1.Clinical progresses of imaging-guided robot in minimally invasive treatment
Chinese Journal of Interventional Imaging and Therapy 2017;14(5):310-313
Image-guided minimally invasive treatments play an increasingly important role in clinical works.With the progressing of science and technology,image-guided robot technology are mature gradually.It can accomplish parts of clinical minimally invasive treatments,and make up for the deficiencies in the process of surgery.Present situation and application in minimally invasive treatments of image-guided robot system were reviewed in this article.
2.The efficacy of the electrolyzed oxidizing water in the oral irrigation of patients with oral trachea can-nula
Chinese Journal of Practical Nursing 2009;25(26):12-14
Objective To study the efficacy of the electrolyzed oxidizing water (EOW) in the oral irrigation of patients with oral trachea cannula. Methods 60 patients with oral trachea cannula were ran-domly divided into the experimental group and the control group, the experimental group received oral irri-gation with EOW,while the control group used normal saline. The oral irrigation efficacy was compared be-tween the two groups. Results In the experimental group,the bacterial clearance rate was 95.21% ,while the control one's was 37.19%, the stomatodysodia rate of the experimental group was 3.33%, the control one's was 86.60%, the oral fungus infection rate of the experimental group was 0% , the control one's was 43.33%, the incidence of dental ulcer of the experimental group was 10.00%, the control one's was 3.33%. Significant difference existed in bacterial clearance rate and the stomatedysodia rate between the two groups. Conclusions Oral irrigation with EOW in oral trachea cannula patients can decrease or con-trol the field planting of bacterium in pharynx oralis and stomatodysodia, and prevent pulmonary infection.
3.Research advances of baby body plethysmography
Chinese Journal of Applied Clinical Pediatrics 2014;29(16):1261-1264
Baby body plethysmography is a well-established technique of lung function determination,which is widely used to access the respiratory development and obstructive airway diseases by precisely measuring tidal breathing,functional residual capacity,and air way resistance.Babies who accept lung function measurements in the baby body plethysmography are under quiet state of spontaneous breathing without any subjective initiative,which results in multiplexed data acquisition,high precision and good repeatability.Clinical application of baby body plethysmography differs in different countries and areas,with the most intensive application in the German-speaking countries.In China,the clinical use of baby body plethysmography still remains in primary stage.Great progress has been achieved in its clinical use during the past 20 years,but there is still a lack of consensus on normal reference values or equations with which to interpret results,which has caused some trouble to diagnosis and identification of respiratory disease.In order to identify the nature and severity of airway disease,it is essential to understand the normal range of plethysmographic values that may occur in healthy infants of similar age,gender and body size.
4. Future hot spots for cartilage repair: Laminin promotes stem cell proliferation
Chinese Journal of Tissue Engineering Research 2020;25(1):141-145
BACKGROUND: The characteristics of laminin that can promote the proliferation of stem cells have been widely concerned. OBJECTIVE: To review the interactions between laminin and many different stem cells, and provide reliable theoretical basis for chondrogenic research and application of stem cells. METHODS: Wanfang, CNKI, PubMed and Web of Science databases were searched for articles related to mechanism of laminin, changes in stem cell behaviors, and cartilage regeneration published from January 2010 to October 2019. The retrieval terms were “laminin” and “steam cells” in Chinese and English. Duplicated and poorly related articles were excluded, and finally 57 articles were included for review. RESULTS AND CONCLUSION: (1) The structural characteristics of laminin were summarized. The spatiotemporal changes of laminin during cartilage development and degradation were analyzed. At the same time, the distribution of laminin expression in natural cartilage tissue and tissue engineered cartilage tissue was compared. (2) The effects of laminin on the proliferation of various stem cells, including embryonic stem cells, induced pluripotent stem cells and adult stem cells, were described. (3) The possible hotspots on the combination of laminin and stem cells for cartilage regeneration were proposed, with the attempt of providing theoretical basis for cartilage repair and regeneration in the future.
5.Identification of Guangdongzizhu in Kanggongyan Tablets by TLC
Xiaobo ZHANG ; Xin MAO ; Wenbo ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2008;0(S1):-
Objective To establish a method for TLC identification of Guangdongzizhu in Kanggongyan tablets. Method Developer was chloroform-methyl alcoho-Formic acid (20∶4∶0.8), spraying with the test solution of chloride ferric. Result The same color spots in the TLC graphs of sample existed at the corresponding position compared with the control. Conclusion The method is proved to be sensitive and precise, and can be used for the quality control of Kanggongyan tablets.
6.Gene module analysis of nasopharyngeal carcinoma based on protein-protein interaction network
Shu ZHANG ; Xiaobo CUI ; Juan SUN
Journal of Regional Anatomy and Operative Surgery 2016;25(11):781-783,784
Objective Based on protein-protein interaction network,gene modules were identified to provide new targets for molecular therapy of nasopharyngeal carcinoma.Methods GEO dataset (GSE12452)and SAMsoftware were employed to screen the differentially ex-pressed gene in nasopharyngeal carcinoma.Protein-protein interaction network was established by using String database.Based on the net-work,the gene modules were identified by using bioinformatics gene module analysis method.GO analysis was used to analyze the function of gene modules.Results In this study,2 634 differentially expressed genes were identified in nasopharyngeal carcinoma.There were 4 729 protein-protein interaction pairs among the differentially expressed genes according to the String database.We established the protein-protein interaction network based on these pairs.Seven gene modules were identified by bioinformatics methods.GO analysis results showed that the function of the gene modules including regulation of cell cycle,glycosylation,cell adhesion,oxidation reduction and so on.Conclusion There are 7 gene modules in protein-protein interaction network in nasopharyngeal carcinoma.These modules may play important roles in the progression and development of nasopharyngeal carcinoma.Our finding can provide a new sight for molecular diagnose and therapy of nasopharyngeal carcinoma.
7.Prospective study of the treatment of adenomyosis by combining hysteroscopic transcervical resection of endometrium with levonorgestrel-releasing intrauterine system
Fuqiang CHEN ; Aifeng ZHANG ; Xiaobo WANG
Journal of Shanghai Jiaotong University(Medical Science) 2017;37(5):641-645
Objective · To explore the clinical application value of hysteroscopic transcervical resection of endometrium (TCRE) combined with levonorgestrel-releasing intrauterine system (Mirena) in the treatment of adenomyosis. Methods · A total of 112 cases of adenomyosis patients were divided randomly into the combination group and Mirena group. The combination group (56 cases) was treated by TCRE endometrium endometrial resection, assisted Mirena treatment after operation. Mirena group (56 cases) was treated by Mirena only. The follow-up lasted 36 months after treatment, including measures of the volumes of menstrual bleeding, hemoglobin levels, dysmenorrhea scores, uterine volume, serum CA125 levels and incidences of complications.Results · The median follow-up duration was 42 months, and the three-year follow-up rate was 73.21% for the combination group and 50% for the Mirena group. After surgery, the volumes of menstrual bleeding of patients in 3-36 months decreased significantly, with an increase in hemoglobin level and a decrease in serum CA215 level and dysmenorrhea scores. Compared with their situations before surgery, the difference was significant (P<0.05). A comparison of uterine volume before and after surgery showed that there is a significant decrease in the uterine volume in both groups in6-12 months after surgery (P<0.05).Twenty-four months after surgery, it shows thatthe combination group has a much more significant decrease in uterine volume [(171.3±34.8) mm3] than Mirena group [(213.7±38.6) mm3] (P<0.05). The hysterectomy rate in Mirena group was significantly higher than that in the combination group (12.50% vs 5.36%); the ring expulsion rate was 16.07% in Mirena group and 5.36% in the combination group, and the break through bleeding happeningrate was 8.93% in Mirena group and 3.57% in the combination group. After 36 months an irregular small amount of vaginal bleeding rate was 62.25% in Mirena group, while it was only 12.50% in the combination group. There was significant differencewhen comparing above indices between two groups (P<0.05). There was no obvious differences in most common side effects of both groups. Conclusion · HysteroscopicTCRE combined with Mirena reduces significantly the irregular menstrual bleeding caused by merely applying Mirena. It has a prominent clinical efficacy and can be an effective approach in treatment of adenomyosis.
8.Philosophical meditation on mental health
Xiangkui ZHANG ; Ying PAN ; Xiaobo CONG
Chinese Journal of Tissue Engineering Research 2005;9(12):248-251
AIM: This paper, starting from the perspective of "human beings' living world", tries to reveal the historical epoch premise of mental health and redefines the criteria of mental health by "harmonization of human beings'relationships".METHODS: Sorting out the criteria of mental health by studying a large numbers of literatures.RESULTS: Four kinds of harmonious relationships in human beings' living world are disclosed, namely, the symbiosis of man and nature, the interaction between man and man, the integration of human beings and their egos, and the signification of mental health by inosculating man and "god".CONCLUSION: Grasping the real philosophical connotation of mental health to focus on human beings' realistic life quality through "the fashion of man".
9.Study of Chlamydia trachomatis infection on cervical secretion of women with early pregnancy and secondary sterility
Xiaobo SHI ; Fengying LIU ; Hongwen ZHANG
Journal of Central South University(Medical Sciences) 2001;26(2):169-170
Objective This study was to investigate the Chlamydia trachomatis (CT) infection rate in cervical secretion of early pregnant and secondary sterility women. Method CT-DNA in the cervical secretion of the early pregnant, the secondary sterility, and the control women was detected with polymerase chain reaction (PCR). Results The infection rates of CT in the early pregnant and secondary sterility women (14.28% and 13.33%)were higher than in the control women (3.33%, P<0.05),and there was no significant difference between the former two groups (P>0.05). Conclusion There are higher infection rates in the early pregnant and secondary sterility women.Detecting CT and treating in the perinatal period are needed in the early pregnant women who want to be pregnant again.
10.Climate suitable rank distribution of artemisinin content of Artemisia annua in China.
Xiaobo ZHANG ; Lanping GUO ; Luqi HUANG
Acta Pharmaceutica Sinica 2011;46(4):472-8
At the urgent request of Artemisia annua (ART) planting, the paper gets artemisinin content (ARTC) of ART in China from literatures. The paper analyses the relationships between ARTC and ecological factors by statistical analytical methods. The paper also analyses the climate suitable rank distribution of ARTC in China by ArcGIS. The results display that first, ARTC is significantly different in China, that ART from the south regions ARTC is higher. Greatest north parts of China have not suitable climate for the growing of ART and the ARTC is lower than 0.2%, when ART grows above the 34th degree of northern latitude. ARTC is higher and ART grows well, when ART grows under the 34 degrees N and grows at the areas between 100 degrees E and 120 degrees E. Second, subtropical zone is the best suitable climate zone for the growing of ART. ART grows well and ARTC is higher than 0.5%, when ART grows in the subtropical zone. Third, temperature, sunshine duration and rainfall are the main ecological factors that affect the growth of ART and the accumulation of ARTC. That the year temperature between 13.9 degrees C and 22 degrees C, sunshine duration between 853 h and 1507 h, rainfall between 814 mm and 1518 mm, is the best climate for the accumulation of ARTC. Temperature between 13 degrees C and 29 degrees C, rainfall between 600 mm and 1300 mm is the best climate for the growth of ART. Fourth, in northwest of Guangxi, eastern of Sichuan, Guizhou and Yunnan provinces, south Chongqing and west Hunan Province, there are suitable climate for the growth of Artemisia and for the accumulating of ARTC. There are also some suitable climate areas for the growing of artemisia in the south of Hubei, Anhui and Jiangsu provinces.