1.Amending and evaluation of body dysmorphic disorder questionnaire
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(5):466-467
Objective To evaluate the reliability and validity of body dysmorphic disorder questionnaire (BDDQ) Chinese version. Methods A total of 222 participants from a plastic surgery department were enrolled in the study by systematic sampling. They were measured with BDDQ Chinese version and interviewed with Structured Clinical Interview for DSM-]V-TR-Patients( SCID/P) to evaluate the validity. Fifty participants were assessed again after two weeks to evaluate the test-retest reliability. Results The sensitivity of BDDQ Chinese version was 100% and the specificity was 93%. The correlation coefficient of each item was between 0. 808 and 1.000(P< 0.001). Conclusion BDDQ Chinese version has fairly high reliability and validity. Thus, it can be used as a screening diagnosis tool for BDD.
2.Layered target for evaluating axial resolution of very-high-frequency B-type ultrasonoscope
Chinese Medical Equipment Journal 1989;0(03):-
A novel layered target is designed to evaluating the axial resolution of very -high -frequency B -type ultrasonoscope. Compared with the conventional target made of tungsten wire, the target proves to be accurate, reliable and easy to make and to use, and thus it is a potential gauge or a test tool.
3.The Importants of Insistence on The principle of Informed Consent in Operation Therapy
Chinese Medical Ethics 1995;0(02):-
The informed consent is the principle of medical ethics with which all the doctors in hospital should consistently comply in their medical therapy. Particularly in operation therapy, it is so important for doctors to insist on this medical ethics principle which embodies the specific principle for patients' dectisions for themselves. This accords with the general norm of medical ethics that patients are respected by the hospital. This principle is the morality requirement for operation therapy, and also one of the important measures for effectively reducing and avoiding medical disputes.
4.Influencing Factors for Effect of Ozone in Drinking Water Disinfection
Journal of Environment and Health 1992;0(05):-
Objective To assess the role of various factors in the sterilization effect of ozone in water and provide the basic data for the correct use of ozone generator. Methods E.coli 8099 was employed as the indicative bacteria. The effect of killing E.coli 8099 by ozone in water was detected under various conditions,such as temperature,pH value,flux. Results The inactivated rates of indicative bacteria were 99.99%~100% by ozone in five minutes under the basic condition of 20 ℃,pH=7.0 and ozone flow of 1 L/min. The bactericidal effect was relatively better at low temperature and low pH value,the high flow of ozone led low sterilization effect of ozone. Conclusion High temperature,higher pH value,higher flow is not conducive for ozone to be dissolved in water,thereby will affect the bactericidal effects of ozone.
5.The (CCTTT)n microsatellite polymorphism of NOS2 gene in Han nationality in the southwest of China
Journal of Chongqing Medical University 2003;0(05):-
Objective:To investigate genotypes and alleles' distributions of inducible nitric oxide synthase (NOS2) gene (CCTTT)n polymorphism in Han nationality in the southwest of China,and make comparisons with different race or the same race in different areas.Methods:The (CCTTT)n polymorphisms of NOS2 gene were analyzed in a total of 205 southwestern Chinese healthy subjects by polymerase chain reaction (PCR)-8% denature polyacrylamide gel electrophoresis(PAGE)-silver staining and DNA sequencing.Results:(1)Nine alleles and thirty genotypes were identified.(2)(CCTTT) 9,(CCTTT) 10 ,(CCTTT) 12 ,(CCTTT) 13 alleles frequencies of NOS2 gene in Chinese Han population in southwestern area differed significantly from those in northern area.(3)(CCTTT) 9,(CCTTT) 10 ,(CCTTT) 11 ,(CCTTT) 15 ,(CCTTT) 16 alleles frequencies of NOS2 gene in Han population of the southwest of China differed significantly from those of Caucasians in England.Conclusion:The (CCTTT)n microsatellite polymorphisms of NOS2 gene are different not only among different ethnic populations but also within the same population of different areas, which may be of significance in the studies on relationship between genetics and disease.
6.Mechanism and clinical application of spontaneous retinal venous pulsations
Chinese Journal of Experimental Ophthalmology 2012;(11):1048-1051
Spontaneous retinal venous pulsations(SVPs) appears in 90% of normal persons.It is seen as a rhythmic subtle narrow and expansion of one or more retinal veins on the optic disc.Many researches have demonstrated that SVPs could be applied to the intracranial pressure(ICP) monitoring as well as diagnoses and fellow up of glaucoma.But there is no corresponding domestic research in this field up to now.Although the physiological mechanism of the venous pulsations has been the point of much debate,its potential clinical value attract our attention.The present paper reviewed the progress in current understanding of the mechanism behind the SVPs,the examination method and application of SVPs in clinical study.
7.A research on the method of axillary osmidrosis treatment using minimally invasive resection of apocrine sweat gland and thick skin flap in armpit wrinkle
Chinese Journal of Postgraduates of Medicine 2012;35(8):13-15
ObjectiveTo study the curative effect of axillary osmidrosis,that incision in armpit wrinkle,orthoptic cut off the gland to thick skin flap.MethodsCollected double-sided axillary osmidrosis 163 patients,all of them accepted armpit wrinkle incision,the scope of surgical operation super the armpit hair distribute 1 cm,swelling anaesthesia,orthoptic cut off the armpit organization 5 mm under skin included apocrine sweat gland,kept the operation scope to vessel net flap under skin.Hematischesis thoroughly used a double pole electricity hemostasis,kept drainage after operation,bandaged in pressure,took out sutures after 9 days.The foul smell standard referenced the Tung-Chain standard of axillary osmidrosis curative effect evaluation.ResultsThree hundred and twenty armpits (98.16%,320/326) were cure,6 armpits (1.84%,6/326) were excellence.The armpit hair variety:obvious reduce 322 armpits(98.77%,322/326),general reduce 4 armpits(1.23%,4/326).Perspire condition:obvious reduce 324 armpits(99.39%,324/326),improve but no obvious reduce 2 armpits ( 0.61%,2/326).The average surgical operation recovery time was about 9 days.Complication:necrosis on the edge of the skin was 8 armpits,scar formation on the incision was 3 armpits,hematoma was 1 armpit,shoulder joint limitation of activity was 0 armpit.ConclusionThe method of axillary osmidrosis treatment useing thick skin flap in armpit wrinkle,which has extermination foundation of anatomy and pathology,which can cause axillary osmidrosis,this operation is simple,curative effect is credible,the wound is small,complication is little etc,utmost matching the principle of orthopedic surgery,worthy of clinical application.
8.Application of modified minimally-invasive transverse-vertical epicanthoplasty in double-eyelid plastic with three points at the same period
Chinese Journal of Primary Medicine and Pharmacy 2012;19(10):1447-1448
ObjectiveTo assess the effect of modified minimally-invasive transverse-vertical epicanthoplasty in double-eyelid plastic with three points at the same period.Methods87 cases with mild or moderate epicanthus and oriental eyelid were involved in our research.Epicanthoplasty was performed based on the principle of transversevertical plasty.The curvilinear incision of epicanthoplasty was made between the desired point of the new medial canthus and the lower lacrimal point,the malpositioned orbicularis oculi muscle excised after skin undermining,the superficial head of the medial canthal tendon plicated or anchored to the lateral nasal aponeurosis and the incision closed after skin redraping.Double-eyelid plastic with three points was performed as usual,however,the incision of eyelid plastic was connected with the incision of epicanthoplasty by skin tunnel in which a strip of orbicularis oculi muscle was excised.Results87 cases were followed-up for 3 to 24 months.The cosmetic results of the new medial canthi were satisfactory with new figure and inconspicuous scar.The contours of the double eyelids were natural.No incisional scar presented between the medial canthi and the upper eyelids.No recurrence of epicanthus was observed.ConclusionThe modified mini-incisional transverse-vertical epicanthoplasty together with double-eyelid plastic with three points is a simple and effective feasible surgical approach for correction of epicanthus and oriental eyelid.
9.Effect of mycophenolate mofetil on vascular structure and cytokines and receptors of rat with pulmonary arterial hypertension
Chinese Journal of Rheumatology 2011;15(9):625-628
ObjectiveTo observe the effect of mycophenolate mofetil(MMF) on systolic pulmonary arterial pressure (SPAP), right ventricle index (RVI), cytokines, receptors of pulmonary artery hypertension (PAH) rat models. MethodsThe rat models of monocrotaline (MCT)-PAH were developed. Thinty-two Sprague-Dawley male rats were divided randomly into four groups: the control group, the MCT, the MCT +low-dose MMF (20 mg·kg-1·d-1, MMF 20) and the MCT + high-dose MMF(40 mg·kg-1·d-1, MMF 40).There were eight rats in each group. SPAP, RVI, cytokines and receptor in the serum and lung tissue were measured in all rats. Comparisons between multiple groups were performed with q test and rank sum test.Results① Low-dose and high-dose MMF group were compared with the MCT group, SPAP[(40±13),(53±10) vs (68±10) mm Hg]and RVI(0.36±0.06, 0.38±0.03 vs 0.44±0.05) were reduced and showed statistically significant difference respectively(P<0.05). (②) Compared with the MCT group, basic fibroblast growth factor(bFGF) of serum in both low-dose and high-dose MMF group were reduced and showed statistical difference respectively[(2.3±1.9), (2.7:t±1.3) vs (6.9±5.4) pg/ml, P<0.05]. ③ Low-dose and high-dose MMF group were compared with the MCT group and showed that MA was decreased and the musculization of arterial wall was improved. ConclusionMMF can reduce SASP, RVI, number of MA. The inhibitory effect of MMF in PAH is possibly by inhibiting cytokines and receptors.
10.Serum 25-hydroxyvitamin D and anti-vita min D status in new cases of systemic lupus erythematosus patients and their clinical significance
Chinese Journal of Rheumatology 2012;16(10):661-664
Objective The aim of this study was to detect the serum 25-hydroxyvitamin D (25-OH-D)and anti-vitamin D levels in new cases of systemic lupus erythematosus (SLE),and to investigate their clinical significance.Methods Fifty patients who fulfilled the ACR criteria for the classification of SLE and 36 healthy donors were included.Enzyme-linked immunosorbent assay was performed for serum 25 [OH] D and anti-vitamin D level measurement.Statistical methods used were t-test and Pearson's correalation analysis.Results The serum 25-OH-D level in SLE was (13±6) ng/ml,and the level in healthy donors wase (17±8)ng/ml,P =0.007); the difference was statistically significant.A significant negative correlation was demonstrated between the serum level of vitamin D and the 24 h urinary protein excretion (r=-0.314,P<0.01),and the level of serum creatinine (r=-0.322,P<0.01).Anti-vitamin D antibody was detected in 6 of 50 patients with SLE,in 10 of 36 sera from healthy donors.There was no difference of 25-OH-D level between the anti-vitamin D antibody positive group and anti-vitamin D antibodu negative group [(13±6) and (14±6) ng/ml in the SLE group; (17±6) and (18±9) ng/ml in the healthy control group].Conclusion The serum 25-OH-D level in SLE is low; however,it is not correlated with Anti-vitamin D antibody,but is correlated with renal lesions.So the serum 25-OH-D level may be important in the pathogenesis of SLE.