Objective: To explore the correlation of overweight, obesity and hypertension with fast resting heart rate (RHR3>100 times/min) among college freshmen in different genders, and to provide scientific reference for early prevention and control for cardiovascular disease. Methods: In September 2016, 4 362 college freshmen were measured by height, weight, blood pressure and RHR to observe the distribution of fast RHR and analyze the effects of overweight obesity and hypertension on fast resting heart rate of freshmen of different genders. Results: The detection rate of fast resting heart rate of college freshmen was 1.81%, that of male students (2.03%) was higher than that of female students (1.62%), and the difference was not statistically significant (χ2=0.99, P>0.05). fast RHR increased with body mass index (BMI) and blood pressure. After adjusting other risk factors, for male freshmen, the risk of fast RHR in overweight and obesity were 1.13 fold (95%CI：1.05-2.59) and 2.87 fold (95%CI：1.99-4.88) higher than that of the healthy people. For females, the risks were 1.34 fold (95%CI：1.11-2.85) and 3.83 fold (95%CI：2.12-8.84). In comparison to the normal blood pressure group, the ALT abnormal rate of the high blood pressure group was 15.52 fold higher in male freshmen and 17.81 fold higher in females. Conclusion Overweight, obesity and hypertension were positively correlated with fast RHR among college freshmen. Hypertensive patients have a high risk of fast RHR. Monitoring BMI and blood pressure is helpful to prevent and control cardiovascular disease.