1.Association between echocardiography utilization and prognosis in patients with cardiac arrest
World Journal of Emergency Medicine 2025;16(1):63-66
Despite efforts to develop treatment technology for cardiac arrest (CA), CA incidence and mortality rates are still high.[1,2] A recent study of CA patients in emergency departments revealed that the incidence of CA is increasing annually, and the in-hospital survival rate of CA patients is only approximately 28.7%.[3] Echocardiography has been widely used as an important monitoring tool in critical care and helps to identify the cause of shock, monitor hemodynamics, and guide fluid therapy utilization.[4] One study reported that approximately one-third of patients underwent formal echocardiography during hospitalization in the intensive care unit (ICU).[5]
2.Practice and exploration of conformational memory method in teaching of laboratory animal science
Chinese Journal of Medical Education Research 2012;(12):1226-1228
Laboratory animal science has become a main support for the development of life science and has occupied an importance place in higher medical education.The paper analyzed the characteristics and problems of laboratory animal science and proposed the ideas of applying conformational memory teaching in laboratory animal science teaching from there aspects:teaching method,teaching frame and teaching effect.These measures established the foundation for the cultivation of applied talents with comprehensive competence.
3.Value of PET/CT for diagnosis of recurrence and metastasis of differentiated thyroid carcinoma
Journal of Endocrine Surgery 2015;(2):136-139
Objective To analyze the value of PET/CT for diagnosis of recurrence and metastasis of dif-ferentiated thyroid carcinoma ( DTC) .Methods 65 patients with DTC in Thyroid Surgery Department of the First Affiliated Hospital of Zhengzhou University from Dec .2005 to Jan.2015 were collected.Based on the values of serum thyroglobulin(Tg),the patients were divided into 2 groups.29 cases with positive Tg were the observation group and 36 cases with negative Tg were the control group .All patients underwent PET/CT examination one year after surgery.Patients with positive findings from image studies underwent surgical excision and postoperative pathological diagnosis .Clinical data of the 2 groups were then summarized and discussed .Results There was no significant difference on the general conditions between the 2 groups(P>0.05).Tg values were statistically dif-ferent 6 months and 1 year after surgery between the 2 groups(P<0.05).Tg values of both groups decreased 1 year after surgery, but without statistical difference (P>0.05).9 cases in the observation group and 1 case in the control group had positive findings on image study .All the cases with cervical lymph nodes presented as high uptake of 18 F-FDG.All patients who had positive findings on PET/CT underwent surgical removal of the abnormal lymph nodes which confirmed by pathology as lymph node metastasis .Conclusion PET/CT is very important for diagno-sis of recurrence and metastasis on Tg(Tg>2μg/L)positive,131I Dx-WBS imaging and US negative patients.
4.Comparison of Mental State and Drug Safety of Puerperant Underwent Propofol and Etomidate Painless Abortion after Regain of Consciousness
Zhongqing NAN ; Mingxiao ZHANG
China Pharmacy 2015;(26):3684-3686,3687
OBJECTIVE:To compare mental state and drug safety of puerperant underwent propofol and etomidate painless abortion after regain of consciousness. METHODS:102 puerperant underwent painless abortion were selected and randomly divided into control group and trial groups with 51 cases in each group. The control group received Propofol injection 2 mg/kg intravenous-ly,and the trial group received Etomidate fat emulsion injection 0.2 mg/kg intravenously. The changes of patient’s mental state were evaluated with Positive and Negative Emotions Scale (PANAS) before anesthesia and after regain of consciousness. The changes of HR,BP,MAP and SpO2 were observed and compared between 2 groups before anesthesia and 1,2,3 and 5 min after anesthesia. The anesthetic effect and ADR were compared between 2 groups. RESULTS:Compared to before anesthesia,positive mood scores of the trial group were increased slightly after regain of consciousness,while that of the control group were increased significantly;there was statistical significance before anesthesia and after regain of consciousness (t=9.023,P<0.05);there was statistical significance between 2 groups(t=8.367,P<0.05). Negative mood scores of 2 groups were decreased significantly af-ter regain of consciousness;there was statistical significance before anesthesia and after regain of consciousness(t=8.672,9.895, P<0.05). HR,BP MAP and SpO2 of 2 groups had no statistical significance within 5 min after anesthesia(P>0.05). The total effective rate of anesthesia in control group was 80.4%,while that of trial group was 78.4%;there was no statistical signifi-cance between 2 groups (χ2=1.273,P>0.05). The incidence of nausea,vomiting,dizziness and other ADR were similar in 2 groups,but the incidence of fantasy(39.2%)in control group was significantly higher in trial group(11.8%);there was statistical significance between 2 groups(χ2=10.120,P<0.05). CONCLUSIONS:Propofol and etomidate have good stability on the respira-tory and circulatory system,anesthetic effects are correspond to the incidence of ADR. Etomidate has a better safety. But the psy-chological status of patients in the propofol group is preceding than etomidate group.
5.Comparison of Regulation on GM Crops Cultivation Management in USA and China
China Biotechnology 2017;37(8):119-127
The proposal to promote the commercialization of new insect-resistant GM cotton,GM corn and other major products in 13th Five Year Plan on National Science and Technology Innovation ,has put forward a test to the government's ability to manage GM crops cultivation.Only a few species of GM crops,not including food crops,have been commercialized in China,we lack experience in GM crops cultivation management.Taking USA,where the farmers cultivate huge areas of GM crops,as a comparison object,the examination and approval procedures before cultivation,GM crop growers' obligation of the management,the methods to reduce mingling of GM crops and non-GM crops are compared.And concludes that the differences in legal status of GM crops,the intellectual property regime and labeling regulation,the ability of relative stakeholders to implement segregation measures and bear loss lead to different regulation on GM crops cultivation management in USA and China.The government combine the domestic current situation of the agricultural environment in our country,and focus on substantial risk in the safety management of GM crops in cultivation management is advised.The competent department of agriculture,researchers and seed traders should work together to help guide growers to avoid the economic disputes due to mingling and reduce the impact on the ecological environment.
6.X-ray Diffraction analysis with Fourier pattern of Qingdai Powder
Chinese Traditional and Herbal Drugs 1994;0(12):-
Objective To establish a new method to identify and analyze Qingdai Powder and its composition.Methods X-ray Diffraction with Fourier pattern was used.Results The standard X-ray diffraction with Fourier pattern and characteristic diffraction peaks of Qingdai Powder and its composition drugs were obtained.Conclusion The powder X-ray diffraction method can be used as a simple and convenient method for the identification of Qingdai Powder and its composition drugs.
7.Research the expression of NF-?B and apoptosis of neutrophils induced by TNF-? treated with Lidocaine
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(12):-
AIM:To observe the effect of lidocaine to the activation of NF-?B and apoptosis in human neutrophils(PMN)in vitro.METHODS:Human PMN were divided into five groups:control group(0.9% sodium chloride);TNF-?(200 ng/L);TNF-?+lidocaine(1.0 mmol/L);TNF-?+lidocaine(2.0 mmol/L),and TNF-?+ lidocaine(4.0 mmol/L).The expression of NF-?B subunit p65 mRNA in the nuclear and I-?B mRNA in the cytosol extracts were analyzed by Western blotting,after co-incubation for 3 h and the content of p65 protein were observed by RT-PCR.PMN apoptosis was detected on flow cytometry after co-incubation 12 h and 24 h.RESULTS:The expression of NF-?B mRNA was significantly decreased and the expression of I-?B mRNA was markedly increased in lidocaine groups(P
8.Evaluation System of Management Efficiency of Hospitals' Medical Instruments
Chinese Medical Equipment Journal 2003;0(11):-
Objective To evaluate the efficiency of the management of medical equipment. Methods Ergonomics was applied to analyze the influence of Man-Machine-Environment System. Results Based on the actual cases, the improved procedure for equipment quality was realized and the management of purchase items were evaluated in quantification. Conclusion The efficiency of the management of medical equipment can be evaluated by using this method.
9.Analgesia Effect of Low-dose Ketamine Combined with Sufentanil after Radical Surgery of Esophageal Can-cer
Zhongqing NAN ; Mingxiao ZHANG
China Pharmacy 2015;(30):4215-4217
OBJECTIVE:To investigate the analgesia effect of low-dose ketamine combined with sufentanil after radical sur-gery of esophageal cancer. METHODS:Totally 153 patients of pre-implementation esophageal cancer surgery were randomly divid-ed into group A,B and C. After induction of anesthesia in patients in each group,patients in group A administered sufentanil 2 μg/kg;group B were treated with sufentanil 2.5 μg/kg;group C were treated with sufentanil 2 μg/kg + ketamine 85 μg/(kg·h). Visual analog(VAS)score and Ramsay score before and after anesthesia 4,8,16,24 and 48 h,analgesia pump pressing times and inci-dence of adverse reactions in each group were observed. RESULTS:Ramsay score in 4,8 and 16 h in each group were significant-ly higher than before anesthesia,the differences were statistically significant(P<0.05),however,compared with before,there was no significant difference in the Ramsay score in 48 h among each group(P<0.05);VAS scores in each group(except for group C in 48 h) at each time point were significantly higher than before,group C
10.Study on the Quality Standard of Shexiang Qutong Liniment
China Pharmacy 2016;27(12):1689-1691
OBJECTIVE:To improve the quality standard of Shexiang qutong liniment. METHODS:TLC was used for qualita-tive identification of Resina draconis and Rehmannia. The determination of total solids and ether-soluble extracts in the preparation was detected. GC was used for the content determination of muscone:the column was Thermo-TG-WAXMS capillary column by programmed temperature,the detector was FID detector,the detector temperature was 250 ℃,inlet temperature was 200 ℃,carri-er gas was high purity nitrogen at a flow rate of 1.0 ml/min,split ratio was 5:1,and the injection volume was 1 μl. RESULTS:The TLC pots of R.draconis and Rehmannia were clear with good separation. The total solids in preparations were not less than 0.6%,and extracts were not less than 3.0%. The linear range of muscone concentration was 15.21-243.36 μg/ml(r=0.9998);RS-Ds of precision,stability and reproducibility tests were lower than 2%;recovery was 97.70%-99.63%(RSD=0.78%,n=6). CON-CLUSIONS:The established method can be used for the quality control of Shexiang qutong liniment.