Fatigue is one of the most common complaints in cancer patients that profoundly affects all aspects of quality of life.However,cancer-related fatigue remains under recognized and poorly treated.This rcview has been conducted with the causes and potential treatments of fatigue in cancer patients.The methods for evaluating fatigue,and possible therapeutic options are also discussed.

Children with plastic bronchitis,characterized by unknown origin,insidious onset,rapid progress,severe symptom and high mortality,is a relatively rare disease.Also,it is difficult to diagnose and treat with plastic bronchitis characterized by marked airway obstruction,via the formation of large gelatinous or rigid airway cast.It is associated with certain diseases including bronchial asthma,cystic fibrosis,accompanied with acute chest syndrome with sickle cell disease,congenital heart disease and bacterial and viral respiratory infection.Clinicians should be aware of this disease,and early bronchoscopy should be intervened.

Retinal ischemia-reperfusion injury (RIRI) is a common pathological and physiological clinical oculopathy,which can occur in retinal artery and vein occlusion,diabetic retinopathy and acute angle-closure glaucoma.The resulting ischemia can cause cell metabolic dysfunction,serious retinal damage and descending visual function.RIRI is the result of multiple factors.The currently accepted hypotheses mainly include the injury effect of oxygen-derived free radicals,intracellular calcium overload,the action of leucocyte and apoptosis.However the protection and treatment research in the RIRI is limited.The present paper reviews the progression in the drug intervention of RIRI.

Objective To design a new pre-treatment device and to evaluate its efficiency in order to monitor the tritium levels in biological samples.Methods The detection efficiency of tritium was determined with standard tritiated water.Recovery of tritiated water and organically bound tritium (OBT) were detected with high, medium and low activities of standard tritiated water and 3H-TdR (tritiated thymidine), respectively.Comparison of three kinds of biological samples using different pre-treatment devices was shown.Results The standard curve can be used in environmental tritium measurement and the detection efficiency for tritium was 23.3%.When 40.0 g rice with standard HTO or 3H-TdR was pretreated with this device, the average recovery of HTO and OBT was about 95.4% , which showed good reproducibility.The comparison results were similar.Conclusions The pre-treatment device can be used to survey the OBT in environmental biological samples.

The response of rat mesenteric microvessels to noradrenaline (NA) in different stages of endotoxic shock was investigated by using vital microscope with video television recorder. It was found that the diameter of the microvessels showed a dose-dependent decrease to local NA application from the low to high concentration. The constricted response curve was remained unchanged at the experimental duration. The constricted response to NA was increased significantly at early stage of shock but was decreased at late stage (both P

Objective: To investigate relationships among Cognitive performance,cognitive styles and Neuroticism.Methods: Experimental cognitive tests were administered to 30 Highly and 30 Lowly neurotic individuals under tightened and relaxed cognitive conditions.Results: Highly and Lowly neurotic individuals did not appear any differences in total scores,but significant differences in scores of tightened-relaxed cognitive styles.Highly Neurotic individuals mostly tend to be relaxed cognitive style,and Lowly Neurotic individuals to be tightened cognitive style.Conclusion: Neuroticism does not relate with total scores of cognitive performance under tightened and relaxed cognitive condition,but with tightened-relaxed cognitive styles.

Objective To investigate the surgical treatment of Maisonneuve injury associated with posterior malleolus fracture under direct visualization via the posterolateral approach.Methods Between January 2008 and June 2015,27 patients with Maisonneuve injury associated with posterior malleolus fracture were treated at our department.They were 18 men and 9 women,aged from 20 to 60 years (average,40.1 years).All fractures and syndesmoses received open reduction under direct visualization and internal fixation via the posterolateral approach.The posterior malleolus fractures were fixed with screws or plate and the syndesmoses fixed using cortical bone screws.Functional results were evaluated using the Baird-Jackson ankle scoring system.Results The patients were followed up for 8 to 30 months (average,18 months).No wound infection,necrosis,dehiscence,lose of reduction or implant failure was found during follow-up visits.All cases got bony union at the last visit.The excellent and good rate was 92.6％.Conclusion Since the posterolateral approach allows good access to the Maisonneuve injury and posterior malleolus fracture under direct visualization,it facilitates accurate direct fracture reduction,stable fixation and early exercise.

The case of LI Li-yun involves the right of life,the right of informed consent and the special right to intervene from the inspection of right.By analyzing the concepts of three kinds of rights and discussing the conflicts between the right of informed consent,the right of life,and the special right to intervene,it presents the principles of equity of right and the measures of legal insurance which are essential conditions to end this kind of tragedy.

OBJECTIVE:To study the contents of the medicinal components in Artemisia annua from different habitats.METHODS:A total of 22 batches of Artemisia annua samples from different habitats throughout China were collected with artemisinic acid,arteannuin B,artemisinin and scopoletin determined by HPLC.The contents of the constituents were taken as indexes to conduct correlation analysis and cluster analysis.RESULTS:The results of correlation analysis and cluster analysis showed that there were marked differences in the contents of the above-mentioned 4 constituents in Artemisia annua from various habitats.CONCLUSION:Accumulation of active ingredients of Artemisia annua is correlated to the habitats to some degree.

OBJECTIVE:To evaluate the present situation and trend of the antidepressants.METHODS:The antidepres?sants drugs in21hospitals of Hangzhou during2000～2003was statistically analyzed with respect to sales sum,market struc?ture etc.RESULTS:The total amount for antidepressants increased dramatically year by year.The consumption of the im?ported antidepressants has been decreasing while that of the domestic has been increasing and that of the antidepressants from the joint ventures remained stable.CONCLUSION:There is a great potential for the development of antidepressants;the sales amount and the consumption sum take on a trend of increasing rapidly.