For making a juvenile personality norm of Changzhou Prefecture, an investigation of 737 normal juveniles sampling according to the population data of Changzhou Prefecture, using revised EPQ as a assessment instrutment, was carried out from Nov. 1988 to Jan. 1989. The results are as follows: (l)There was a relationship between some subscale scores and sex, especially the P-subscale more prominent. (2) P-subscale and N-subscale in female showed a positive correlation with the age, while L-subscale showed a negative correlation with it. (3) Most subscale scores showed a difference from National Norm. (4) Medium form of personality was most frequent seen, as compared with introvert form and tendency to extrovert form. (5) Emotional stability also showed more stable in medium group, as com- pared with unstable group and tendency to stable .group. (6) The authors suggest that above data may be used as a reference index for juvenile personality norm of Changzhou Prefecture.

Objective microRNA (miRNA) are a class of small molecule non-coding single-stranded RNA,and about 22 nucleotides (nt);lncRNA is a class of non-coding RNA long chain that longer than 200 nt,both of miRNA and lncRNA can regulate many kinds of genes' expression under different levels.This paper reviewed relationship of miRNA/lncRNAexpression level and depressive disorder,and to explore theirpredictive effects of antidepressantpharmacodynamics.Methods By retrieving literature in database of PubMed,ScienceDirect in February,March 2015 using microRNA,lncRNA,depressive disorder,antidepressants,biological markers as searching words and (depressive disorder OR antidepressant) and all field:miRNA/lncRNA as index strategy,based on literature retrieving,we acquired 87 articles and totally enrolled 50 close related articles as reviewing materials by literature screening.Results Existing studies suggested that miRNA and lncRNA may be involved in pathophysiology of depression,and miRNA may play a key role in antidepressant treatment.miRNA or lncRNA as biomarkers may be associated with depression.Conclusion Researches on miRNA or lncRNA shed light on pathological mechanism of depressive disorder and antidepressantpharmacodynamics.miRNAcan function in synaptic plasticity,sensitivity of stress reaction,production of neuron and brain-derived neurotropic factor,recovery of neural function after antidepressant treatment,while lncRNA has regulatory effects on chromosome remodeling,histone modification,Transcriptioninterference andactivation.

Objective To develop a prediction scale for mental disorders in servicemen, and examine the reliability and validity of this scale. Methods The mental disorders prediction scale was developed by exploring the risk factors inducing the mental disorders. The initial scale included 11 subscales and 102 items. One thousand and four hundreds of soldiers were chosen by random cluster sampling, and tested with this scale, of whom 54 soldiers were tested with Chinese Military Mental Health Scale (CMMHS), 61 with Eysenck Personality Questionnaire (EPQ) at the same time, and 53 were retested after 1 week. The reliability and validity of the scale were examined by Exploratory Factor Analysis and Correlation Analysis. Results According to the results of factor analysis, 11 factors were extracted, named unhealthy defense mechanism, psychosis, depression, personality disturbance, mania, social support deficiency, introversion, family and past history, stressor, neurosis, and growth experience, respectively, and there were 96 items in the formal scale when one lie factor was added. The test-retest correlation coefficients of total scale and subscales were 0.397-0.867 (P

Objective To analyze the reliability and validity of the core competence scale A for military personnel.Methods Three thousand and five hundred healthy soldiers volunteered to complete the core competence scale A for military personnel,and data were analyzed by AMOS7.0 and SPSS16.0 program.Results The confirmatory factor analysis for structure validity of all factors showed that 11 items with higher cross loading should be deleted according to its modified index,thus the revised scale was composed of 7 factors,21 competence components,65 items and one added lie subscale.Furthermore,the theoretical model of the scale was supported by the sample data,and the fit indexes,uch as GFI,AGFI,NFI and CFI of total scale,were all over 0.9,and RMSEA was lower than 0.08.In addition,the standardized factor loadings of all competence components were 0.393-0.791(P

Objective To develop a mental resilience scale for military personnel and examine the reliability and validity of this scale.MethodsA total of 2611 male officers and soldiers chosen by random cluster sampling to outline the mental resilience scale for military personnel,with the subjects divided into group A and group B.In group A (n=1112) exploratory factor analysis and correlation analysis were used,and in group B (n=1499) confirmatory factor analysis was used.ResultsThe results of exploratory factor analysis and correlation analysis indicated that the Cronbach'? coefficient of total scale was 0.833,and that of subscales was 0.535-0.880;split-half reliability coefficient of total scale was 0.787,and that of subscales 0.339-0.611;retest-reliability coefficient of total scale was 0.401,and that of subscales 0.302-0.668.The correlation coefficients of total scale scores and each factor were 0.445-0.786 (P

Objective To observe the relationship between thyroid hormone levels and reduced pulmonary function in elderly male patients with chronic obstructive pulmonary disease(COPD).Methods One hundred and ninety-five cases of elderly male patients with COPD hospitalized from Jan 2006 to Feb 2010 were enrolled.Thyroid function and lung function(FEV1(forced expiratory volume in 1 second),FEV1/FVC(forced vital capacity))were examined routinely.Pulmonary function was compared between normal group(with normal thyroid function)and lower group(with thyroid hypofunction),thyroid function was also compared in patients with different grade levels(mild,moderate,severe,very severe)of pulmonary function.Results FEV1 and FEV1/FVC in thyroid hypofunction group were significantly decreased compared to the normal group(t =3.582,2.981,respectively,P ＜ 0.01).There was significant difference on T3,FT3 in patients with different grade levels of pulmonary function(F =1.959,1.873,respectively,P ＜ 0.05),among them,T3,FT3 were significantly different between mild group and severe group(P ＜ 0.05),but there was no significant difference in other groups(P ＞0.05).T4、FT4 、TSH displayed no significant difference in all groups(P ＞ 0.05).Conclusion Pulmonary function decreased obviously in elderly old male patients with COPD combined with thyroid hypofunction,and the lower level of thyroid hormone,the worse of pulmonary function.

Objective To formulate the Psychological Core Diathesis Scale for Military Personnel(Part B),and examine the reliability and validity of the scale.Methods Following the psychometric principles,a five factors model of general cognitive ability was firstly constructed by theoretic analysis.The items of initial scale were then developed,followed by repetitive revision and screening for the final establishment of the Psychological Core Diathesis Scale for Military Personnel(Part B),which was composed of 5subtests and 25 items.One thousand and two hundred healthy soldiers were chosen by randomized cluster sampling to participate in the measurement,and 1143valid questionnaires were analyzed for item analysis,Cronbach'?coefficients,split-half reliability and construct validity.Four weeks later,50out of the 1143soldiers were retested for evaluation of the test-retest reliability.Another 200soldiers were randomly collected for the measurement of Intelligence Test for Military Personnel(Part B)as well as the Psychological Core Diathesis Scale for Military Personnel(Part B).The correlation between the results obtained from the 2scales was then analyzed.Soldiers were comprehensively evaluated by their squad leader according to uniform standard.Finally,the top soldiers and ordinary soldiers(50each)were selected by 20 squad leaders from the 1143valid subjects,the scores of the 2groups of soldiers on Psychological Core Diathesis Scale for Military Personnel(Part B)were then compared.Results Item analysis indicated that the average difficulty index of subtests ranged from 0.44to 0.80,the discriminatory power from 0.31to 0.50,and the test-retest correlation coefficient between total scale and subtests from 0.6253 to 0.9558(P

The data of personality investigation of 506 normal adults in Changzhou by using revised EPQ were presented.The results reveal : (1) Little differences of some ubscales from Chinese National Norm were encountered, but overall, there was a high concordance in most part of them. (2) There was a definite relationship between most part of the subscales and age, as well as the sex,(3) There were some correlations between the introvert or extrovert of personality, as well as emotional stability, and the sex. The authors suggest that these results can be used as reference criterion for adult personality norm of Changzhou.

Mental disorders are caused by the synergy of genetic and environmental factors,and epigenetics provides a bridge for mental disorders between environmental exposure and genetic background.This review discussed the role of epigenetics on the development of mental disorders,especially in schizophrenia and depression.DNA methylation,histone acetylation,histone methylation,ncRNA,depressive disorder and schizophrenia were used as searching terms.('Schizophrenia OR depressive disorder') and all field of DNA methylation/histone acetylation/histone methylation/ncRNA were taken as index strategy.67 related articles in database of PubMed,ScienceDirect in March 2017 were acquired.41 articles were enrolled as reviewing materials according to literature screening.Existing researches suggest that epigenetic modifications,including DNA methylation,histone acetylation,histone methylation,and ncRNAs,may be associated with the occurrence of mental illnesses and play key roles in the pathogenesis of mental illnesses,especially in schizophrenia and depression.Further studies on them could provide us novel insights into the pathogenesis of these disorders and effective treatments based upon epigenetic mechanisms.

Objective To develop a new instrument, the resilience scale for military personnel, and examine its reliability and validity. Methods The resilience scale for military personnel was compiled according to open-ended inventory survey . The sample consisted of 860 soldiers, 50 of them were re-tested with the new scale, another 80 tested by Chinese Military Mental Health Scale (CMMHS) at the same time. Factor analysis and Pearson's correlations were used to examine the reliability and validity of the resilience scale for military personnel. Results Based on factor analysis result, 5 factors were extracted, and added 1 lie factor, there were 32 items in theformal scale. The the Cronbach'α of total scale was 0.925, and subscales 0.597～0.810(P<0.01) , split-half reliability was 0.895 of total scale, and 0.384～0.739 of subscales (P < 0.01) ; retest reliability was 0.447 of total scale, and 0.494～0.658 of subscales(P<0.01 or P<0.05). The correlation was significant between the factors of this scale and factors of CMMHS. Conclusion The resilience scale for military personnel has good reliability and validity. The resilience scale has good psychological quality and proves to be applicable to Chinese military personnel in evaluating their resilience.