Field application of mosquito nets impregnated with Fendona (alphamethrin) was con-ducted in Jiangpu,Liuhe and Yizheng counties (city) during 1992 in order to control malaria and mosquito vector. Three groups were set for control,i.e. ,using mosquito nets impregnat-ed with deltamethrin, DDT spraying,and a group without preventive measures. The result showed that density of mosquito vector declined significantly after using of mosquito nets im-pregnated with Fendona. Mosquito density declined by 71. 58% ,the long-term efficiency last-ed more than 4 months,and local malaria incidence declined by 72. 73%. The effect of this measure was similar with that of using mosquito nets impregnated with deltamethrin, and was much better than that of DDT spraying. Since Fendona is a cheap,odourless,and effec-tive insecticide it is worthwhile to be recommended in malaria control program in the field.

Objective To explore the clinical value of heart-type fatty acid binding protein testing (H-FABP) in the diagnosis of early myocardial ischemia injury.Methods One hundred and eighty cases diagnosed with myocardial ischemia from January 2016 to December 2016 were selected as the experimental group,then according to the disease time,the subjects were divided into the earlier group(≤3 h),middle group(3~6 h)and later group(≥6 h),each group 60 cases.180 cases with healthy physical examination results were enrolled in the control group.The concentration of serum H-FABP and IMA were detected in order to analyze the clinical value comprehensively.Results Compared with the control group,the concentration of serum H-FABP ((11.54±4.31) μg/L) and IMA ((92.72±5.31)U/ml) in the experimental group increased greatly,the differences were statistically significant(t=2.305,3.001,P<0.05).Among the subgroups in the experimental group,the concentration of IMA was the highest in the early stage and decreased in the middle and later stages,and there were significant difference between the earlier group and later group(t=2.326,P<0.05).The concentration of serum H-FABP and IMA in the experimental group and control group were positively correlated (r=0.9237,P<0.05).Positive detection rate analysis showed that the positive rates of H-FABP and IMA among the subgroups were above 80.00%,and the positive rate of combined detection was obviously improved (P<0.05).The clinical diagnosis was used as the gold standard,the Kappa of the results of H-FABP detection and clinical diagnosis was 0.85 (P<0.05).Conclusion H-FABP has a positive clinical significance in the diagnosis of early myocardial ischemia,as IMA has high positive detection rate,and has high consistency with clinical diagnosis results,it can effectively reduce the misdiagnosis rate and combined detection can reduce the rate of missed diagnosis.

Objective To understand the basic situation of blood donors and their anti-HIV antibody screening in a hospital of Madagascar during 2008- 2009 in order to provide the reference information for giving better medical aid and promoting the devel-opment of the clinical transfusion in Madagascar.Methods The blood doner′s personal informations were understood by inquiry and the anti-HIV antibody was detected by the rapid testing,the results were recorded,the constituent ratio of the data was calcu-lated and the chi-square test was performed.Results There were 2 298 blood donors including teenages less than 15 years old dur-ing 2008-2009,female doners were more than male donors,among them 366 cases were pregrant women.The blood donors from village were more than those from city,the education level was dominated by the middle school students,accounting for 51.65%. There were 22 tuberculosis patients in 2008,none in 2009.The detection rate of anti-HIV antibody was 0.04% for these 2 years. Conclusion The protection on the blood donors in Africa area is not optimistic.The phenomenon of pregrant women and teenages as the blood donors exists in Madagascar.

Objective To observe the efficacy of ganglion glycosides in the treatment of elderly patients with Parkinson's disease and its influence on the serum tumor necrosis factor -alpha(TNF -α).Methods 60 elderly patients with Parkinson's disease were selected,and according to the different treatments,they were randomly divided into the observation group(n =30)and control group(n =30).The control group was given routine treatment,and the observation group was given ganglion glycosides treatment on the basis of routine treatment.The comprehensive rating scale score changes were observed,and the curative effect,serum TNF -αlevel changes were compared between two groups.Results The total effective rate of the observation group was 53.3%,which was higher than 23.3% of the control group(χ2 =6.721,P <0.05).After treatment,Parkinson's disease rating scale score of the indexes (spirit, behavior,emotions and daily activities and motor function)of the two groups were significantly lower(t =3.571, 5.726,7.153,all P <0.05).The serum TNF -αconcentrations before and after treatment of the observation group were (27.4 ±6.1)μg/L,(13.1 ±3.4)μg/L,respectively,and those of the control group were (27.6 ±6.0)μg/L, (20.3 ±4.7)μg/L respectively.After treatment,the serum TNF -αlevels of the two groups were significantly lower than before treatment (t =5.614,8.352,all P <0.05 ),and after treatment,the serum TNF -α level of the observation group was significantly lower than that of the control group (t =4.241,P <0.05).Conclusion Ganglion glycosides in the treatment of elderly patients with Parkinson's disease can make slow markedly improved,lower levels of serum TNF -α,has significant clinical therapeutic effect.

Objective　To improve the treatment effect of primary hepatic cancer (PHC). Methods　Analysis of the influential factors on treatment effect of PHC in China, and propose the countermeasure. Results and Conclusions　The main factors influencing the treatment effect of PHC in China are the followings: (1) Most patients with PHC of subclinical type failed to be diagnosed and treatment in time. (2) As a wrong idea PHC has been considered an “uncurable disease", so the treatment strategy is nagative. (3) Unsuitable choice of treatment resulted in some PHC unable to be resected. (4) Intraoperative massive bleeding due to unskill-operative techniques, increase the postoperative morbidity and mortality. (5) The manner of treatment is not positive for PHC patients with portal cancer thrombosis, bile duct cancer hteombosis and portal hyperlension. (6) Combined therapy can not be used or unsuitably used. The following things should be done in order to improve the treatment effect of PHC: (1) Strengthening improving the health-protective consciousness of people and regular examinaton of “high risk" population. (2) Renewing the professional knowledge in time to improve the level of diagnosis, treatment and operative techniques of medical personnel. (3) strengthening the basic medical research to make a break through in PHC treatment.

Objective:Cardiac index(CI) and mixed venous oxygen saturation SvO2 were studied in 85 patients undergoing coronary artery bypass grafting(CABG). Methods: Measurement of CI and SvO2 was carried out with a fiberoptic ballon-tip thermodilation pulmonary artery catheter. Fentanyl-based anesthesia was applied in all patients. Hemodynamic parame-ters were obtained prior to anesthesia induction as the baseline, after endotracheal intubation, after stemotomy, after weaning of cardiopulmonary bypass, at 6 and 24h after operation. Results: CI and SvO2 increased or was not changed at all time intervals, compared with the baselines. The changes of SvO2 correlated well with those of CI. Conclusion: The results suggest that continuous monitoring of SvO2 may be useful to predicting alteration in CI in patients undergoing CABG.

Objective To study the impact of nursing intervention on the sleep quality of postoperative elderly patients who had sleep disorder. Methods 260 cases of postoperative elderly patients with sleep dis-orders were randomly divided into the experimental groupand the control group with 130 cases in each group. Conventional care was given to the control group, the experimental group received appropriate nursing interven-tion such as psychological nursing, rehabilitation,etc. Pittsburgh sleep quality index (PSQI) was used to evaluat-ed sleep quality of two groups before and after intervention, t test was adopted. Results No difference was seen in each sleep index in the two groups. While each index evidently alleviated after intervention in the ex-perimental group and was better than those of the control group. Conclusions Nursing interventions have certain effects on improving sleep quality of postoperative elderly patients with sleep disorders.

Objective To investigate the characteristics of pathogenic bacteria and drug resistance and susceptible factors of pulmonary infection in patients with severe brain injury and to provide a guideline for the prevention and control of infection.Methods Bacteria culture results combined with clinical data of pulmonary infection in patients with severe brain injury were analyzed retrospectively in our hospital from Jan.2004 to Dec.2008.Results The patients with severe brain injury were often complicated by pulmonary infection.Gramnegative bacilli were main pathogenic bacteria leading to pulmonary infection ( 74.8% ),including pseudomonas aeruginosa ( 21.0% ),Escherichia coli ( 16.5% ),baumanii ( 13.6% ),pneumobacillus ( 7.7% ),enterobacter cloacae (6.3% ) and others.Thirty-nine Gram-positive bacilli were observed including Staphylococcus anreus,coagulase negative staphylococcus,enterococcus and others.There were 21 fungus infection observed.Conclusions Overall and systematically monitoring the condition of pathogenic bacteria distribution and drug resistance of pulmonary infection in patients with severe brain injury have important significance to select antibiotics and effectively prevent and control pulmonary infection.

Under the high pressure of employment, traditional teaching method that is based on inculcating the knowledge to students does not adjust current condition any more. So, we start to looking for a new, more suitable way of teaching.--Project Based-on Learning, and have analyzed the advantages in health information technology teaching by construction doctrine in combination with the concept and principle in wedlock construction. At the same time we introduce project Based-on Learning in concrete application to find a way to put the theory into practice.

Objective To investigate the correlation between adiponectin, CRP and homocysteine (Hcy) and evaluate its mechanism in acute cerebral infarction. Methods Serum adiponectin, hs-CRP,Hcy, blood lipid, FPG and blood pressure were measured in eighty patients with acute cerebral infarction ( cerebral infarction group) and eighty healthy persons ( control group). Results In cerebral infarction group, serum hs-CRP, Hcy, TG , and systolic pressure were significantly higher than in control group ( P ＜0. 05) , while serum adiponectin were significantly lower than in control group ( P ＜0. 05). Serum adiponectin levels were negatively correlated with Hcy( r = -0. 453) , hs-CRP ( r = -0. 397) ,TG( r = -0. 321) , FPG( r = -0. 318) and systolic pressure ( r = -0. 288). Conclusion There is correlation between adiponectin, Hcy, hs-CRP, glucose and lipid metabolism and blood pressure, which plays a role in occurrenc and development of acute cerebral infarction.