traditional non-linear technique, the complexity measure algorithm. Conclusion The Hurst index has a strong potential for life-threatening ventricular arrhythmia recognition in clinical applications.
5.Application of Tracer Methodology in Reducing Dispensing Errors in PIVAS
China Pharmacy 2015;(25):3525-3527
OBJECTIVE:To reduce dispensing errors in Pharmacy intravenous admixture service(PIVAS),improve compound-ing quality of transfusion and guarantee the safety and rationality of clinic transfusion. METHODS:The case tracking method was applied to analyze each link of the work in PIVAS to find the reasons of configuration errors and control risk;and then the system tracking method was applied to analyze the hidden safety risk and the crack of quality from the inside of the system and work flow. Countermeasures and supporting continuous improvement were established to evaluate the effect of management before and after 6 months. RESULTS:Tracer methodology(TM)was adopted to find out the weakness in the key link and work flow of the cause of the configuration errors,the relative work pattern and work environment was improved,the relative system was formulated and completed,strength of rewards and punishment was increased. Through the implementation of the countermeasures,the number of dispensing errors was reduced from 81 to 38,and the error rate was reduced from 0.035% to 0.011%(P<0.01). CONCLU-SIONS:TM can be adopted in the key link and work flow of the cause of the configuration errors,aim at formulate and strictly carry out relative countermeasures to reduce errors in PIVAS,and promote the safety of drug use.
7.Immunization in children with kidney diseases.
Chinese Journal of Pediatrics 2007;45(4):318-320
8.Application and progress of surgical nutrition
Chinese Journal of General Surgery 2001;0(08):-
Nutrition support is extensively used in many clinical fields. The rest energy requirement in Chinese is only 5021~5858kJ/d.In our country 40% to 50% of hospitalized patients need nutrition support.In nutrition support,attention should be paied to :(1)The energy giving to the patient should be appropriate;(2)hormone resistance;(3)immunonut rition.
9.Clincial Observation on the Efficacy of Methylprednisolone Stosstherapy of IgA Nephropathy Complicated With Partial Crescenties Formation
Journal of Chinese Physician 2001;0(03):-
Objective To observe the efficacy of methylprednisolone stosstherapy of the IgA nephropathy complicated with partial crescenties formation and effects of this therapy on the urine protein output and renal function.Methods 93 patients of IgA nephropathy complicated with partial crescenties formation were identified by renal biopsy and diagnosed according to the WHO diagnostic criteria in 1982 formulation.The patients were randomly divided into two groups:the control and the treating groups.The control group was treated with oral prednisolone (1mg/Kg/day) plus oral cyclophosphamide(2mg?kg -1 ?d -1 ),while the treating group was administered, on the basis of the therapeutic scheme of the control group,with methylprednisolone 0 5~1 0g(20mg?Kg -1 ?d -1 ) in normal saline solution intravenously by drip,for 8 weeks,The degree of puffiness,BP and 24h urine volume were observed in both groups befoue and after the treatment. The 24h urine protein quantitative determination,urine RBC count(uRBC),urine creatinine,blood creatinine(Cr),blood urea nitrogen(BUN),serum albumin (ALB) and the endogenous creatinine clearance rate (Ccr) were also tested.The side effects in two groups were observed at the same time.Results The urine protein output amounts, urine RBC count,blood Cr and BUN were significantly decreased (P