1.Surface Enhanced Raman Scattering Analysis on Safflower Injections
China Pharmacist 2015;(5):759-760,761
Objective:To study the surface enhanced Raman scattering ( SERS) of safflower and identify safflower injections by SERS quickly and effectively. Methods:Through comparative analysis of the Raman spectroscopy of safflower injections and the corre-sponding control herbs, the rapid identification of safflower injections was realized. Results:The results showed that several character-istic peaks of safflower were enhanced obviously in SERS, which could be used to identify safflower injections. Conclusion:The meth-od is reliable, rapid, accurate and specific, which can be applied as a method to identify safflower and its injections.
2.The development of military acute stress scale
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(7):658-661
ObjectiveTo develop the military acute stress scale and examine the reliability and validity of this scale.MethodsBased upon the previous acute stress researches and the rule of psychometrics,the military acute stress scale was compiled according to open-ended inventory survey.A total of 630 personnel were chosen by random cluster sampling,and tested with this scale,50 of them were tested by Chinese Military psychosomatic health Scale simultaneously,and 50 of them were retested after two week.The reliability and validity were examined by exploratory factor analysis,confirmatory factor analysis and correlation analysis.ResultsThe military acute stress scale was comprised of 9 factors and one lie sub-scale ; Main fit indexes of model were the following CMIN =1219.476,DF =593,P =0.000,CMIN/DF =2.056,IFI =0.927,TLI =0.902,CFI =0.924,RMSEA =0.059; The conrelation coefficients between subscales and subscales were 0.284-0.572.The correlation coefficients between subscales and total scale were 0.700 ~ 0.846 (P < 0.05 or 0.01 ) ; The correlation coefficients was significant between this scale and Chinese military psychosomatic health scale.The correlation coefficients were 0.338-0.962 (P < 0.01 ).The test-retest correlation coefficients of total scale and subscales were 0.379-0.909 (P < 0.01 ).The Cronbaeh's α coefficients were 0.606-0.926 ; and the split-half correlation coefficients were 0.466-0.855.ConclusionThe military acute stress scale has acceptable psychometrics properties on reliability and validity.
3.Clinical laboratory tests of venous thromboembolism in obstetrics and gynecology
Chinese Journal of Laboratory Medicine 2017;40(3):149-151
Venous thrombotic disease is a serious disease,which impact on health and life-threatening.Pulmonary embolism and deep-vein thrombosis are the two components of a single disease called venous thromboembolism in obstetrics and gynecology.but it can be difficult to diagnose because clinical symptoms and signs are non-specific or absent in early venous thrombus embolism (VTE).It has great value that how to use the most economic,simple,efficient method for screened high-risk groups,timely and accurate laboratory diagnosis of VTE.
4.Cost-effectiveness Analysis of Three Kinds of Statins for the Treatment of Hyperlipoidemia
China Pharmacy 2001;0(08):-
AIM:To evaluate the economic effectiveness in the treatment of hyperlipoidemia with three kinds of statinsMET_HODS:Using pharmacoeconomical cost-effectiveness analysis,simvastatin,fluvastatin and pravastatin in the treatment of 215 cases of hyperlipoidemia were comparedRESULTS:Fluvastatin was the best kind of statins in lasting treatment for hyperlipoidemiaCONCLUSION:The results show that pharmacoeconomics plays an important role in guiding rational drug use and increasing economic effectiveness
5.Effects of electro-acupuncture combined with hyperbaric oxygen on cognitive ability and plasma homocysteine in patients with dementia after cerebral infarction
Chinese Journal of Primary Medicine and Pharmacy 2013;20(21):3223-3225
Objective To explore the influence of electro-acupuncture combined with hyperbaric oxygen on cognitive ability and plasma homocysteine(Hcy) in patients with dementia after cerebral infarction.Methods 68 patients with dementia after cerebral infarction were randomly divided into the control group (34 cases) and the observation group(34 cases).The patients in the control group were treated through conventional treatment,and the patients in the observation group were treated through electric stimulation plus hyperbaric oxygen,one time every day,15 times was a course of treatment.The intelligence was evaluated and the level of Hcy was detected after treatment.Results Before treatment,the MMSE score and the plasma Hcy level of the observation group was (19.01 ±6.92) points,(26.84 ± 9.06) μmol/L,respectively,those of the control group was (18.76 ± 6.71) points,(26.14 ±8.79) μmol/L,respectively.After treatment,the MMSE score and the plasma Hcy level of the observation group was (25.77 ± 8.21) points,(15.15 ± 5.24) μmol/L,respectively,those of the control group was (20.18 ± 7.52) points,(21.32 ± 6.53) μmol/L,respectively.After treatment,the MMSE score of the observation group was significantly increased (t =3.6710,P < 0.05),and there was no significant change in the control group (t =0.5472,P > 0.05).The plasma Hcy level was significantly reduced after treatment in both two groups (t =2.0345,P < 0.01,t =2.5667,P <0.05),and that in the observation group was siginificantly lower than the control group (t =4.2970,P < 0.05).Conclusion Electric stimulation combined with hyperbaric oxygen can improve cognitive ability and decrease plasma Hcy level in patients with dementia after cerebral infarction.
6.Creation and maintenance of ORACLE standby database
Chinese Medical Equipment Journal 2004;0(08):-
As an available fault-tolerant technique of ORACLE,standby database can be used to perform disaster recovery.This article describes how to create and maintain an ORACLE standby database,and provides the solutions of common problems.
7.The opportunity and the manner of delivery in female with intrahepatic cholestasis of pregnancy
Journal of Chongqing Medical University 1986;0(03):-
Objective:To explore the opportunity and the manner of termination of pregnancy.Methods:The data of 200 cases of ICPfrom January 2007 to June 2008 were retrospectively analyzed.Maternal pruritis,liver function ,glycocholic acid(CG),amniotic fluid condition, the time and the way of termination of pregnancy,Apgar score were examined.Three groups were classified by the values of CG:Group A (CG
8.The effects of radix astragali on hypertrophic scars in rabbit ears
Journal of Chongqing Medical University 2003;0(06):-
Objective:To observe the effects of radix astragali on hypertrophic scars in rabbit ears. Methods:Twenty healthy adult Japanese big ear rabbits were given hypertrophic scars over the ventral surface of the ears and on the 21st day after wound,animals were randomly divided into the treated groups (groups A,B,and C were treated with radix astragali in different concentrations)and the control groups(groups D and E were treated with saline and blank control,respectively). On the 32nd and 43rd day after wound,the thickness and hardness of scar were measured.The TGF-?1mRNA were detected in hypertrophic scar samples with RT- PCR.The change of scar tissues was observed with H&E staining and immunohistochemical staining with TGF-?1. Results:The thickness and hardness of scar were inversely correlated with the concentration of radix astragali in the radix astragali-treated group(P0.05)between the 32nd day and43rd day groups.Conclusion:Radix astragali could inhibit proliferation of hypertrophic scars in the rabbit ears by decreasing the expression of TGF-?1mRNA and its protein. Thereby radix astragali may have beneficial effects in the treatment of hypertrophic scar.
9.Compared study of hematopoietic recovery of angelica polysaccharides dosaged pre-irradiation and post irradiation on radiation injured mice
Journal of Chongqing Medical University 2007;0(07):-
0.05).Conclusion:The results support our hypothesis that APS can be used to treat the hematopoietic type of acute radiation sickness.APS pretreated groups had better results than APS treated groups in initial observation.
10.Effect of Fructus Ligustri Lucidi on calcium metabolism and vitamin D-dependent gene expressions in ovariectomized rats
Chinese Traditional and Herbal Drugs 1994;0(04):-
Objective To investigate the effect of Fructus Ligustri Lucidi(FLL),a kidney-tonifying Chinese herbal medicine,on calcium metabolism and vitamin D-dependent gene expression in ovariectomized(OVX) rats.Methods Four weeks after OVX surgical operation the OVX rats were ig admini-(stered) with estradiol and FLL for 14 weeks.Ca~(2+) Level in serum,urine,and feces was measured by colorimetric methods,and gene expressions in duodenum and kidney were analyzed by reversed transcriptase-polymerase chain reaction(RT-PCR).Results Ovariectomy of rat led to significant loss of calcium in vivo,as demonstrated by decreasing serum Ca~(2+) level and increasing Ca~(2+) excretion rate in urine and feces in OVX rat group.Treatment of OVX rats with FLL could effectively restore serum Ca~(2+) level and prevent the increase of Ca~(2+) excretion from urine and feces.RT-PCR Analysis showed that both estradiol and FLL could prevent OVX-induced decrease of mRNA expression in duodenal vitamin D receptor(VDR).In kidney,FLL did not alter mRNA expressions of 25-hydroxyvitamin D 1-hydroxylase(1-OHase) and 25-hydroxyvitamin D 24-hydroxylase(24-OHase),while increased the mRNA expression levels of renal cal-ciumbinding protein-9k(CaBP-9k) and calcium-binding protein-28k(CaBP-28k).Conclusion FLL could improve the state of calcium imbalance induced by estrogen deficiency and the potential mechanism that contributes to the improvement of calcium status by FLL might involve the increase in intestinal sensitivity to active vitamin D through its up-regulation of VDR expression in duodenum and the enhancement in Ca~(2+) reabsorption via the up-regulation of calcium binding proteins expression in kidney.