1.Effects of Nursing with Syndrome Differentiation and Conventional Western Medicine on Perioperative Patients with Breast Cancer
International Journal of Traditional Chinese Medicine 2009;31(3):279-280
Objective To observe effects of integrated western and Chinese nursing on postoperative complications of breast cancer. Methods 53 patients with breast cancer who were treated with radical mastectomy, were randomly divided into two groups. The control group was treated with conventional western medicine nursing, and the treatment group was treated with syndrome differentiation nursing based on the control group. The postoperative complication of two groups was observed.Results The postoperative complication of the treatment group were significantly lower than the control group.Conclusion Integrated western and Chinese nursing of perioperative patients with breast cancer, can reduce complications and improve quality of life of patients.
2.Strengthen Lab Construction and Improve Experimental Teaching Quality
International Journal of Traditional Chinese Medicine 2008;30(3):193-
Based On current situation of experimental teaching and managementin our college,this paper raised some concrete approaches of imlxoving experimental teaching levels to strengthen lab construction and experimental teaching quality
4.Effect of estrone on hippocampal neuronal apoptosis induced by NMDA in rat primary culture
Quanzhong CHANG ; Shuling ZHANG
Chinese Pharmacological Bulletin 1986;0(04):-
Aim To observe the action of estrone on the hippocampal neuronal apoptosis induced by NMDA in vitro and to analyse the mechanism underlying the neuroprotection of estrone. Methods The methods of both morphological analysis and cell viabilities were used, and Western blot was also used to analyce the role of antitoxiciy of estrone. Results The cultures were conformed with fluorescent dye of Hoechst 33258 and NeuN. About 31.6% neurons were induced into apoptosis by NMDA(300 ?mol?L~ -1 +glycine 5 ?mol?L~ -1 ,compared with control group, P0.05). MTT test also showed that estrone can protect cultures from apoptosis induced by NMDA, it can raise the cell viabilities exposed to NMDA. Western blot showed that activities of caspase-3 can be inhibited by estrone, the segments of caspase-3 can diminished after application of estrone together with NMDA. Conclusion Estrone had neuronal protection, this role maybe relate to the inhibition of caspase-3, a common pathway in apoptosis. The results can provide some clues to the explovation of the clinical use of estrone and to the development of a neuronal protective drug.
5.Nursing of 56 Cases of Perioperative Pailents with Rectal Cancer
International Journal of Traditional Chinese Medicine 2009;31(1):87-
Objective To observe the eriects of integrated traditional Chinese and western medical nursing on postoperative complications of rectal cancer.Methods 56 patients with rectal cancer treated with Miles operation were randomly divided into a control group and a treatment group.The control group was nursed with conventional western medicine,and the treatment group was nursed according to syndrome differentiation of TCM plus conventional western medicine.Results The postoperative complications of the treatment group were significantly fewer than the control group.Conclusion Integrated traditional Chinese and western nursing of perioperative patients with rectal cancer can reduce complications and improve quality of life of patients.
6.Basilar artery tortuosity and its clinical significance
Daopei ZHANG ; Shuling ZHANG ; Yuming XU
International Journal of Cerebrovascular Diseases 2012;(10):778-781
With the development of neuroimaging the detection rate of basilar artery tortuosity is significantly high.The occurrence and development processes of basilar artery tortuosity are affected by age,basilar artery length,vertebral artery dominance,and other factors.Basilar artery tortuosity may influence the blood supply of posterior circulation and cause brainstem and cranial nerve pressure leading to clinical symptoms.
7.Role of voltage-dependent chloride channels in hippocampal neuronalapoptosis induced by 3-morpholinosydnonimine in rats
Quanzhong CHANG ; Shuling ZHANG ; Jinbao YIN
Chinese Journal of Pharmacology and Toxicology 2010;24(1):8-12
OBJECTIVE To explore the effect of chloride channels on the neuronal injury following cerebral ischemia. METHODS Tweleve day in vitro (12dIV) neurons in rats were randomly divided into normal control, 3-morpholinosydnonimine (SIN-1, 1.0 mmol·L~(-1) for 18 h) group, SIN-1+4-acetamido-4'-isothiocyanatostilbene-2,2'-disulphonic acid(SITS, 0.5 mmol·L~(-1)) group and SIN-1+4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS, 0.1 mmol·L~(-1)) group. Drugs were added with SIN-1 simultaneously and coincubated for 18 h. The neuronal apoptosis and morphological changes were detected with Hoechst 33258. Chloride channels(ClC)-2/ClC-3 were analyzed with immunofluorescence, the chloride channel currents were recorded with whole cell patch-clamp technique. RESULTS Hoechst 33258 staining showed that the apoptotic percentages were (18.61±0.59) %, (50.43±0.56)%, (23.37±0.52)% and (23.37±0.84)% in normal control group, SIN-1 group, SIN-1+SITS or SIN-1+DIDS groups, respectively. ClC-2/ClC-3 were positively expressed in normal neurons. The currents in neurons exposed to SIN-1 were increased about 55%-56%, SITS and DIDS, two kinds of chloride channel blockers could inhibited the currents about 50%-60% and 30%-40%, respectively. CONCLUSION Voltage-dependent chloride channel maybe participate in the neuronal apoptosis induced by NO, and the activities of chloride channels are perhaps involved in the cerebral ischemic injury.
8.Approach of Improving Medical Students′Doctor-patient Communication Skills under the ESP Teaching Theory
Ying LIU ; Shuling ZHANG ; Lili ZHU
Chinese Medical Ethics 2015;(4):536-538
As the global economic integration, the trend of internationalization of medical education, social demand for foreign talents is more and more big, the English teaching, especially the doctor-patient communication in English teaching has become a major focus on the teaching content.Learning is the study of doctor-patient communication be-tween medical workers and patients how to mutual understanding, trust and cooperation, common a discipline, to conquer the disease and emphasize ability oriented ESP teaching concept, closely integrated with professional, promotes the student as the center, apply English teaching as means and tools to study, the two organically unifies in together.Practice shows that guided by the ESP teaching concept, improve medical students English power of expression of doctor-patient commu-nication attempt made substantial results.
9.Basilar artery hypoplasia and its clinical significance
Daopei ZHANG ; Shuling ZHAGN ; Yuming XU
International Journal of Cerebrovascular Diseases 2015;23(1):75-78
Basilar artery hypoplasia (BAH) has been paid less attention to in the past.However,the increased detection rate makes the clinical significance of BAH to be gradually recognized.BAH have interaction with vascular risk factors,and this may promote the occurrence of ischemic events in posterior circulation.Brain evoked potential can be used as an important means for early detection of this pathophysiological events.The depth study of pathological significance of BAH helps to deepen the understanding of the mechanisms of posterior circulation ischemic events.
10.Analysis the Positive Role of Speech Act Theory in Promoting the Oral English Skills of Doctor-patient Communication
Ying LIU ; Shuling ZHANG ; Lili ZHU
Chinese Medical Ethics 2015;(5):734-736
By analyzing the problems existing in the practice of doctor -patient communication , respectively discusses the speech act theory before the implementation of the implementation of doctor -patient communication oral English training , implementation , and after implementation of the positive role: instant help medical students to master a large number of medical English vocabulary;In view of the students come from different areas , instant help correct the pronunciation and intonation;Benefit based on speech act theory to guide the student to carry on the different roles played in English oral practice helps students to adopt direct and indirect speech act theory and the method of the oral English practice for communication;To improve medical students′professional recognition;To strengthen the medical students′sense of mission .